| Metabolic support of tumour-infiltrating regulatory T cells by lactic acid MLJ Watson, PDA Vignali, SJ Mullett, AE Overacre-Delgoffe, RM Peralta, ... Nature 591 (7851), 645-651, 2021 | 812 | 2021 |
| Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion NE Scharping, DB Rivadeneira, AV Menk, PDA Vignali, BR Ford, ... Nature immunology 22 (2), 205-215, 2021 | 580 | 2021 |
| YAP is essential for treg-mediated suppression of antitumor immunity X Ni, J Tao, J Barbi, Q Chen, BV Park, Z Li, N Zhang, A Lebid, ... Cancer discovery 8 (8), 1026-1043, 2018 | 195 | 2018 |
| Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity PDA Vignali, K DePeaux, MLJ Watson, C Ye, BR Ford, K Lontos, ... Nature immunology 24 (2), 267-279, 2023 | 156 | 2023 |
| MicroRNA-17 modulates regulatory T cell function by targeting co-regulators of the Foxp3 transcription factor HY Yang, J Barbi, CY Wu, Y Zheng, PDA Vignali, X Wu, JH Tao, BV Park, ... Immunity 45 (1), 83-93, 2016 | 96 | 2016 |
| Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells BR Ford, PDA Vignali, NL Rittenhouse, NE Scharping, R Peralta, ... Science immunology 7 (74), eabj9123, 2022 | 67 | 2022 |
| Hypoxia reduction sensitizes refractory cancers to immunotherapy P Jayaprakash, PDA Vignali, GM Delgoffe, MA Curran Annual Review of Medicine 73 (1), 251-265, 2022 | 53 | 2022 |
| Rapid profiling cell cycle by flow cytometry using concurrent staining of DNA and mitotic markers Y Shen, P Vignali, R Wang Bio-protocol 7 (16), e2517-e2517, 2017 | 52 | 2017 |
| Metabolic regulation of T cell immunity PDA Vignali, J Barbi, F Pan Immune Metabolism in Health and Tumor, 87-130, 2017 | 11 | 2017 |
| The neurotrophic factor neuritin maintains and promotes the function of regulatory T cells in autoimmunity and cancer JJ Barbi, PDA Vignali, H Yu, F Pan, D Pardoll The Journal of Immunology 196 (1_Supplement), 58.12-58.12, 2016 | 8 | 2016 |
| Altered costimulatory signals and hypoxia support chromatin landscapes limiting the functional potential of exhausted T cells in cancer BR Ford, NL Rittenhouse, NE Scharping, PDA Vignali, AT Frisch, ... BioRxiv, 2021.07. 11.451947, 2021 | 4 | 2021 |
| 589 Efficacy of oncolytic vaccinia virus requires infection of suppressive immune cells in the tumor microenvironment leading to their reprogramming and deletion K DePeaux, P Vignali, S Sarkar, G Delgoffe Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | 3 | 2020 |
| Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity H Yu, H Nishio, J Barbi, M Mitchell-Flack, PDA Vignali, Y Zheng, A Lebid, ... eLife 13, RP96812, 2024 | 2 | 2024 |
| 512 Terminally exhausted CD8+ T cells potentiate the tolerogenic tumor microenvironment as functional suppressors P Vignali, K DePeaux, ML Watson, A Menk, N Scharping, G Delgoffe Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | 2 | 2020 |
| 679 tumor hypoxia drives suppressor function in exhausted T cells limiting antitumor immunity P Vignali, K DePeaux, ML Watson, N Scharping, A Menk, G Delgoffe Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | 1 | 2021 |
| Unraveling the therapeutic benefit of sequenced chemo-immunotherapy PDA Vignali, JJ Luke Clinical Cancer Research 30 (9), 1705-1707, 2024 | | 2024 |
| Research briefing GM Delgoffe, PDA Vignali Nature Immunology 24, 218-219, 2023 | | 2023 |
| The neurotrophic factor Neuritin regulates T cell anergy and T regulatory cell function H Yu, H Nishio, J Barbi, M Mitchell-Flack, P Vignali, Y Zheng, A Lebid, ... The Journal of Immunology 208 (Supplement_1), 56.03-56.03, 2022 | | 2022 |
| Metabolic support of regulatory T cells by lactic acid MLJ Watson, PDA Vignali, SJ Mullett, AE Overacre, RM Peralta, ... University of Pittsburgh, 2022 | | 2022 |
| 644 Tumor-mediated suppressive signaling and hypoxia supports altered chromatin landscapes that limit the transcriptional and functional potential of terminal T cell exhaustion F Rhodes, N Rittenhouse, N Scharping, P Vignali, G Delgoffe, A Poholek Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A673-A673, 2021 | | 2021 |
