| Metformin improves healthspan and lifespan in mice A Martin-Montalvo, EM Mercken, SJ Mitchell, HH Palacios, PL Mote, ... Nature communications 4 (1), 2192, 2013 | 1556 | 2013 |
| Effects of sex, strain, and energy intake on hallmarks of aging in mice SJ Mitchell, J Madrigal-Matute, M Scheibye-Knudsen, E Fang, M Aon, ... Cell metabolism 23 (6), 1093-1112, 2016 | 455 | 2016 |
| The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet SJ Mitchell, A Martin-Montalvo, EM Mercken, HH Palacios, TM Ward, ... Cell reports 6 (5), 836-843, 2014 | 447 | 2014 |
| Osteocalcin signaling in myofibers is necessary and sufficient for optimum adaptation to exercise P Mera, K Laue, M Ferron, C Confavreux, J Wei, M Galán-Díez, ... Cell metabolism 23 (6), 1078-1092, 2016 | 441 | 2016 |
| Loss of epigenetic information as a cause of mammalian aging JH Yang, M Hayano, PT Griffin, JA Amorim, MS Bonkowski, ... Cell 186 (2), 305-326. e27, 2023 | 403 | 2023 |
| A high-fat diet and NAD+ activate Sirt1 to rescue premature aging in cockayne syndrome M Scheibye-Knudsen, SJ Mitchell, EF Fang, T Iyama, T Ward, J Wang, ... Cell metabolism 20 (5), 840-855, 2014 | 380 | 2014 |
| Animal models of aging research: implications for human aging and age-related diseases SJ Mitchell, M Scheibye-Knudsen, DL Longo, R de Cabo Annu. Rev. Anim. Biosci. 3 (1), 283-303, 2015 | 362 | 2015 |
| Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice SJ Mitchell, M Bernier, MA Aon, S Cortassa, EY Kim, EF Fang, ... Cell metabolism 27 (3), 667-676. e4, 2018 | 340 | 2018 |
| Selective persulfide detection reveals evolutionarily conserved antiaging effects of S-sulfhydration J Zivanovic, E Kouroussis, JB Kohl, B Adhikari, B Bursac, S Schott-Roux, ... Cell metabolism 30 (6), 1152-1170. e13, 2019 | 319 | 2019 |
| Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway H Ashrafian, G Czibik, M Bellahcene, D Aksentijević, AC Smith, ... Cell metabolism 15 (3), 361-371, 2012 | 318 | 2012 |
| Daily fasting improves health and survival in male mice independent of diet composition and calories SJ Mitchell, M Bernier, JA Mattison, MA Aon, TA Kaiser, RM Anson, ... Cell metabolism 29 (1), 221-228. e3, 2019 | 303 | 2019 |
| The assessment of frailty in older people in acute care SN Hilmer, V Perera, S Mitchell, BP Murnion, J Dent, B Bajorek, ... Australasian journal on ageing 28 (4), 182-188, 2009 | 271 | 2009 |
| SRT 2104 extends survival of male mice on a standard diet and preserves bone and muscle mass EM Mercken, SJ Mitchell, A Martin‐Montalvo, RK Minor, M Almeida, ... Aging Cell 13 (5), 787-796, 2014 | 262 | 2014 |
| Dietary protein to carbohydrate ratio and caloric restriction: comparing metabolic outcomes in mice SM Solon-Biet, SJ Mitchell, SCP Coogan, VC Cogger, R Gokarn, ... Cell reports 11 (10), 1529-1534, 2015 | 230 | 2015 |
| The impact of low-protein high-carbohydrate diets on aging and lifespan DG Le Couteur, S Solon-Biet, VC Cogger, SJ Mitchell, A Senior, ... Cellular and Molecular Life Sciences 73, 1237-1252, 2016 | 217 | 2016 |
| Macronutrients and caloric intake in health and longevity SM Solon-Biet, SJ Mitchell, R de Cabo, D Raubenheimer, DG Le Couteur, ... The Journal of endocrinology 226 (1), R17, 2015 | 172 | 2015 |
| RAP1 protects from obesity through its extratelomeric role regulating gene expression P Martínez, G Gómez-López, F García, E Mercken, S Mitchell, JM Flores, ... Cell reports 3 (6), 2059-2074, 2013 | 136 | 2013 |
| Impact of longevity interventions on a validated mouse clinical frailty index AE Kane, SN Hilmer, D Boyer, K Gavin, D Nines, SE Howlett, R de Cabo, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2016 | 135 | 2016 |
| Age and life expectancy clocks based on machine learning analysis of mouse frailty MB Schultz, AE Kane, SJ Mitchell, MR MacArthur, E Warner, DS Vogel, ... Nature communications 11 (1), 4618, 2020 | 116 | 2020 |
| Untangling determinants of enhanced health and lifespan through a multi-omics approach in mice MA Aon, M Bernier, SJ Mitchell, C Di Germanio, JA Mattison, MR Ehrlich, ... Cell metabolism 32 (1), 100-116. e4, 2020 | 114 | 2020 |