Autoantibodies against type I IFNs in patients with life-threatening COVID-19 P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), eabd4585, 2020 | 2757 | 2020 |
Guidelines for the use of flow cytometry and cell sorting in immunological studies A Cossarizza, HD Chang, A Radbruch, A Acs, D Adam, S Adam‐Klages, ... European journal of immunology 49 (10), 1457-1973, 2019 | 1990 | 2019 |
Positional cloning of the APECED gene K Nagamine, P Peterson, HS Scott, J Kudoh, S Minoshima, M Heino, ... Nature genetics 17 (4), 393-398, 1997 | 1668 | 1997 |
A dynamic COVID-19 immune signature includes associations with poor prognosis AG Laing, A Lorenc, I Del Molino Del Barrio, A Das, M Fish, L Monin, ... Nature medicine 26 (10), 1623-1635, 2020 | 1016 | 2020 |
Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 848 | 2021 |
Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines K Kisand, AS Bøe Wolff, KT Podkrajšek, L Tserel, M Link, KV Kisand, ... Journal of Experimental Medicine 207 (2), 299-308, 2010 | 750 | 2010 |
The transcriptional landscape of age in human peripheral blood MJ Peters, R Joehanes, LC Pilling, C Schurmann, KN Conneely, J Powell, ... Nature communications 6 (1), 8570, 2015 | 681 | 2015 |
Dynamics of antibody response to BNT162b2 vaccine after six months: a longitudinal prospective study P Naaber, L Tserel, K Kangro, E Sepp, V Jürjenson, A Adamson, ... The Lancet Regional Health–Europe 10, 2021 | 617 | 2021 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 542 | 2021 |
Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1 A Meager, K Visvalingam, P Peterson, K Möll, A Murumägi, K Krohn, ... PLoS medicine 3 (7), e289, 2006 | 507 | 2006 |
Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study GI Rice, GMA Forte, M Szynkiewicz, DS Chase, A Aeby, MS Abdel-Hamid, ... The lancet neurology 12 (12), 1159-1169, 2013 | 465 | 2013 |
Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases AL Cardoso, A Fernandes, JA Aguilar-Pimentel, MH de Angelis, ... Ageing research reviews 47, 214-277, 2018 | 449 | 2018 |
Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22. 3, related to the cytosine-5-methyltransferase 3 gene family U Aapola, K Shibuya, HS Scott, J Ollila, M Vihinen, M Heino, A Shintani, ... Genomics 65 (3), 293-298, 2000 | 423 | 2000 |
Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis KE Webster, MK O'Bryan, S Fletcher, PE Crewther, U Aapola, J Craig, ... Proceedings of the National Academy of Sciences 102 (11), 4068-4073, 2005 | 362 | 2005 |
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla M Heino, P Peterson, J Kudoh, K Nagamine, A Lagerstedt, V Ovod, ... Biochemical and biophysical research communications 257 (3), 821-825, 1999 | 350 | 1999 |
Whole-genome sequencing reveals host factors underlying critical COVID-19 A Kousathanas, E Pairo-Castineira, K Rawlik, A Stuckey, CA Odhams, ... Nature 607 (7917), 97-103, 2022 | 310 | 2022 |
Transcriptional regulation by AIRE: molecular mechanisms of central tolerance P Peterson, T Org, A Rebane Nature Reviews Immunology 8 (12), 948-957, 2008 | 304 | 2008 |
A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients MC Rosatelli, A Meloni, A Meloni, M Devoto, A Cao, HS Scott, P Peterson, ... Human genetics 103, 428-434, 1998 | 298 | 1998 |
The autoimmune regulator PHD finger binds to non‐methylated histone H3K4 to activate gene expression T Org, F Chignola, C Hetenyi, M Gaetani, A Rebane, I Liiv, U Maran, ... EMBO reports 9 (4), 370-376, 2008 | 289 | 2008 |
AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies S Meyer, M Woodward, C Hertel, P Vlaicu, Y Haque, J Kärner, A Macagno, ... Cell 166 (3), 582-595, 2016 | 288 | 2016 |