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Kathryn Beabout
Kathryn Beabout
Research Scientist, Air Force Research Laboratory
Adresă de e-mail confirmată pe us.af.mil - Pagina de pornire
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The ribosomal S10 protein is a general target for decreased tigecycline susceptibility
K Beabout, TG Hammerstrom, AM Perez, BF Magalhães, AG Prater, ...
Antimicrobial agents and chemotherapy 59 (9), 5561-5566, 2015
1362015
Quantification of interlaboratory cell-free protein synthesis variability
SD Cole, K Beabout, KB Turner, ZK Smith, VL Funk, SV Harbaugh, ...
ACS Synthetic Biology 8 (9), 2080-2091, 2019
842019
Acinetobacter baumannii repeatedly evolves a hypermutator phenotype in response to tigecycline that effectively surveys evolutionary trajectories to resistance
TG Hammerstrom, K Beabout, TP Clements, G Saxer, Y Shamoo
PloS one 10 (10), e0140489, 2015
662015
Total synthesis of viridicatumtoxin B and analogues thereof: strategy evolution, structural revision, and biological evaluation
KC Nicolaou, CRH Hale, C Nilewski, HA Ioannidou, A ElMarrouni, ...
Journal of the American Chemical Society 136 (34), 12137-12160, 2014
612014
The essential role of hypermutation in rapid adaptation to antibiotic stress
HH Mehta, AG Prater, K Beabout, RAL Elworth, M Karavis, HS Gibbons, ...
Antimicrobial agents and chemotherapy 63 (7), 10.1128/aac. 00744-19, 2019
552019
Rampant parasexuality evolves in a hospital pathogen during antibiotic selection
K Beabout, TG Hammerstrom, TT Wang, M Bhatty, PJ Christie, G Saxer, ...
Molecular biology and evolution 32 (10), 2585-2597, 2015
362015
Asymmetric alkylation of anthrones, enantioselective total synthesis of (−)-and (+)-viridicatumtoxins B and analogues thereof: absolute configuration and potent antibacterial …
KC Nicolaou, G Liu, K Beabout, MD McCurry, Y Shamoo
Journal of the American Chemical Society 139 (10), 3736-3746, 2017
352017
Daptomycin resistance in Enterococcus faecium can be delayed by disruption of the LiaFSR stress response pathway
AG Prater, HH Mehta, K Beabout, A Supandy, WR Miller, TT Tran, ...
Antimicrobial Agents and Chemotherapy 65 (4), 10.1128/aac. 01317-20, 2021
272021
Optimization of heavy metal sensors based on transcription factors and cell-free expression systems
K Beabout, CB Bernhards, M Thakur, KB Turner, SD Cole, SA Walper, ...
ACS Synthetic Biology 10 (11), 3040-3054, 2021
252021
Enantioselective total synthesis of antibiotic CJ-16,264, synthesis and biological evaluation of designed analogues, and discovery of highly potent and simpler antibacterial agents
KC Nicolaou, KK Pulukuri, S Rigol, M Buchman, AA Shah, N Cen, ...
Journal of the American Chemical Society 139 (44), 15868-15877, 2017
242017
Impact of Porous Matrices and Concentration by Lyophilization on Cell-Free Expression
SM Blum, MS Lee, GE Mgboji, VL Funk, K Beabout, SV Harbaugh, ...
ACS Synthetic Biology 10 (5), 1116-1131, 2021
152021
Enantioselective N-alkylation of nitroindoles under Phase-Transfer catalysis
D Trubitsõn, J Martõnova, K Erkman, A Metsala, J Saame, K Kõster, ...
Synthesis 52 (07), 1047-1059, 2020
122020
Detection of bile acids in complex matrices using a transcription factor-based biosensor
K Beabout, AM Ehrenworth Breedon, SM Blum, AE Miklos, MW Lux, ...
ACS Biomaterials Science & Engineering 9 (9), 5151-5162, 2022
82022
Experimental evolution of diverse strains as a method for the determination of biochemical mechanisms of action for novel pyrrolizidinone antibiotics
K Beabout, MD McCurry, H Mehta, AA Shah, KK Pulukuri, S Rigol, ...
ACS infectious diseases 3 (11), 854-865, 2017
52017
Incoherent merger network for robust ratiometric gene expression response
U Kwon, HH Huang, JL Chávez, K Beabout, S Harbaugh, D Del Vecchio
Nucleic Acids Research 51 (6), 2963-2973, 2023
22023
Microbial Bioheater Driven by the Alternative Oxidase Metabolic Pathway
J Chávez, V Williams, K Beabout, S Harbaugh
2025
Engineered Incoherent Feedforward Loops for Robust Ratiometric Sensing in Bacteria
U Kwon, HH Huang, J Chávez, K Beabout, S Harbaugh, D Del Vecchio
2024 Synthetic Biology: Engineering, Evolution & Design (SEED), 2024
2024
Microneedle Bio-Patch for Monitoring and Augmentation of Human Health and Performance
I Drachuk, K Beabout, C McPherson, J Chávez, S Harbaugh
2024 Synthetic Biology: Engineering, Evolution & Design (SEED), 2024
2024
Development of Semi-Specific Transcription Factor Arrays for Biosignature Sensing
K Beabout, S Harbaugh, S d'Oelsnitz, A Ellington, J Chávez
2024 Synthetic Biology: Engineering, Evolution & Design (SEED), 2024
2024
Biological Sensors for Microbiome Diagnostics
AM Ehrenworth Breedon, KR Beabout, HG Coia, CM Davis, SV Harbaugh, ...
Principles in Microbiome Engineering, 155-194, 2022
2022
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