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muralikrishna akula
muralikrishna akula
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Antioxidants can increase melanoma metastasis in mice
K Le Gal, MX Ibrahim, C Wiel, VI Sayin, MK Akula, C Karlsson, MG Dalin, ...
Science translational medicine 7 (308), 308re8-308re8, 2015
7032015
Control of the innate immune response by the mevalonate pathway
MK Akula, M Shi, Z Jiang, CE Foster, D Miao, AS Li, X Zhang, RM Gavin, ...
Nature immunology 17 (8), 922-929, 2016
1932016
Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria
MX Ibrahim, VI Sayin, MK Akula, M Liu, LG Fong, SG Young, MO Bergo
Science 340 (6138), 1330-1333, 2013
1382013
Inhibition of mevalonate pathway prevents adipocyte browning in mice and men by affecting protein prenylation
M Balaz, AS Becker, L Balazova, L Straub, J Müller, G Gashi, CI Maushart, ...
Cell metabolism 29 (4), 901-916. e8, 2019
832019
Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions
MK Akula, MX Ibrahim, EG Ivarsson, OM Khan, IT Kumar, M Erlandsson, ...
Nature communications 10 (1), 3975, 2019
752019
Targeting filamin A reduces macrophage activity and atherosclerosis
S Bandaru, C Ala, R Salimi, MK Akula, M Ekstrand, S Devarakonda, ...
Circulation 140 (1), 67-79, 2019
532019
Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice
OM Khan, MK Akula, K Skålen, C Karlsson, M Ståhlman, SG Young, ...
Circulation 127 (7), 782-790, 2013
532013
Lack of RAC1 in macrophages protects against atherosclerosis
S Bandaru, C Ala, M Ekstrand, MK Akula, M Pedrelli, X Liu, G Bergström, ...
PLoS One 15 (9), e0239284, 2020
172020
Knockout of the RAS endoprotease RCE1 accelerates myeloid leukemia by downregulating GADD45b
C Karlsson, MK Akula, A Staffas, J Cisowski, VI Sayin, MX Ibrahim, ...
Leukemia 35 (2), 606-609, 2021
72021
Rho-GTPase dependent leukocyte interaction generates pro-inflammatory thymic Tregs and causes arthritis
E Malmhäll-Bah, KME Andersson, MC Erlandsson, MK Akula, M Brisslert, ...
Journal of Autoimmunity 130, 102843, 2022
42022
OP0022 RHO EXPRESSION FACILITATES T CELL MIGRATION TO LYMPH NODES IN RESPONSE INFLAMMATION
E Malmhäll-Bah, KM Andersson, MC Erlandsson, M Brisslert, O Khan, ...
Annals of the Rheumatic Diseases 80, 12-13, 2021
2021
OP0334 GGTASE DEFICIENT MACROPHAGES ALTER INTEGRIN EXPRESSION ON LYMPHOCYTES AND FACILITATE DEVELOPMENT OF ARTHRITIS
KM Andersson, E Malmhäll-Bah, MC Erlandsson, M Brisslert, M Akula, ...
Annals of the Rheumatic Diseases 79, 205-206, 2020
2020
Defining the importance of protein geranylgeranylation in innate immunity
NVM Akula
2018
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