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Kathrin Leppek
Kathrin Leppek
TT W1/2 Prof at Uni Clinic Bonn / Uni Bonn; Postdoc: Stanford, PhD: DKFZ/Uni Heidelberg
Adresă de e-mail confirmată pe uni-bonn.de - Pagina de pornire
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Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them
K Leppek, R Das, M Barna
Nature Reviews Molecular Cell Biology 19 (3), 158-174, 2018
9112018
The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity
D Simsek, GC Tiu, RA Flynn, GW Byeon, K Leppek, AF Xu, HY Chang, ...
Cell 169 (6), 1051-1065. e18, 2017
4392017
Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs
K Leppek, J Schott, S Reitter, F Poetz, MC Hammond, G Stoecklin
Cell 153 (4), 869-881, 2013
3572013
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
K Leppek, GW Byeon, W Kladwang, HK Wayment-Steele, CH Kerr, AF Xu, ...
Nature communications 13 (1), 1536, 2022
2382022
An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins
K Leppek, G Stoecklin
Nucleic Acids Research 42 (2), e13-e13, 2014
1682014
Genome-wide assessment of AU-rich elements by the ARE score algorithm
M Spasic, CC Friedel, J Schott, J Kreth, K Leppek, S Hofmann, S Ozgur, ...
PLoS Genetics 8 (1), e1002433, 2012
912012
Gene-and Species-Specific Hox mRNA Translation by Ribosome Expansion Segments
K Leppek, K Fujii, N Quade, TT Susanto, D Boehringer, T Lenarčič, S Xue, ...
Molecular Cell 80 (6), 980-995. e13, 2020
572020
VELCRO-IP RNA-seq reveals ribosome expansion segment function in translation genome-wide
K Leppek, GW Byeon, K Fujii, M Barna
Cell Reports 34 (3), 108629, 2021
162021
A distinct, sequence-induced conformation is required for recognition of the constitutive decay element RNA by roquin
L Codutti, K Leppek, J Zálešák, V Windeisen, P Masiewicz, G Stoecklin, ...
Structure 23 (8), 1437-1447, 2015
142015
An rRNA variant to deal with stress
K Leppek, M Barna
Nature Microbiology 4 (3), 382-383, 2019
72019
Protein synthesis and translational control: at eye level with the ribosome
K Leppek, J Schott, G Stoecklin
EMBO Reports 12 (12), 1214-1216, 2011
32011
Systems and Methods to Assess RNA Stability
M Barna, R Das, K Leppek, GW Byeon, E Sharma
US Patent App. 17/456,353, 2022
22022
Systems and methods to assess RNA stability
M Barna, K Leppek, GW Byeon
US Patent 11,739,317, 2023
12023
VELCRO-IP RNA-seq explores ribosome expansion segment function in translation genome-wide
K Leppek, GW Byeon, K Fujii, M Barna
bioRxiv, 2020.07. 01.179515, 2020
12020
Gene-and Species-Specific Translation by Ribosome Expansion Segments
K Leppek, K Fujii, N Quade, TT Susanto, D Boehringer, T Lenarčič, S Xue, ...
Available at SSRN 3634264, 2020
12020
RNA Affinity Purification and Characterization of Roquin Proteins in CDE-mediated mRNA Decay
K Leppek
Universität Heidelberg, 2014
12014
Systems and Methods for Enhancing Gene Expression
M Barna, K Leppek
US Patent App. 17/998,788, 2024
2024
Systems and Methods for Enhancing Gene Expression
M Barna, K Leppek
US Patent App. 17/998,789, 2024
2024
Systems and Methods for Producing RNA Constructs with Increased Translation and Stability
M Barna, K Leppek, GW Byeon
US Patent App. 18/053,324, 2023
2023
Systems and methods for producing RNA constructs with increased translation and stability
M Barna, K Leppek, GW Byeon
US Patent 11,492,611, 2022
2022
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