The upstreams and downstreams of H3K79 methylation by DOT1L H Vlaming, F van Leeuwen Chromosoma 125 (4), 593-605, 2016 | 115 | 2016 |
Yeast PP4 Interacts with ATR Homolog Ddc2-Mec1 and Regulates Checkpoint Signaling N Hustedt, A Seeber, R Sack, M Tsai-Pflugfelder, B Bhullar, H Vlaming, ... Molecular cell 57 (2), 273-289, 2015 | 84 | 2015 |
HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis CD Zimberlin, C Lancini, R Sno, SL Rosekrans, CM McLean, H Vlaming, ... The FASEB Journal 29 (5), 2070-2080, 2015 | 53 | 2015 |
Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo H Vlaming, T van Welsem, EL de Graaf, D Ontoso, AFM Altelaar, ... EMBO reports 15 (10), 1077-1084, 2014 | 50 | 2014 |
The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8+ T cells EM Kwesi-Maliepaard, MA Aslam, MF Alemdehy, T van den Brand, ... Proceedings of the National Academy of Sciences 117 (34), 20706-20716, 2020 | 43 | 2020 |
Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism T van Welsem, T Korthout, R Ekkebus, D Morais, TM Molenaar, ... Nucleic acids research 46 (21), 11251-11261, 2018 | 39 | 2018 |
Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential H Vlaming, CA Mimoso, AR Field, BJE Martin, K Adelman Nature Structural & Molecular Biology 29, 613–620, 2022 | 38 | 2022 |
Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma H Vlaming, CM McLean, T Korthout, MF Alemdehy, S Hendriks, C Lancini, ... The EMBO journal 38 (14), e101564, 2019 | 38 | 2019 |
Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1 H Vlaming, TM Molenaar, T van Welsem, DW Poramba-Liyanage, ... eLife 5, e18919, 2016 | 33 | 2016 |
Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties. IJ Stulemeijer, D De Vos, K Van Harten, OK Joshi, O Blomberg, ... Scientific reports 5, 9824-9824, 2015 | 28 | 2015 |
Crosstalk between aging and the epigenome H Vlaming, F van Leeuwen Epigenomics 4 (1), 5-7, 2012 | 14 | 2012 |
Strength is in engagement: The rise of an online scientific community during the COVID‐19 pandemic CE Cucinotta, BJE Martin, M Noé González, P Raman, VB Teif, H Vlaming EMBO reports 22 (5), e52612, 2021 | 7 | 2021 |
Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies L Kollenstart, SC van der Horst, K Vreeken, GMC Janssen, F Martino, ... Scientific reports 11 (1), 1-17, 2021 | 3 | 2021 |
Modeling Distributive Histone Modification by Dot1 Methyltransferases: From Mechanism to Biological Insights. D De Vos, H Vlaming, BM Bakker, F Van Leeuwen Epigenetics and Systems Biology, 117–141, 2017 | 2 | 2017 |
DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro EM Kwesi-Maliepaard, M Malik, T Van Welsem, R Van Doorn, ... Frontiers in Genetics, 3178, 2022 | 1 | 2022 |
Connecting the dots: Delineating the regulation of H3K79 methylation by Dot1 H Vlaming Universiteit van Amsterdam, 2017 | | 2017 |