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Orna Issler
Orna Issler
NYU Langone, Neuroscience Institute
Adresă de e-mail confirmată pe nyulangone.org - Pagina de pornire
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Sex-specific transcriptional signatures in human depression
B Labonté, O Engmann, I Purushothaman, C Menard, J Wang, C Tan, ...
Nature medicine 23 (9), 1102-1111, 2017
7082017
MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity
O Issler, S Haramati, ED Paul, H Maeno, I Navon, R Zwang, S Gil, ...
Neuron 83 (2), 344-360, 2014
3922014
Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2
CJ Peña, HG Kronman, DM Walker, HM Cates, RC Bagot, ...
Science 356 (6343), 1185-1188, 2017
3892017
Determining the role of microRNAs in psychiatric disorders
O Issler, A Chen
Nature Reviews Neuroscience 16 (4), 201-212, 2015
3552015
Circuit-wide transcriptional profiling reveals brain region-specific gene networks regulating depression susceptibility
RC Bagot, HM Cates, I Purushothaman, ZS Lorsch, DM Walker, J Wang, ...
Neuron 90 (5), 969-983, 2016
3462016
MicroRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34
S Haramati, I Navon, O Issler, G Ezra-Nevo, S Gil, R Zwang, E Hornstein, ...
Journal of Neuroscience 31 (40), 14191-14203, 2011
3032011
Alterations of the host microbiome affect behavioral responses to cocaine
DD Kiraly, DM Walker, ES Calipari, B Labonte, O Issler, CJ Pena, ...
Scientific reports 6 (1), 35455, 2016
2782016
Sex-specific role for the long non-coding RNA LINC00473 in depression
O Issler, YY van der Zee, A Ramakrishnan, J Wang, C Tan, YHE Loh, ...
Neuron 106 (6), 912-926. e5, 2020
1302020
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex
ZS Lorsch, PJ Hamilton, A Ramakrishnan, EM Parise, M Salery, ...
Nature neuroscience 22 (9), 1413-1423, 2019
1142019
Estrogen receptor α drives pro-resilient transcription in mouse models of depression
ZS Lorsch, YHE Loh, I Purushothaman, DM Walker, EM Parise, M Salery, ...
Nature communications 9 (1), 1116, 2018
1082018
Unraveling the epigenetic landscape of depression: focus on early life stress
A Torres-Berrío, O Issler, EM Parise, EJ Nestler
Dialogues in clinical neuroscience 21 (4), 341-357, 2019
1002019
Perifornical Urocortin-3 mediates the link between stress-induced anxiety and energy homeostasis
Y Kuperman, O Issler, L Regev, I Musseri, I Navon, A Neufeld-Cohen, ...
Proceedings of the National Academy of Sciences 107 (18), 8393-8398, 2010
912010
Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons
H Kronman, A Torres-Berrío, S Sidoli, O Issler, A Godino, A Ramakrishnan, ...
Nature neuroscience 24 (5), 667-676, 2021
882021
ACTH-dependent regulation of microRNA as endogenous modulators of glucocorticoid receptor expression in the adrenal gland
A Riester, O Issler, A Spyroglou, SH Rodrig, A Chen, F Beuschlein
Endocrinology 153 (1), 212-222, 2012
792012
Aberrant H3. 3 dynamics in NAc promote vulnerability to depressive-like behavior
AE Lepack, RC Bagot, CJ Peña, YHE Loh, LA Farrelly, Y Lu, SK Powell, ...
Proceedings of the National Academy of Sciences 113 (44), 12562-12567, 2016
652016
Tet1 in nucleus accumbens opposes depression-and anxiety-like behaviors
J Feng, CJ Pena, I Purushothaman, O Engmann, D Walker, AN Brown, ...
Neuropsychopharmacology 42 (8), 1657-1669, 2017
642017
Overexpression of corticotropin-releasing factor receptor type 2 in the bed nucleus of stria terminalis improves posttraumatic stress disorder-like symptoms in a model of …
E Elharrar, G Warhaftig, O Issler, Y Sztainberg, Y Dikshtein, R Zahut, ...
Biological psychiatry 74 (11), 827-836, 2013
582013
Cocaine-induced chromatin modifications associate with increased expression and three-dimensional looping of Auts2
O Engmann, B Labonté, A Mitchell, P Bashtrykov, ES Calipari, ...
Biological psychiatry 82 (11), 794-805, 2017
542017
Gadd45b mediates depressive-like role through DNA demethylation
B Labonté, YH Jeong, E Parise, O Issler, M Fatma, O Engmann, KA Cho, ...
Scientific reports 9 (1), 4615, 2019
512019
Chronic activation of corticotropin-releasing factor type 2 receptors reveals a key role for 5-HT1A receptor responsiveness in mediating behavioral and serotonergic responses …
A Neufeld-Cohen, PAT Kelly, ED Paul, RN Carter, E Skinner, ...
Biological psychiatry 72 (6), 437-447, 2012
512012
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