Evolution of multifunctionality through a pleiotropic substitution in the innate immune protein S100A9 JL Harman, AN Loes, GD Warren, MC Heaphy, KJ Lampi, MJ Harms Elife 9, e54100, 2020 | 28 | 2020 |
Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA GD Warren, T Kitao, TG Franklin, JV Nguyen, PP Geurink, T Kubori, ... Molecular cell 83 (1), 105-120. e5, 2023 | 20 | 2023 |
Evolution avoids a pathological stabilizing interaction in the immune protein S100A9 JL Harman, PN Reardon, SM Costello, GD Warren, SR Phillips, ... Proceedings of the National Academy of Sciences 119 (41), e2208029119, 2022 | 12 | 2022 |
A functional screen for ubiquitin regulation identifies an E3 ligase secreted by Pseudomonas aeruginosa CG Roberts, S Kaur, AJ Ogden, ME Divine, GD Warren, D Kang, ... bioRxiv, 2024 | | 2024 |
Discovery and characterization of novel ubiquitin-targeted effector proteins in pathogenic bacteria J Pruneda, G Warren, T Franklin, J Nguyen Acta Cryst 78, a193, 2022 | | 2022 |
S100A9S Evolved Potent Proinflammatory Activity and Lost Proteolytic Resistance from a Proteolytically Resistant, Weakly Proinflammatory Ancestor J Harman, A Loes, JA Anderson, G Warren, M Heaphy, K Lampi, ... Biophysical Journal 118 (3), 338a, 2020 | | 2020 |
Ngu en GD Warren, T Kitao, TG Franklin V., Geurink, PP, Kubori, T.,… Pruneda, 105-120, 0 | | |