Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit M Van Alstyne, I Tattoli, N Delestrée, Y Recinos, E Workman, ... Nature neuroscience 24 (7), 930-940, 2021 | 148 | 2021 |
Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis N Delestrée, M Manuel, C Iglesias, SM Elbasiouny, CJ Heckman, ... The Journal of physiology 592 (7), 1687-1703, 2014 | 144 | 2014 |
The classical complement pathway mediates microglia-dependent remodeling of spinal motor circuits during development and in SMA A Vukojicic, N Delestrée, EV Fletcher, JG Pagiazitis, S Sankaranarayanan, ... Cell reports 29 (10), 3087-3100. e7, 2019 | 116 | 2019 |
Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA L Kong, DO Valdivia, CM Simon, CW Hassinan, N Delestrée, DM Ramos, ... Science translational medicine 13 (578), eabb6871, 2021 | 90 | 2021 |
Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody S Cantor, W Zhang, N Delestree, L Remedio, GZ Mentis, SJ Burden Elife 7, e34375, 2018 | 79 | 2018 |
Diverging roles for Lrp4 and Wnt signaling in neuromuscular synapse development during evolution L Remédio, KD Gribble, JK Lee, N Kim, PT Hallock, N Delestrée, ... Genes & development 30 (9), 1058-1069, 2016 | 64 | 2016 |
Mixed mode oscillations in mouse spinal motoneurons arise from a low excitability state C Iglesias, C Meunier, M Manuel, Y Timofeeva, N Delestrée, D Zytnicki Journal of Neuroscience 31 (15), 5829-5840, 2011 | 58 | 2011 |
Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS M Bączyk, NO Alami, N Delestrée, C Martinot, L Tang, B Commisso, ... Journal of Experimental Medicine 217 (8), 2020 | 56 | 2020 |
Sumoylation regulates the assembly and activity of the SMN complex GM Riboldi, I Faravelli, T Kuwajima, N Delestrée, G Dermentzaki, ... Nature Communications 12 (1), 5040, 2021 | 14 | 2021 |
Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA. Sci. Transl. Med. 13, eabb6871 L Kong, DO Valdivia, CM Simon, CW Hassinan, N Delestree, DM Ramos, ... | 9 | 2021 |
Dysfunction of proprioceptive sensory synapses is a pathogenic event and therapeutic target in mice and humans with spinal muscular atrophy CM Simon, N Delestree, J Montes, F Gerstner, E Carranza, L Sowoidnich, ... medRxiv, 2024 | 7 | 2024 |
Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy N Delestrée, E Semizoglou, JG Pagiazitis, A Vukojicic, E Drobac, ... Brain 146 (11), 4574-4593, 2023 | 4 | 2023 |
Catecholaminergic dysfunction drives postural and locomotor deficits in a mouse model of spinal muscular atrophy JG Pagiazitis, N Delestrée, L Sowoidnich, N Sivakumar, CM Simon, ... Cell Reports 44 (1), 2025 | 1 | 2025 |
Proprioceptive synaptic dysfunction is a key feature in mice and humans with spinal muscular atrophy CM Simon, N Delestrée, J Montes, L Sowoidnich, F Gerstner, E Carranza, ... Brain, awaf074, 2025 | | 2025 |
Excitabilité intrinsèque, couverture synaptique et vacuolisation dendritique des motoneurones spinaux chez la souris SOD1-G93A, modèle de la Sclérose Latérale Amyotrophique N Delestrée Université René Descartes-Paris V, 2014 | | 2014 |
Search Aggiornamenti in Medicina S Cantor, W Zhang, N Delestrée, L Remédio, GZ Mentis | | |