| Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 6375 | 2018 |
| p53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa A Villunger, EM Michalak, L Coultas, F Mullauer, G Böck, ... Science 302 (5647), 1036-1038, 2003 | 1653 | 2003 |
| LDHA-associated lactic acid production blunts tumor immunosurveillance by T and NK cells A Brand, K Singer, GE Koehl, M Kolitzus, G Schoenhammer, A Thiel, ... Cell metabolism 24 (5), 657-671, 2016 | 1561 | 2016 |
| Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 L Galluzzi, BS Pedro, I Vitale, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 22 (1), 58-73, 2015 | 1240 | 2015 |
| Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis H Puthalakath, A Villunger, LA O'Reilly, JG Beaumont, L Coultas, ... Science 293 (5536), 1829-1832, 2001 | 837 | 2001 |
| FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal H You, M Pellegrini, K Tsuchihara, K Yamamoto, G Hacker, M Erlacher, ... The Journal of experimental medicine 203 (7), 1657-1663, 2006 | 506 | 2006 |
| Bcl2 family proteins in carcinogenesis and the treatment of cancer A Frenzel, F Grespi, W Chmelewskij, A Villunger Apoptosis 14, 584-596, 2009 | 457 | 2009 |
| Signalling strength determines proapoptotic functions of STING MF Gulen, U Koch, SM Haag, F Schuler, L Apetoh, A Villunger, F Radtke, ... Nature communications 8 (1), 427, 2017 | 441 | 2017 |
| Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic J Kuroda, H Puthalakath, MS Cragg, PN Kelly, P Bouillet, DCS Huang, ... Proceedings of the National Academy of Sciences 103 (40), 14907-14912, 2006 | 388 | 2006 |
| Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-xL DCS Huang, M Hahne, M Schroeter, K Frei, A Fontana, A Villunger, ... Proceedings of the National Academy of Sciences 96 (26), 14871-14876, 1999 | 385 | 1999 |
| BH3-only proteins Puma and Bim are rate-limiting for γ-radiation–and glucocorticoid-induced apoptosis of lymphoid cells in vivo M Erlacher, EM Michalak, PN Kelly, V Labi, H Niederegger, L Coultas, ... Blood 106 (13), 4131-4138, 2005 | 351 | 2005 |
| Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy TT Tan, K Degenhardt, DA Nelson, B Beaudoin, W Nieves-Neira, ... Cancer cell 7 (3), 227-238, 2005 | 348 | 2005 |
| Noxa: at the tip of the balance between life and death C Ploner, R Kofler, A Villunger Oncogene 27 (1), S84-S92, 2008 | 344 | 2008 |
| Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci E Melum, A Franke, C Schramm, TJ Weismüller, DN Gotthardt, FA Offner, ... Nature genetics 43 (1), 17-19, 2011 | 298 | 2011 |
| Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction M Erlacher, V Labi, C Manzl, G Böck, A Tzankov, G Häcker, E Michalak, ... The Journal of experimental medicine 203 (13), 2939-2951, 2006 | 273 | 2006 |
| p14–MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis D Teis, N Taub, R Kurzbauer, D Hilber, ME de Araujo, M Erlacher, ... Journal of Cell Biology 175 (6), 861-868, 2006 | 256 | 2006 |
| In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute EM Michalak, A Villunger, JM Adams, A Strasser Cell Death & Differentiation 15 (6), 1019-1029, 2008 | 249 | 2008 |
| How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? A Olsson, C Manzl, A Strasser, A Villunger Cell Death & Differentiation 14 (9), 1561-1575, 2007 | 245 | 2007 |
| Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy? V Labi, F Grespi, F Baumgartner, A Villunger Cell Death & Differentiation 15 (6), 977-987, 2008 | 215 | 2008 |
| The PIDDosome activates p53 in response to supernumerary centrosomes LL Fava, F Schuler, V Sladky, MD Haschka, C Soratroi, L Eiterer, ... Genes & development 31 (1), 34-45, 2017 | 209 | 2017 |
Greil-rProfessor of Medicine, Paracelsus Medical University SalzburgAdresă de e-mail confirmată pe salk.at
