| Systematic immunotherapy target discovery using genome-scale in vivo CRISPR screens in CD8 T cells MB Dong, G Wang, RD Chow, L Ye, L Zhu, X Dai, JJ Park, HR Kim, ... Cell 178 (5), 1189-1204. e23, 2019 | 283 | 2019 |
| AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma RD Chow, CD Guzman, G Wang, F Schmidt, MW Youngblood, L Ye, ... Nature neuroscience 20 (10), 1329-1341, 2017 | 247 | 2017 |
| Poly (ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-κB upon TLR4 stimulation M Zerfaoui, Y Errami, AS Naura, Y Suzuki, H Kim, J Ju, T Liu, CP Hans, ... The Journal of Immunology 185 (3), 1894-1902, 2010 | 177 | 2010 |
| In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma L Ye, JJ Park, MB Dong, Q Yang, RD Chow, L Peng, Y Du, J Guo, X Dai, ... Nature biotechnology 37 (11), 1302-1313, 2019 | 172 | 2019 |
| One-step generation of modular CAR-T cells with AAV–Cpf1 X Dai, JJ Park, Y Du, HR Kim, G Wang, Y Errami, S Chen Nature Methods 16 (3), 247-254, 2019 | 159 | 2019 |
| A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy L Ye, JJ Park, L Peng, Q Yang, RD Chow, MB Dong, SZ Lam, J Guo, ... Cell metabolism 34 (4), 595-614. e14, 2022 | 126 | 2022 |
| The poly (ADP-ribose) polymerases (PARPs): new roles in intracellular transport ZY Abd Elmageed, AS Naura, Y Errami, M Zerfaoui Cellular signalling 24 (1), 1-8, 2012 | 112 | 2012 |
| Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity G Wang, RD Chow, Z Bai, L Zhu, Y Errami, X Dai, MB Dong, L Ye, ... Nature Immunology 20 (11), 1494-1505, 2019 | 109 | 2019 |
| CRISPR-GEMM pooled mutagenic screening identifies KMT2D as a major modulator of immune checkpoint blockade G Wang, RD Chow, L Zhu, Z Bai, L Ye, F Zhang, PA Renauer, MB Dong, ... Cancer discovery 10 (12), 1912-1933, 2020 | 105 | 2020 |
| Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly (ADP-ribose) polymerase-regulated DNAS1L3, an endoplasmic … Y Errami, AS Naura, H Kim, J Ju, Y Suzuki, AH El-Bahrawy, MA Ghonim, ... Journal of Biological Chemistry 288 (5), 3460-3468, 2013 | 87 | 2013 |
| Requirement for inducible nitric oxide synthase in chronic allergen exposure-induced pulmonary fibrosis but not inflammation AS Naura, M Zerfaoui, H Kim, ZY Abd Elmageed, PC Rodriguez, CP Hans, ... The Journal of immunology 185 (5), 3076-3085, 2010 | 81 | 2010 |
| Cordycepin blocks lung injury-associated inflammation and promotes BRCA1-deficient breast cancer cell killing by effectively inhibiting PARP H Kim, AS Naura, Y Errami, J Ju, AH Boulares Molecular medicine 17, 893-900, 2011 | 68 | 2011 |
| High-fat diet induces lung remodeling in ApoE-deficient mice: an association with an increase in circulatory and lung inflammatory factors AS Naura, CP Hans, M Zerfaoui, Y Errami, J Ju, H Kim, K Matrougui, ... Laboratory investigation 89 (11), 1243-1251, 2009 | 66 | 2009 |
| PARP‐1 deficiency blocks IL‐5 expression through calpain‐dependent degradation of STAT‐6 in a murine asthma model R Datta, AS Naura, M Zerfaoui, Y Errami, M Oumouna, H Kim, J Ju, ... Allergy 66 (7), 853-861, 2011 | 65 | 2011 |
| In vivo profiling of metastatic double knockouts through CRISPR–Cpf1 screens RD Chow, G Wang, L Ye, A Codina, HR Kim, L Shen, MB Dong, Y Errami, ... Nature methods 16 (5), 405-408, 2019 | 62 | 2019 |
| Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer MA Ghonim, SV Ibba, AF Tarhuni, Y Errami, HH Luu, MJ Dean, ... Journal for immunotherapy of cancer 9 (1), e001643, 2021 | 58 | 2021 |
| Phosphorylation of p50 NF-κB at a single serine residue by DNA-dependent protein kinase is critical for VCAM-1 expression upon TNF treatment J Ju, AS Naura, Y Errami, M Zerfaoui, H Kim, JG Kim, ZY Abd Elmageed, ... Journal of Biological Chemistry 285 (52), 41152-41160, 2010 | 57 | 2010 |
| Reciprocal regulation of iNOS and PARP-1 during allergen-induced eosinophilia AS Naura, R Datta, CP Hans, M Zerfaoui, BM Rezk, Y Errami, M Oumouna, ... European Respiratory Journal 33 (2), 252-262, 2009 | 49 | 2009 |
| Effects of PARP-1 deficiency on airway inflammatory cell recruitment in response to LPS or TNF: differential effects on CXCR2 ligands and Duffy antigen receptor for chemokines M Zerfaoui, AS Naura, Y Errami, CP Hans, BM Rezk, J Park, W Elsegeiny, ... Journal of leukocyte biology 86 (6), 1385-1392, 2009 | 38 | 2009 |
| Minocycline blocks asthma-associated inflammation in part by interfering with the T cell receptor-nuclear factor κB-GATA-3-IL-4 axis without a prominent effect on poly (ADP … AS Naura, H Kim, J Ju, PC Rodriguez, J Jordan, AD Catling, BM Rezk, ... Journal of Biological Chemistry 288 (3), 1458-1468, 2013 | 29 | 2013 |
Amarjit S NauraDept. of Biochemistry, Panjab UniversityAdresă de e-mail confirmată pe pu.ac.in