| Cellular adaptation to hypoxia through hypoxia inducible factors and beyond P Lee, NS Chandel, MC Simon Nature reviews Molecular cell biology 21 (5), 268-283, 2020 | 977 | 2020 |
| Modulating the therapeutic response of tumours to dietary serine and glycine starvation ODK Maddocks, D Athineos, EC Cheung, P Lee, T Zhang, ... Nature 544 (7650), 372-376, 2017 | 581 | 2017 |
| TIGAR is required for efficient intestinal regeneration and tumorigenesis EC Cheung, D Athineos, P Lee, RA Ridgway, W Lambie, C Nixon, ... Developmental cell 25 (5), 463-477, 2013 | 206 | 2013 |
| FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome F Li, P Huangyang, M Burrows, K Guo, R Riscal, J Godfrey, KE Lee, N Lin, ... Nature cell biology 22 (6), 728-739, 2020 | 154 | 2020 |
| Opposing effects of TIGAR-and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine EC Cheung, P Lee, F Ceteci, C Nixon, K Blyth, OJ Sansom, KH Vousden Genes & development 30 (1), 52-63, 2016 | 114 | 2016 |
| Arginase 2 suppresses renal carcinoma progression via biosynthetic cofactor pyridoxal phosphate depletion and increased polyamine toxicity JD Ochocki, S Khare, M Hess, D Ackerman, B Qiu, JI Daisak, AJ Worth, ... Cell metabolism 27 (6), 1263-1280. e6, 2018 | 112 | 2018 |
| Targeting glutamine metabolism slows soft tissue sarcoma growth P Lee, D Malik, N Perkons, P Huangyang, S Khare, S Rhoades, YY Gong, ... Nature communications 11 (1), 498, 2020 | 99 | 2020 |
| TIGAR, TIGAR, burning bright P Lee, KH Vousden, EC Cheung Cancer & metabolism 2, 1-9, 2014 | 95 | 2014 |
| Fructose-1, 6-bisphosphatase 2 inhibits sarcoma progression by restraining mitochondrial biogenesis P Huangyang, F Li, P Lee, I Nissim, AM Weljie, A Mancuso, B Li, B Keith, ... Cell metabolism 31 (1), 174-188. e7, 2020 | 88 | 2020 |
| The intermediate-activity L597VBRAF mutant acts as an epistatic modifier of oncogenic RAS by enhancing signaling through the RAF/MEK/ERK pathway C Andreadi, LK Cheung, S Giblett, B Patel, H Jin, K Mercer, T Kamata, ... Genes & development 26 (17), 1945-1958, 2012 | 77 | 2012 |
| Histone H3.3 beyond cancer: Germline mutations in Histone 3 Family 3A and 3B cause a previously unidentified neurodegenerative disorder in 46 patients L Bryant, D Li, SG Cox, D Marchione, EF Joiner, K Wilson, K Janssen, ... Science advances 6 (49), eabc9207, 2020 | 68 | 2020 |
| iRFP is a sensitive marker for cell number and tumor growth in high-throughput systems AK Hock, P Lee, ODK Maddocks, SM Mason, K Blyth, KH Vousden Cell cycle 13 (2), 220-226, 2014 | 42 | 2014 |
| p53-and p73-independent activation of TIGAR expression in vivo P Lee, AK Hock, KH Vousden, EC Cheung Cell death & disease 6 (8), e1842-e1842, 2015 | 40 | 2015 |
| Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo AK Hock, EC Cheung, TJ Humpton, T Monteverde, V Paulus-Hock, P Lee, ... Scientific Reports 7 (1), 1837, 2017 | 22 | 2017 |
| Abstract A47: The regulation of TIGAR P Lee, EC Cheung, KH Vousden Molecular Cancer Research 14 (1_Supplement), A47-A47, 2016 | | 2016 |
| The regulation of TIGAR P Lee, EC Cheung, KH Vousden Cancer & Metabolism 2, 1-1, 2014 | | 2014 |
| The in vivo function of TIGAR, a p53 target gene that regulates glucose metabolism E Cheung, P Lee, C Berkers, K Blyth, O Sansom, K Vousden Cancer & Metabolism 2, 1-1, 2014 | | 2014 |
| Supplemental Information TIGAR Is Required for Efficient Intestinal Regeneration and Tumorigenesis EC Cheung, D Athineos, P Lee, RA Ridgway, W Lambie, C Nixon, ... | | |
