Motomi Osato

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Yoshiaki ItoProfessor, Cancer Science Institute of Singapore, NUSAdresă de e-mail confirmată pe nus.edu.sg
Katsuya ShigesadaretiredAdresă de e-mail confirmată pe nifty.com
Daniel G TenenCancer Science Institute, National University of SingaporeAdresă de e-mail confirmată pe nus.edu.sg
Wee Joo ChngCancer Science Institute of SingaporeAdresă de e-mail confirmată pe nus.edu.sg
Takuro NakamuraTokyo Medical UniversityAdresă de e-mail confirmată pe umin.net
Minetaro OgawaInstitute of Molecular Embryology and Genetics, Kumamoto UniversityAdresă de e-mail confirmată pe kumamoto-u.ac.jp
Dan LittmanSkirball Institute, NYU School of MedicineAdresă de e-mail confirmată pe med.nyu.edu
Desmond Wai Loon ChinPostdoc, Karolinska InstitutetAdresă de e-mail confirmată pe ki.se
KG YeohNational University of SingaporeAdresă de e-mail confirmată pe nus.edu.sg
Michiaki UnnoTohoku UniveisityAdresă de e-mail confirmată pe surg.med.tohoku.ac.jp
Tuan Zea TanCancer Science Institute of SingaporeAdresă de e-mail confirmată pe nus.edu.sg
Hamish S ScottCenter of Cancer BiologyAdresă de e-mail confirmată pe sa.gov.au
Liqun HuangStony Brook University or National University of SingaporeAdresă de e-mail confirmată pe stonybrookmedicine.edu
Takeshi EgawaWashington University School of MedicineAdresă de e-mail confirmată pe wustl.edu
MJ SunshineUC-San DiegoAdresă de e-mail confirmată pe ucsd.edu
Seiichi MoriGenome Center, Japanese Foundation for Cancer ResearchAdresă de e-mail confirmată pe jfcr.or.jp
Masatsugu EmaShiga University of Medical Science, Research Center for Animal Life Science, Department of Stem Cells and Human Disease ModelsAdresă de e-mail confirmată pe belle.shiga-med.ac.jp
Qi ZengInstitute of Molecular and Cell BiologyAdresă de e-mail confirmată pe imcb.a-star.edu.sg
Stylianos E. AntonarakisProfessor of Genetic Medicine, University of Geneva Medical SchoolAdresă de e-mail confirmată pe unige.ch
Nigel MorrisonGriffith University, Garvan Institute, McGill, ANUAdresă de e-mail confirmată pe griffith.edu.au

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Motomi Osato

Cancer Science Institute, National University of Singapore

Adresă de e-mail confirmată pe nus.edu.sg

Leukemia RUNX Transcription factor cis-regulatory element Mouse model


Titlu Sortați după descrierea bibliografică Sortați după an Sortați după titlu	Citat de Citat de	Anul
Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development I Taniuchi, M Osato, T Egawa, MJ Sunshine, SC Bae, T Komori, Y Ito, ... Cell 111 (5), 621-633, 2002	890	2002
Biallelic and Heterozygous Point Mutations in the Runt Domain of theAML1/PEBP2B Gene Associated With Myeloblastic Leukemias M Osato, N Asou, E Abdalla, K Hoshino, H Yamasaki, T Okubo, ... Blood, The Journal of the American Society of Hematology 93 (6), 1817-1824, 1999	484	1999
In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms … J Michaud, F Wu, M Osato, GM Cottles, M Yanagida, N Asou, ... Blood, The Journal of the American Society of Hematology 99 (4), 1364-1372, 2002	441	2002
MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis CM Koh, M Bezzi, DHP Low, WX Ang, SX Teo, FPH Gay, M Al-Haddawi, ... Nature 523 (7558), 96-100, 2015	420	2015
Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia M Osato Oncogene 23 (24), 4284-4296, 2004	353	2004
Heterozygous PU. 1 mutations are associated with acute myeloid leukemia BU Mueller, T Pabst, M Osato, N Asou, LM Johansen, MD Minden, ... Blood, The Journal of the American Society of Hematology 100 (3), 998-1007, 2002	338	2002
RUNX3 attenuates β-catenin/T cell factors in intestinal tumorigenesis K Ito, ACB Lim, M Salto-Tellez, L Motoda, M Osato, LSH Chuang, ... Cancer cell 14 (3), 226-237, 2008	258	2008
Requirement of Runx1/AML1/PEBP2αB for the generation of haematopoietic cells from endothelial cells T Yokomizo, M Ogawa, M Osato, T Kanno, H Yoshida, T Fujimoto, ... Genes to Cells 6 (1), 13-23, 2001	217	2001
Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia demonstrates novel genotype-phenotype correlations T Yoshida, H Kanegane, M Osato, M Yanagida, T Miyawaki, Y Ito, ... The American Journal of Human Genetics 71 (4), 724-738, 2002	210	2002
Identification of stem cells in the epithelium of the stomach corpus and antrum of mice J Matsuo, S Kimura, A Yamamura, CP Koh, MZ Hossain, DL Heng, ... Gastroenterology 152 (1), 218-231. e14, 2017	156	2017
Integrative analysis of RUNX1 downstream pathways and target genes J Michaud, KM Simpson, R Escher, K Buchet-Poyau, T Beissbarth, ... BMC genomics 9, 1-17, 2008	156	2008
Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis B Jacob, M Osato, N Yamashita, CQ Wang, I Taniuchi, DR Littman, ... Blood, The Journal of the American Society of Hematology 115 (8), 1610-1620, 2010	141	2010
PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo K Guo, J Li, H Wang, M Osato, JP Tang, SY Quah, BQ Gan, Q Zeng Cancer research 66 (19), 9625-9635, 2006	119	2006
A Runx1 Intronic Enhancer Marks Hemogenic Endothelial Cells and Hematopoietic Stem Cells CEL Ng, T Yokomizo, N Yamashita, B Cirovic, H Jin, Z Wen, Y Ito, M Osato Stem cells 28 (10), 1869-1881, 2010	109	2010
Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects CQ Wang, V Krishnan, LS Tay, DWL Chin, CP Koh, JY Chooi, GSS Nah, ... Cell reports 8 (3), 767-782, 2014	108	2014
Requirement for Runx proteins in IgA class switching acting downstream of TGF-β1 and retinoic acid signaling K Watanabe, M Sugai, Y Nambu, M Osato, T Hayashi, M Kawaguchi, ... The Journal of Immunology 184 (6), 2785-2792, 2010	108	2010
Runx1 is involved in primitive erythropoiesis in the mouse T Yokomizo, K Hasegawa, H Ishitobi, M Osato, M Ema, Y Ito, M Yamamoto, ... Blood, The Journal of the American Society of Hematology 111 (8), 4075-4080, 2008	102	2008
Independent origins of fetal liver haematopoietic stem and progenitor cells T Yokomizo, T Ideue, S Morino-Koga, CY Tham, T Sato, N Takeda, ... Nature 609 (7928), 779-784, 2022	100	2022
Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model M Iwasaki, T Kuwata, Y Yamazaki, NA Jenkins, NG Copeland, M Osato, ... Blood 105 (2), 784-793, 2005	99	2005
Runx1 Protects Hematopoietic Stem/Progenitor Cells from Oncogenic Insult L Motoda, M Osato, N Yamashita, B Jacob, LQ Chen, M Yanagida, H Ida, ... Stem cells 25 (12), 2976-2986, 2007	98	2007

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