Native ion mobility-mass spectrometry reveals the formation of β-barrel shaped amyloid-β hexamers in a membrane-mimicking environment N Österlund, R Moons, LL Ilag, F Sobott, A Gräslund Journal of the American Chemical Society 141 (26), 10440-10450, 2019 | 119 | 2019 |
Alzheimer’s disease and cigarette smoke components: Effects of nicotine, PAHs, and Cd (II), Cr (III), Pb (II), Pb (IV) ions on amyloid-β peptide aggregation C Wallin, SB Sholts, N Österlund, J Luo, J Jarvet, PM Roos, L Ilag, ... Scientific Reports 7 (1), 14423, 2017 | 104 | 2017 |
Metal binding to the amyloid-β peptides in the presence of biomembranes: Potential mechanisms of cell toxicity SKTS Wärmländer, N Österlund, C Wallin, J Wu, J Luo, A Tiiman, J Jarvet, ... JBIC Journal of Biological Inorganic Chemistry 24, 1189-1196, 2019 | 63 | 2019 |
Amyloid-β peptide interactions with amphiphilic surfactants: Electrostatic and hydrophobic effects N Osterlund, YS Kulkarni, AD Misiaszek, C Wallin, DM Krüger, Q Liao, ... ACS chemical neuroscience 9 (7), 1680-1692, 2018 | 60* | 2018 |
Membrane-mimetic systems for biophysical studies of the amyloid-β peptide N Österlund, J Luo, SKTS Wärmländer, A Gräslund Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (5), 492-501, 2019 | 51 | 2019 |
Amyloid-β oligomers are captured by the DNAJB6 chaperone: Direct detection of interactions that can prevent primary nucleation N Österlund, M Lundqvist, LL Ilag, A Gräslund, C Emanuelsson Journal of Biological Chemistry 295 (24), 8135-8144, 2020 | 45 | 2020 |
A hairpin motif in the amyloid-β peptide is important for formation of disease-related oligomers M Khaled, I Rönnbäck, LL Ilag, A Gräslund, B Strodel, N Österlund Journal of the American Chemical Society 145 (33), 18340-18354, 2023 | 36 | 2023 |
Solvent-assisted paper spray ionization mass spectrometry (SAPSI-MS) for the analysis of biomolecules and biofluids N Riboni, A Quaranta, HV Motwani, N Österlund, A Gräslund, F Bianchi, ... Scientific Reports 9 (1), 10296, 2019 | 23 | 2019 |
Gas-Phase Collisions with Trimethylamine-N-Oxide Enable Activation-Controlled Protein Ion Charge Reduction M Kaldmäe, N Österlund, D Lianoudaki, C Sahin, P Bergman, T Nyman, ... Journal of The American Society for Mass Spectrometry 30 (8), 1385-1388, 2019 | 23 | 2019 |
Charge engineering reveals the roles of ionizable side chains in electrospray ionization mass spectrometry ML Abramsson, C Sahin, JTS Hopper, RMM Branca, J Danielsson, M Xu, ... JACS Au 1 (12), 2385-2393, 2021 | 21 | 2021 |
The amyloid-inhibiting NCAM-PrP peptide targets Aβ peptide aggregation in membrane-mimetic environments S Król, N Österlund, F Vosough, J Jarvet, S Wärmländer, A Barth, LL Ilag, ... Iscience 24 (8), 2021 | 17 | 2021 |
Identifying the role of co-aggregation of Alzheimer’s amyloid-β with amorphous protein aggregates of non-amyloid proteins J Wu, N Österlund, H Wang, R Sternke-Hoffmann, H Pupart, LL Ilag, ... Cell Reports Physical Science 3 (9), 2022 | 15 | 2022 |
Structural basis for dityrosine-mediated inhibition of α-synuclein fibrillization C Sahin, EC Østerlund, N Österlund, J Costeira-Paulo, JN Pedersen, ... Journal of the American Chemical Society 144 (27), 11949-11954, 2022 | 15 | 2022 |
Cell-penetrating peptides with unexpected anti-amyloid properties N Österlund, SKTS Wärmländer, A Gräslund Pharmaceutics 14 (4), 823, 2022 | 13 | 2022 |
Mass spectrometry and machine learning reveal determinants of client recognition by antiamyloid chaperones N Österlund, T Vosselman, A Leppert, A Gräslund, H Jörnvall, LL Ilag, ... Molecular & Cellular Proteomics 21 (10), 2022 | 9 | 2022 |
Ion mobility-mass spectrometry shows stepwise protein unfolding under alkaline conditions C Sahin, N Österlund, A Leppert, J Johansson, EG Marklund, ... Chemical Communications 57 (12), 1450-1453, 2021 | 8 | 2021 |
A “spindle and thread” mechanism unblocks p53 translation by modulating N-terminal disorder M Kaldmäe, T Vosselman, X Zhong, D Lama, G Chen, M Saluri, ... Structure 30 (5), 733-742. e7, 2022 | 7 | 2022 |
Oligomer Dynamics of LL‐37 Truncated Fragments Probed by α‐Hemolysin Pore and Molecular Simulations C Liu, A Henning‐Knechtel, N Österlund, J Wu, G Wang, RAO Gräslund, ... Small 19 (37), 2206232, 2023 | 6 | 2023 |
The C-terminal domain of the antiamyloid chaperone DNAJB6 binds to amyloid-β peptide fibrils and inhibits secondary nucleation N Österlund, R Frankel, A Carlsson, D Thacker, M Karlsson, V Matus, ... Journal of Biological Chemistry 299 (11), 2023 | 5 | 2023 |
Role of hydrophobic residues for the gaseous formation of helical motifs L Liu, X Dong, Y Liu, N Österlund, A Gräslund, P Carloni, J Li Chemical Communications 55 (35), 5147-5150, 2019 | 5 | 2019 |