| Antitumor activity of abnormal cannabidiol and its analog O-1602 in taxol-resistant preclinical models of breast cancer A Tomko, L O’Leary, H Trask, JC Achenbach, SR Hall, KB Goralski, ... Frontiers in pharmacology 10, 1124, 2019 | 52 | 2019 |
| Small molecule drug discovery for neglected tropical snakebite RH Clare, SR Hall, RN Patel, NR Casewell Trends in pharmacological sciences 42 (5), 340-353, 2021 | 51 | 2021 |
| Jadomycin breast cancer cytotoxicity is mediated by a copper‐dependent, reactive oxygen species–inducing mechanism SR Hall, HL Blundon, MA Ladda, AW Robertson, CF Martinez‐Farina, ... Pharmacology Research & Perspectives 3 (2), e00110, 2015 | 38 | 2015 |
| Jadomycins are cytotoxic to ABCB1-, ABCC1-, and ABCG2-overexpressing MCF7 breast cancer cells ME Issa, SR Hall, SN Dupuis, CL Graham, DL Jakeman, KB Goralski Anti-Cancer Drugs 25 (3), 255-269, 2014 | 37 | 2014 |
| Jadomycins inhibit type II topoisomerases and promote DNA damage and apoptosis in multidrug-resistant triple-negative breast cancer cells SR Hall, J Toulany, LG Bennett, CF Martinez-Farina, AW Robertson, ... The Journal of pharmacology and experimental therapeutics 363 (2), 196-210, 2017 | 27 | 2017 |
| Decitabine response in breast cancer requires efficient drug processing and is not limited by multidrug resistance ML Dahn, BM Cruickshank, AJ Jackson, C Dean, RW Holloway, SR Hall, ... Molecular cancer therapeutics 19 (5), 1110-1122, 2020 | 26 | 2020 |
| Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms SR Hall, SA Rasmussen, E Crittenden, CA Dawson, KE Bartlett, ... Nature communications 14 (1), 7812, 2023 | 25 | 2023 |
| In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus SK Menzies, RH Clare, C Xie, A Westhorpe, SR Hall, RJ Edge, J Alsolaiss, ... Toxicon: X 14, 100118, 2022 | 21 | 2022 |
| Exploring the utility of recombinant snake venom serine protease toxins as immunogens for generating experimental snakebite antivenoms N Alomran, P Blundell, J Alsolaiss, E Crittenden, S Ainsworth, CA Dawson, ... Toxins 14 (7), 443, 2022 | 17 | 2022 |
| Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib KE Bartlett, SR Hall, SA Rasmussen, E Crittenden, CA Dawson, ... Proceedings of the National Academy of Sciences 121 (19), e2315597121, 2024 | 12 | 2024 |
| Post Polyketide Synthase Carbon–Carbon Bond Formation in Type-II PKS-Derived Natural Products from Streptomyces venezuelae AW Robertson, JM MacLeod, LW MacIntyre, SM Forget, SR Hall, ... The Journal of Organic Chemistry 83 (4), 1876-1890, 2018 | 12 | 2018 |
| Two snakebite antivenoms have potential to reduce Eswatini’s dependency upon a single, increasingly unavailable product: Results of preclinical efficacy testing SK Menzies, T Litschka-Koen, RJ Edge, J Alsolaiss, E Crittenden, SR Hall, ... PLoS neglected tropical diseases 16 (9), e0010496, 2022 | 11 | 2022 |
| Physiological constraints dictate toxin spatial heterogeneity in snake venom glands TD Kazandjian, BR Hamilton, SD Robinson, SR Hall, KE Bartlett, ... BMC biology 20 (1), 148, 2022 | 10 | 2022 |
| Proteomics and histological assessment of an organotypic model of human skin following exposure to Naja nigricollis venom S Ahmadi, ST Pachis, K Kalogeropoulos, F McGeoghan, V Canbay, ... Toxicon 220, 106955, 2022 | 8 | 2022 |
| Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition SK Menzies, CA Dawson, E Crittenden, RJ Edge, SR Hall, J Alsolaiss, ... Scientific Reports 12 (1), 11328, 2022 | 7 | 2022 |
| Isolation of a jadomycin incorporating l-ornithine, analysis of antimicrobial activity and jadomycin reactive oxygen species (ROS) generation in MDA-MB-231 breast … SM Forget, AW Robertson, SR Hall, JM MacLeod, DP Overy, RG Kerr, ... The Journal of Antibiotics 71 (8), 722-730, 2018 | 7 | 2018 |
| Pilot study of jadomycin B pharmacokinetics and anti-tumoral effects in zebrafish larvae and mouse breast cancer xenograft models BT McKeown, NJ Relja, SR Hall, S Gebremeskel, JM MacLeod, ... Canadian Journal of Physiology and Pharmacology 100 (11), 1065-1076, 2022 | 6 | 2022 |
| Molecular dissection of cobra venom highlights heparinoids as an antidote for spitting cobra envenoming TY Du, SR Hall, F Chung, S Kurdyukov, E Crittenden, K Patel, CA Dawson, ... Science Translational Medicine 16 (756), eadk4802, 2024 | 4 | 2024 |
| Intraspecific venom variation in the medically important puff adder (Bitis arietans): Comparative venom gland transcriptomics, in vitro venom activity and … CA Dawson, KE Bartlett, MC Wilkinson, S Ainsworth, LO Albulescu, ... PLOS Neglected Tropical Diseases 18 (10), e0012570, 2024 | 3 | 2024 |
| Machine-learning guided venom induced dermonecrosis analysis tooL: VIDAL W Laprade, KE Bartlett, CR Christensen, TD Kazandjian, RN Patel, ... Scientific Reports 13 (1), 21662, 2023 | 3 | 2023 |
Mark E. IssaMassachusetts General Hospital & Harvard Medical SchoolAdresă de e-mail confirmată pe mgh.harvard.edu