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Phillip J. White
Phillip J. White
Associate Professor @ Duke Molecular Physiology Institute
Adresă de e-mail confirmată pe duke.edu - Pagina de pornire
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Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding
N Turner, GM Kowalski, SJ Leslie, S Risis, C Yang, RS Lee-Young, ...
Diabetologia 56 (7), 1638-1648, 2013
4872013
BCAA catabolism in brown fat controls energy homeostasis through SLC25A44
T Yoneshiro, Q Wang, K Tajima, M Matsushita, H Maki, K Igarashi, Z Dai, ...
Nature, 1-6, 2019
4542019
The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase
PJ White, RW McGarrah, PA Grimsrud, SC Tso, WH Yang, JM Haldeman, ...
Cell Metabolism, 2018
3022018
Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export
Phillip J. White, Amanda L. Lapworth, Jie An, Liping Wang, Robert W ...
Molecular Metabolism, 2016
2832016
Branched-chain amino acids in disease Are BCAAs a biomarker, causal agent, or both in cardiometabolic disease?
PJ White, CB Newgard
Science 363 (6427), 582-583, 2019
2682019
Insulin Reverses the High-Fat Diet–Induced Increase in Brain Aβ and Improves Memory in an Animal Model of Alzheimer Disease
M Vandal, PJ White, C Tremblay, I St-Amour, G Chevrier, V Emond, ...
Diabetes 63 (12), 4291-4301, 2014
2582014
Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in …
PJ White, M Arita, R Taguchi, JX Kang, A Marette
Diabetes 59 (12), 3066-3073, 2010
2342010
Long-chain omega-3 fatty acids regulate bovine whole-body protein metabolism by promoting muscle insulin signalling to the Akt–mTOR–S6K1 pathway and insulin sensitivity
AA Gingras, PJ White, PY Chouinard, P Julien, TA Davis, L Dombrowski, ...
The Journal of physiology 579 (1), 269-284, 2007
2332007
Insulin action, type 2 diabetes, and branched-chain amino acids: a two-way street
PJ White, RW McGarrah, MA Herman, JR Bain, SH Shah, CB Newgard
Molecular Metabolism, 101261, 2021
2232021
Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression
RE Ericksen, SL Lim, E McDonnell, WH Shuen, M Vadiveloo, PJ White, ...
Cell Metabolism, 2019
2232019
Brain Insulin Lowers Circulating BCAA Levels by Inducing Hepatic BCAA Catabolism
AC Shin, M Fasshauer, N Filatova, LA Grundell, E Zielinski, JY Zhou, ...
Cell metabolism 20 (5), 898-909, 2014
1662014
Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans.
KWE Glynn EL, Piner LW, Huffman KM, Slentz CA, Elliot-Penry L, AbouAssi H ...
Diabetologia, 2015
1572015
Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis
PJ White, P St-Pierre, A Charbonneau, PL Mitchell, E St-Amand, ...
Nature medicine 20 (6), 664-669, 2014
1412014
Branched-chain amino acids in cardiovascular disease
RW McGarrah, PJ White
Nature Reviews Cardiology 20 (2), 77-89, 2023
1402023
Differential effects of various fish proteins in altering body weight, adiposity, inflammatory status, and insulin sensitivity in high-fat–fed rats
G Pilon, J Ruzzin, LE Rioux, C Lavigne, PJ White, L Frøyland, H Jacques, ...
Metabolism 60 (8), 1122-1130, 2011
1362011
Age-dependent impairment of glucose tolerance in the 3xTg-AD mouse model of Alzheimer’s disease
M Vandal, PJ White, G Chevrier, C Tremblay, IS Amour, E Planel, ...
The FASEB Journal 29 (10), 4273-4284, 2015
1112015
Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice
BSY Choi, N Daniel, VP Houde, A Ouellette, B Marcotte, TV Varin, C Vors, ...
Nature Communications 12 (1), 1-16, 2021
902021
Endotoxin mediated-iNOS induction causes insulin resistance via ONOO− induced tyrosine nitration of IRS-1 in skeletal muscle
G Pilon, A Charbonneau, PJ White, P Dallaire, M Perreault, S Kapur, ...
PloS one 5 (12), e15912, 2010
802010
Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart
JM Walejko, BA Christopher, SB Crown, GF Zhang, A Pickar-Oliver, ...
Nature Communications 12 (1), 1680, 2021
772021
Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion
PJ White, AL Lapworth, RW McGarrah, LC Kwee, SB Crown, O Ilkayeva, ...
Cell Reports 33 (6), 108375, 2020
692020
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