| Structure-based design of prefusion-stabilized SARS-CoV-2 spikes CL Hsieh, JA Goldsmith, JM Schaub, AM DiVenere, HC Kuo, ... Science 369 (6510), 1501-1505, 2020 | 1225 | 2020 |
| EGFR ligands differentially stabilize receptor dimers to specify signaling kinetics DM Freed, NJ Bessman, A Kiyatkin, E Salazar-Cavazos, PO Byrne, ... Cell 171 (3), 683-695. e18, 2017 | 371 | 2017 |
| How IGF-1 activates its receptor JM Kavran, JM McCabe, PO Byrne, MK Connacher, Z Wang, A Ramek, ... Elife 3, e03772, 2014 | 226 | 2014 |
| Expression of Genes in Cyanobacteria: Adaptation of Endogenous Plasmids as Platforms for High-Level Gene Expression in Synechococcus sp. PCC 7002 Y Xu, RM Alvey, PO Byrne, JE Graham, G Shen, DA Bryant Photosynthesis research protocols, 273-293, 2011 | 168 | 2011 |
| A single ligand is sufficient to activate EGFR dimers P Liu, TE Cleveland IV, S Bouyain, PO Byrne, PA Longo, DJ Leahy Proceedings of the National Academy of Sciences 109 (27), 10861-10866, 2012 | 165 | 2012 |
| The FRET signatures of noninteracting proteins in membranes: simulations and experiments C King, S Sarabipour, P Byrne, DJ Leahy, K Hristova Biophysical journal 106 (6), 1309-1317, 2014 | 106 | 2014 |
| Expression and characterization of SARS-CoV-2 spike proteins JM Schaub, CW Chou, HC Kuo, K Javanmardi, CL Hsieh, J Goldsmith, ... Nature protocols 16 (11), 5339-5356, 2021 | 55 | 2021 |
| Principles and practical applications of structure-based vaccine design PO Byrne, JS McLellan Current Opinion in Immunology 77, 102209, 2022 | 39 | 2022 |
| EGFR forms ligand-independent oligomers that are distinct from the active state PO Byrne, K Hristova, DJ Leahy Journal of Biological Chemistry 295 (38), 13353-13362, 2020 | 35 | 2020 |
| Trimeric SARS-CoV-2 spike proteins produced from CHO cells in bioreactors are high-quality antigens P Pino, J Kint, D Kiseljak, V Agnolon, G Corradin, AV Kajava, P Rovero, ... Processes 8 (12), 1539, 2020 | 26 | 2020 |
| Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein PO Byrne, BE Fisher, DR Ambrozak, EG Blade, Y Tsybovsky, BS Graham, ... Nature communications 14 (1), 1494, 2023 | 19 | 2023 |
| IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern MR Chang, L Tomasovic, NA Kuzmina, AJ Ronk, PO Byrne, R Johnson, ... Nature communications 13 (1), 5814, 2022 | 12 | 2022 |
| Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination WN Voss, ML Mallory, PO Byrne, JM Marchioni, SA Knudson, JM Powers, ... Cell Reports Medicine 5 (8), 2024 | 11 | 2024 |
| Distinctive features of the respiratory syncytial virus priming loop compared to other non-segmented negative strand RNA viruses TN Cressey, AM Shareef, VA Kleiner, SL Noton, PO Byrne, JS McLellan, ... PLoS Pathogens 18 (6), e1010451, 2022 | 11 | 2022 |
| Prefusion stabilization of the Hendra and Langya virus F proteins PO Byrne, EG Blade, BE Fisher, DR Ambrozak, AR Ramamohan, ... Journal of Virology 98 (2), e01372-23, 2024 | 9 | 2024 |
| Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes. bioRxiv. 2020 May 30: 2020.05. 30.125484. doi: 10.1101/2020.05. 30.125484 CL Hsieh, JA Goldsmith, JM Schaub, AM DiVenere, HC Kuo, ... Update: Science, 2020 | 9 | 2020 |
| Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation MR Sponholtz, PO Byrne, AG Lee, AR Ramamohan, JA Goldsmith, ... Proceedings of the National Academy of Sciences 121 (37), e2404250121, 2024 | 7 | 2024 |
| Activity of EGFR transmembrane region variants indicates specific transmembrane dimers are not required for EGFR activity F Bartzoka, M Gonzalez-Magaldi, PO Byrne, NI Callery, K Hristova, ... Biochemical Journal 479 (24), 2465-2475, 2022 | 5 | 2022 |
| Aptasensor-encapsulating semi-permeable proteinosomes for direct target detection in non-treated biofluids J Kim, H Yoo, S Woo, SS Oh Biosensors and Bioelectronics 251, 116062, 2024 | 4 | 2024 |
| Ligand-independent EGFR oligomers do not rely on the active state asymmetric kinase dimer PO Byrne, K Hristova, DJ Leahy bioRxiv, 2020.04. 24.056077, 2020 | 2 | 2020 |
