| The role of mitochondria in insulin resistance and type 2 diabetes mellitus J Szendroedi, E Phielix, M Roden Nature Reviews Endocrinology 8 (2), 92-103, 2012 | 780 | 2012 |
| Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans J Szendroedi, T Yoshimura, E Phielix, C Koliaki, M Marcucci, D Zhang, ... Proceedings of the National Academy of Sciences 111 (26), 9597-9602, 2014 | 461 | 2014 |
| Restoration of muscle mitochondrial function and metabolic flexibility in type 2 diabetes by exercise training is paralleled by increased myocellular fat storage and improved … RCR Meex, VB Schrauwen-Hinderling, E Moonen-Kornips, G Schaart, ... Diabetes 59 (3), 572-579, 2010 | 446 | 2010 |
| Lower intrinsic ADP-stimulated mitochondrial respiration underlies in vivo mitochondrial dysfunction in muscle of male type 2 diabetic patients E Phielix, VB Schrauwen-Hinderling, M Mensink, E Lenaers, R Meex, ... Diabetes 57 (11), 2943-2949, 2008 | 416 | 2008 |
| Type 2 diabetes mellitus and skeletal muscle metabolic function E Phielix, M Mensink Physiology & behavior 94 (2), 252-258, 2008 | 260 | 2008 |
| Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals E Phielix, R Meex, E Moonen-Kornips, MKC Hesselink, P Schrauwen Diabetologia 53, 1714-1721, 2010 | 256 | 2010 |
| Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle J Wefers, D van Moorsel, J Hansen, NJ Connell, B Havekes, J Hoeks, ... Proceedings of the National Academy of Sciences 115 (30), 7789-7794, 2018 | 201 | 2018 |
| Mechanisms of insulin resistance in primary and secondary nonalcoholic fatty liver T Jelenik, K Kaul, G Séquaris, U Flögel, E Phielix, J Kotzka, B Knebel, ... Diabetes 66 (8), 2241-2253, 2017 | 175 | 2017 |
| Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans CME Remie, KHM Roumans, MPB Moonen, NJ Connell, B Havekes, ... The American journal of clinical nutrition 112 (2), 413-426, 2020 | 160 | 2020 |
| Resveratrol as add-on therapy in subjects with well-controlled type 2 diabetes: a randomized controlled trial S Timmers, M De Ligt, E Phielix, T Van De Weijer, J Hansen, ... Diabetes care 39 (12), 2211-2217, 2016 | 140 | 2016 |
| Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 diabetes F Vanweert, P Schrauwen, E Phielix Nutrition & diabetes 12 (1), 35, 2022 | 139 | 2022 |
| Mechanisms underlying the onset of oral lipid–induced skeletal muscle insulin resistance in humans B Nowotny, L Zahiragic, D Krog, PJ Nowotny, C Herder, M Carstensen, ... Diabetes 62 (7), 2240-2248, 2013 | 130 | 2013 |
| Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans T Van De Weijer, E Phielix, L Bilet, EG Williams, ER Ropelle, A Bierwagen, ... Diabetes 64 (4), 1193-1201, 2015 | 125 | 2015 |
| PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans TR Koves, LM Sparks, JP Kovalik, M Mosedale, R Arumugam, KL DeBalsi, ... Journal of lipid research 54 (2), 522-534, 2013 | 120 | 2013 |
| The role of metformin and thiazolidinediones in the regulation of hepatic glucose metabolism and its clinical impact E Phielix, J Szendroedi, M Roden Trends in Pharmacological Sciences 32 (10), 607-616, 2011 | 111 | 2011 |
| High oxidative capacity due to chronic exercise training attenuates lipid-induced insulin resistance E Phielix, R Meex, DM Ouwens, L Sparks, J Hoeks, G Schaart, ... Diabetes 61 (10), 2472-2478, 2012 | 110 | 2012 |
| Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance KHM Roumans, L Lindeboom, P Veeraiah, CME Remie, E Phielix, ... Nature communications 11 (1), 1891, 2020 | 109 | 2020 |
| Relationships between mitochondrial function and metabolic flexibility in type 2 diabetes mellitus T van de Weijer, LM Sparks, E Phielix, RC Meex, NA van Herpen, ... PloS one 8 (2), e51648, 2013 | 97 | 2013 |
| Long–echo time MR spectroscopy for skeletal muscle acetylcarnitine detection L Lindeboom, CI Nabuurs, J Hoeks, B Brouwers, E Phielix, ME Kooi, ... The Journal of clinical investigation 124 (11), 4915-4925, 2014 | 80 | 2014 |
| Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: a randomised controlled trial YMH Bruls, M de Ligt, L Lindeboom, E Phielix, B Havekes, G Schaart, ... EBioMedicine 49, 318-330, 2019 | 71 | 2019 |