Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER T Van Den Beucken, E Koch, K Chu, R Rupaimoole, P Prickaerts, ... Nature communications 5 (1), 5203, 2014 | 242 | 2014 |
Bilberries reduce low‐grade inflammation in individuals with features of metabolic syndrome M Kolehmainen, O Mykkänen, PV Kirjavainen, T Leppänen, E Moilanen, ... Molecular nutrition & food research 56 (10), 1501-1510, 2012 | 219 | 2012 |
A common genetic variant within SCN10A modulates cardiac SCN5A expression M Van Den Boogaard, S Smemo, O Burnicka-Turek, DE Arnolds, ... The Journal of clinical investigation 124 (4), 1844-1852, 2014 | 213 | 2014 |
Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16 HJ Cordell, J Bentham, A Topf, D Zelenika, S Heath, C Mamasoula, ... Nature genetics 45 (7), 822-824, 2013 | 174 | 2013 |
User-friendly solutions for microarray quality control and pre-processing on ArrayAnalysis. org LMT Eijssen, M Jaillard, ME Adriaens, S Gaj, PJ de Groot, M Müller, ... Nucleic acids research 41 (W1), W71-W76, 2013 | 163 | 2013 |
Mapping of lamin A-and progerin-interacting genome regions N Kubben, M Adriaens, W Meuleman, JW Voncken, B van Steensel, ... Chromosoma 121, 447-464, 2012 | 101 | 2012 |
Phenotypic clustering of dilated cardiomyopathy patients highlights important pathophysiological differences JAJ Verdonschot, M Merlo, F Dominguez, P Wang, MTHM Henkens, ... European heart journal 42 (2), 162-174, 2021 | 95 | 2021 |
Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3 P Prickaerts, ME Adriaens, T Beucken, E Koch, L Dubois, VEH Dahlmans, ... Epigenetics & chromatin 9, 1-19, 2016 | 91 | 2016 |
Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy M Heinig, ME Adriaens, S Schafer, H van Deutekom, EM Lodder, JS Ware, ... Genome biology 18 (1), 170, 2017 | 83 | 2017 |
Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway RJ Orton, ME Adriaens, A Gormand, OE Sturm, W Kolch, DR Gilbert BMC systems biology 3, 1-17, 2009 | 83 | 2009 |
Coxsackie and adenovirus receptor is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemia RFJ Marsman, CR Bezzina, F Freiberg, AO Verkerk, ME Adriaens, ... Journal of the American College of Cardiology 63 (6), 549-559, 2014 | 74 | 2014 |
Genome-wide identification of expression quantitative trait loci (eQTLs) in human heart TT Koopmann, ME Adriaens, PD Moerland, RF Marsman, ML Westerveld, ... PloS one 9 (5), e97380, 2014 | 63 | 2014 |
The public road to high-quality curated biological pathways ME Adriaens, M Jaillard, A Waagmeester, SLM Coort, AR Pico, CTA Evelo Drug discovery today 13 (19-20), 856-862, 2008 | 63 | 2008 |
From SNPs to pathways: Biological interpretation of type 2 diabetes (T2DM) genome wide association study (GWAS) results E Cirillo, M Kutmon, M Gonzalez Hernandez, T Hooimeijer, ME Adriaens, ... PloS one 13 (4), e0193515, 2018 | 62 | 2018 |
Subcutaneous adipose tissue and systemic inflammation are associated with peripheral but not hepatic insulin resistance in humans BW Van der Kolk, M Kalafati, M Adriaens, MMJ Van Greevenbroek, ... Diabetes 68 (12), 2247-2258, 2019 | 59 | 2019 |
Identification of novel ER-α target genes in breast cancer cells: Gene-and cell-selective co-regulator recruitment at target promoters determines the response to 17β-estradiol … A Romano, M Adriaens, S Kuenen, B Delvoux, G Dunselman, C Evelo, ... Molecular and cellular endocrinology 314 (1), 90-100, 2010 | 49 | 2010 |
Genome-wide polyadenylation maps reveal dynamic mRNA 3′-end formation in the failing human heart EE Creemers, A Bawazeer, AP Ugalde, HWM van Deutekom, ... Circulation research 118 (3), 433-438, 2016 | 48 | 2016 |
Bilberries potentially alleviate stress-related retinal gene expression induced by a high-fat diet in mice OT Mykkänen, G Kalesnykas, M Adriaens, CT Evelo, R Törrönen, ... Molecular Vision 18, 2338, 2012 | 39 | 2012 |
Cardiometabolic health improvements upon dietary intervention are driven by tissue-specific insulin resistance phenotype: a precision nutrition trial I Trouwborst, A Gijbels, KM Jardon, E Siebelink, GB Hul, L Wanders, ... Cell Metabolism 35 (1), 71-83. e5, 2023 | 37 | 2023 |
Exploring the cellular network of metabolic flexibility in the adipose tissue SHK Tareen, M Kutmon, ME Adriaens, ECM Mariman, TM de Kok, ... Genes & nutrition 13, 1-8, 2018 | 26 | 2018 |