Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome X Carvajal-Vergara, A Sevilla, SL D’Souza, YS Ang, C Schaniel, DF Lee, ... Nature 465 (7299), 808-812, 2010 | 830 | 2010 |
Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network YS Ang, SY Tsai, DF Lee, J Monk, J Su, K Ratnakumar, J Ding, Y Ge, ... Cell 145 (2), 183-197, 2011 | 669 | 2011 |
TGF-β tumor suppression through a lethal EMT CJ David, YH Huang, M Chen, J Su, Y Zou, N Bardeesy, ... Cell 164 (5), 1015-1030, 2016 | 632 | 2016 |
TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1 J Su, SM Morgani, CJ David, Q Wang, EE Er, YH Huang, H Basnet, Y Zou, ... Nature 577 (7791), 566-571, 2020 | 405 | 2020 |
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells X Zhang, S Yalcin, DF Lee, TYJ Yeh, SM Lee, J Su, SK Mungamuri, ... Nature cell biology 13 (9), 1092-1099, 2011 | 312 | 2011 |
Modeling familial cancer with induced pluripotent stem cells DF Lee, J Su, HS Kim, B Chang, D Papatsenko, R Zhao, Y Yuan, ... Cell 161 (2), 240-254, 2015 | 232 | 2015 |
The p53 family coordinates Wnt and nodal inputs in mesendodermal differentiation of embryonic stem cells Q Wang, Y Zou, S Nowotschin, SY Kim, QV Li, CL Soh, J Su, C Zhang, ... Cell stem cell 20 (1), 70-86, 2017 | 176 | 2017 |
Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling DF Lee, J Su, YS Ang, X Carvajal-Vergara, S Mulero-Navarro, CF Pereira, ... Cell stem cell 11 (2), 179-194, 2012 | 161 | 2012 |
Epigenetic roles of MLL oncoproteins are dependent on NF-κB HP Kuo, Z Wang, DF Lee, M Iwasaki, J Duque-Afonso, SHK Wong, CH Lin, ... Cancer cell 24 (4), 423-437, 2013 | 94 | 2013 |
Myeloid dysregulation in a human induced pluripotent stem cell model of PTPN11-associated juvenile myelomonocytic leukemia S Mulero-Navarro, A Sevilla, AC Roman, DF Lee, SL D’Souza, S Pardo, ... Cell reports 13 (3), 504-515, 2015 | 93 | 2015 |
Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling E Aragón, Q Wang, Y Zou, SM Morgani, L Ruiz, Z Kaczmarska, J Su, ... Genes & development 33 (21-22), 1506-1524, 2019 | 87 | 2019 |
Oncogenic role of SFRP2 in p53-mutant osteosarcoma development via autocrine and paracrine mechanism H Kim, S Yoo, R Zhou, A Xu, JM Bernitz, Y Yuan, AM Gomes, MG Daniel, ... Proceedings of the National Academy of Sciences 115 (47), E11128-E11137, 2018 | 60 | 2018 |
Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency DF Lee, J Su, A Sevilla, J Gingold, C Schaniel, IR Lemischka Nature protocols 7 (4), 729-748, 2012 | 45 | 2012 |
Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies J Tu, Z Huo, Y Yu, D Zhu, A Xu, MF Huang, R Hu, R Wang, JA Gingold, ... Proceedings of the National Academy of Sciences 119 (16), e2117857119, 2022 | 24 | 2022 |
Genomic integrity safeguards self-renewal in embryonic stem cells J Su, D Zhu, Z Huo, JA Gingold, YS Ang, J Tu, R Zhou, Y Lin, H Luo, ... Cell reports 28 (6), 1400-1409. e4, 2019 | 18 | 2019 |
The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos SM Morgani, J Su, J Nichols, J Massagué, AK Hadjantonakis Elife 10, e64811, 2021 | 12 | 2021 |
Distribution Analyzer, a methodology for identifying and clustering outlier conditions from single-cell distributions, and its application to a Nanog reporter RNAi screen JA Gingold, ES Coakley, J Su, DF Lee, Z Lau, H Zhou, DP Felsenfeld, ... BMC bioinformatics 16, 1-20, 2015 | 11 | 2015 |
An esrrb and nanog cell fate regulatory module controlled by feed forward loop interactions A Sevilla, D Papatsenko, AR Mazloom, H Xu, A Vasileva, RD Unwin, ... Frontiers in cell and developmental biology 9, 630067, 2021 | 8 | 2021 |
Rimmele ́ X Zhang, S Yalcin, DF Lee, TYJ Yeh, SM Lee, J Su, SK Mungamuri P., Kennedy, M., Sellers, R. et al, 1092-1099, 2011 | 6 | 2011 |
Model osteosarcoma by Li-Fraumeni syndrome patient-specific induced pluripotent stem cells DF Lee, J Su, HS Kim, B Chang, R Zhao, D Papatsenko, Y Yuan, ... Cancer Research 75 (15_Supplement), 5129-5129, 2015 | 1 | 2015 |