Dictys: dynamic gene regulatory network dissects developmental continuum with single-cell multiomics L Wang, N Trasanidis, T Wu, G Dong, M Hu, DE Bauer, L Pinello Nature Methods 20 (9), 1368-1378, 2023 | 69 | 2023 |
Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia D Iskander, G Wang, EF Heuston, C Christodoulidou, B Psaila, ... Science translational medicine 13 (610), eabf0113, 2021 | 48 | 2021 |
Systems medicine dissection of chr1q-amp reveals a novel PBX1-FOXM1 axis for targeted therapy in multiple myeloma N Trasanidis, A Katsarou, K Ponnusamy, YA Shen, IV Kostopoulos, ... Blood, The Journal of the American Society of Hematology 139 (13), 1939-1953, 2022 | 30 | 2022 |
Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma J Alvarez-Benayas, N Trasanidis, A Katsarou, K Ponnusamy, A Chaidos, ... Nature communications 12 (1), 5450, 2021 | 29 | 2021 |
The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma K Ponnusamy, MM Tzioni, M Begum, ME Robinson, VS Caputo, ... Haematologica 107 (3), 721, 2021 | 27 | 2021 |
Brd2/4 and Myc regulate alternative cell lineage programmes during early osteoclast differentiation in vitro VS Caputo, N Trasanidis, X Xiao, ME Robinson, A Katsarou, ... IScience 24 (1), 2021 | 17 | 2021 |
Current progress and potential opportunities to infer single-cell developmental trajectory and cell fate L Wang, Q Zhang, Q Qin, N Trasanidis, M Vinyard, H Chen, L Pinello Current opinion in systems biology 26, 1-11, 2021 | 13 | 2021 |
Anopheles coluzzii stearoyl-CoA desaturase is essential for adult female survival and reproduction upon blood feeding Z Ferdous, S Fuchs, V Behrends, N Trasanidis, RM Waterhouse, ... PLoS Pathogens 17 (5), e1009486, 2021 | 10 | 2021 |
MAF functions as a pioneer transcription factor that initiates and sustains myelomagenesis A Katsarou, N Trasanidis, K Ponnusamy, IV Kostopoulos, ... Blood Advances 7 (21), 6395-6410, 2023 | 3 | 2023 |
Over-accessible chromatin links myeloma initiating genetic events to oncogenic transcriptomes and aberrant transcription factor regulatory networks J Alvarez-Benayas, A Katsarou, N Trasanidis, A Chaidos, PC May, ... bioRxiv, 2020.06. 11.140855, 2020 | 2 | 2020 |
Oncogenic MAF in Co-Operation With IRF4 Confers Extensive Chromatin Re-Arrangement in Plasma Cells and Generates ‘Neo-Enhancers’ That Regulate Genes Critical for Myeloma Biology A Katsarou, N Trasanidis, J Alvarez-Benayas, F Papaleonidopoulou, ... Blood 134, 3783, 2019 | 1 | 2019 |
Systems medicine dissection of chromosome 1q amplification reveals oncogenic regulatory circuits and informs targeted therapy in cancer N Trasanidis, A Katsarou, K Ponnusamy, YA Shen, IV Kostopoulos, ... bioRxiv, 2021.11. 17.469031, 2021 | | 2021 |
Single-Cell Transcriptional Landscapes of Human Bone Marrow Reveal Distinct Erythroid Phenotypes Underpinned By Genotype in Diamond-Blackfan Anemia I Deena, W Guanlin, H Elisabeth F, C Chrysi, P Bethan, R Mark E, ... Blood (2020) 136 (Supplement 1): 1–2., 2020 | | 2020 |
The PBX homeobox 1 (PBX1) protein is a novel molecular target for multiple myeloma therapy N Trasanidis Imperial College London, 2020 | | 2020 |
Distinct Chromatin Accessibility Changes, Aberrant Transcription Factor Networks Combined with Novel Oncogenic Enhancers Characterise Myeloma-Initiating Genetic Events N Trasanidis, J Alvarez-Benayas, A Katsarou, A Chaidos, PC May, ... Blood 134, 1769, 2019 | | 2019 |
Myc and Bet Proteins Orchestrate the Early Regulatory Genome Changes Required for Osteoclast Lineage Commitment VS Caputo, N Trasanidis, X Xiao, ME Robinson, A Katsarou, ... Blood 134, 4329, 2019 | | 2019 |
PBX1 Co-Operates with FOXM1 to Regulate Myeloma Cell Proliferation and to Define an Ultra High-Risk chr1q Gain Myeloma Patient Subgroup N Trasanidis, A Katsarou, B Bergonia, K Keren, IV Kostopoulos, ... Blood 134, 3760, 2019 | | 2019 |
Novel ZBP1-IRF3 Dependency in Multiple Myeloma Mediated By IRF3-Driven Regulation of Cell Cycle Genes K Ponnusamy, MM Tzioni, M Begum, ME Robinson, VS Caputo, ... Blood 134, 2521, 2019 | | 2019 |
Myeloma Cell Addiction to the Transcription Factor TCF11 V Caputo, K Goudevenou, N Trasanidis, K Petevi, X Xiao, K Ponnusamy, ... Blood 130, 1194, 2017 | | 2017 |
MOLECULAR CHARACTERIZATION OF THE ANOPHELES PLASMODIUM INTERACTIONS IN THE MOSQUITO MIDGUT VC Ukegbu, E Bushell, N Trasanidis, C Taxiarchi, KA Akinosoglou, J Cho, ... PATHOGENS AND GLOBAL HEALTH 107 (8), 402-402, 2013 | | 2013 |