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Nicolas Delestrée
Nicolas Delestrée
Adresă de e-mail confirmată pe cumc.columbia.edu
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Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit
M Van Alstyne, I Tattoli, N Delestrée, Y Recinos, E Workman, ...
Nature neuroscience 24 (7), 930-940, 2021
1482021
Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis
N Delestrée, M Manuel, C Iglesias, SM Elbasiouny, CJ Heckman, ...
The Journal of physiology 592 (7), 1687-1703, 2014
1442014
The classical complement pathway mediates microglia-dependent remodeling of spinal motor circuits during development and in SMA
A Vukojicic, N Delestrée, EV Fletcher, JG Pagiazitis, S Sankaranarayanan, ...
Cell reports 29 (10), 3087-3100. e7, 2019
1162019
Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA
L Kong, DO Valdivia, CM Simon, CW Hassinan, N Delestrée, DM Ramos, ...
Science translational medicine 13 (578), eabb6871, 2021
902021
Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody
S Cantor, W Zhang, N Delestree, L Remedio, GZ Mentis, SJ Burden
Elife 7, e34375, 2018
792018
Diverging roles for Lrp4 and Wnt signaling in neuromuscular synapse development during evolution
L Remédio, KD Gribble, JK Lee, N Kim, PT Hallock, N Delestrée, ...
Genes & development 30 (9), 1058-1069, 2016
642016
Mixed mode oscillations in mouse spinal motoneurons arise from a low excitability state
C Iglesias, C Meunier, M Manuel, Y Timofeeva, N Delestrée, D Zytnicki
Journal of Neuroscience 31 (15), 5829-5840, 2011
582011
Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS
M Bączyk, NO Alami, N Delestrée, C Martinot, L Tang, B Commisso, ...
Journal of Experimental Medicine 217 (8), 2020
562020
Sumoylation regulates the assembly and activity of the SMN complex
GM Riboldi, I Faravelli, T Kuwajima, N Delestrée, G Dermentzaki, ...
Nature Communications 12 (1), 5040, 2021
142021
Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA. Sci. Transl. Med. 13, eabb6871
L Kong, DO Valdivia, CM Simon, CW Hassinan, N Delestree, DM Ramos, ...
92021
Dysfunction of proprioceptive sensory synapses is a pathogenic event and therapeutic target in mice and humans with spinal muscular atrophy
CM Simon, N Delestree, J Montes, F Gerstner, E Carranza, L Sowoidnich, ...
medRxiv, 2024
72024
Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy
N Delestrée, E Semizoglou, JG Pagiazitis, A Vukojicic, E Drobac, ...
Brain 146 (11), 4574-4593, 2023
42023
Catecholaminergic dysfunction drives postural and locomotor deficits in a mouse model of spinal muscular atrophy
JG Pagiazitis, N Delestrée, L Sowoidnich, N Sivakumar, CM Simon, ...
Cell Reports 44 (1), 2025
12025
Proprioceptive synaptic dysfunction is a key feature in mice and humans with spinal muscular atrophy
CM Simon, N Delestrée, J Montes, L Sowoidnich, F Gerstner, E Carranza, ...
Brain, awaf074, 2025
2025
Excitabilité intrinsèque, couverture synaptique et vacuolisation dendritique des motoneurones spinaux chez la souris SOD1-G93A, modèle de la Sclérose Latérale Amyotrophique
N Delestrée
Université René Descartes-Paris V, 2014
2014
Search Aggiornamenti in Medicina
S Cantor, W Zhang, N Delestrée, L Remédio, GZ Mentis
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Articole 1–16