Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors O Naujok, J Lentes, U Diekmann, C Davenport, S Lenzen BMC research notes 7, 1-8, 2014 | 139 | 2014 |
The generation of definitive endoderm from human embryonic stem cells is initially independent from activin A but requires canonical Wnt-signaling O Naujok, U Diekmann, S Lenzen Stem Cell Reviews and Reports 10, 480-493, 2014 | 80 | 2014 |
Anterior–posterior patterning of definitive endoderm generated from human embryonic stem cells depends on the differential signaling of retinoic acid, Wnt-, and BMP-signaling C Davenport, U Diekmann, I Budde, N Detering, O Naujok Stem Cells 34 (11), 2635-2647, 2016 | 75 | 2016 |
Reversal of diabetes through gene therapy of diabetic rats by hepatic insulin expression via lentiviral transduction M Elsner, T Terbish, A Jörns, O Naujok, D Wedekind, HJ Hedrich, ... Molecular Therapy 20 (5), 918-926, 2012 | 65 | 2012 |
Insulin-producing surrogate β-cells from embryonic stem cells: are we there yet? O Naujok, C Burns, PM Jones, S Lenzen Molecular Therapy 19 (10), 1759-1768, 2011 | 62 | 2011 |
40th EASD Annual Meeting of the European Association for the Study of Diabetes: Munich, Germany, 5–9 September 2004 M Veitenhansl, K Stegner, FX Hierl, C Dieterle, H Feldmeier, B Gutt, ... Diabetologia 47, A1-A464, 2004 | 56 | 2004 |
Overexpression of the antioxidant enzyme catalase does not interfere with the glucose responsiveness of insulin-secreting INS-1E cells and rat islets S Lortz, E Gurgul-Convey, O Naujok, S Lenzen Diabetologia 56, 774-782, 2013 | 51 | 2013 |
Selective removal of undifferentiated embryonic stem cells from differentiation cultures through HSV1 thymidine kinase and ganciclovir treatment O Naujok, J Kaldrack, T Taivankhuu, A Jörns, S Lenzen Stem cell reviews and reports 6, 450-461, 2010 | 49 | 2010 |
Changes in gene expression and morphology of mouse embryonic stem cells on differentiation into insulin‐producing cells in vitro and in vivo O Naujok, F Francini, S Picton, CJ Bailey, S Lenzen, A Jörns Diabetes/metabolism research and reviews 25 (5), 464-476, 2009 | 36 | 2009 |
A reliable and efficient protocol for human pluripotent stem cell differentiation into the definitive endoderm based on dispersed single cells U Diekmann, S Lenzen, O Naujok Stem cells and development 24 (2), 190-204, 2015 | 34 | 2015 |
A new experimental protocol for preferential differentiation of mouse embryonic stem cells into insulin-producing cells O Naujok, F Francini, S Picton, A Jörns, CJ Bailey, S Lenzen Cell transplantation 17 (10-11), 1231-1242, 2008 | 31 | 2008 |
miRNome profiling of purified endoderm and mesoderm differentiated from hESCs reveals functions of miR-483-3p and miR-1263 for cell-fate decisions D Ishikawa, U Diekmann, J Fiedler, A Just, T Thum, S Lenzen, O Naujok Stem cell reports 9 (5), 1588-1603, 2017 | 26 | 2017 |
An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin‐19‐positive population of insulin‐producing cells O Naujok, F Francini, A Jörns, S Lenzen Cell Proliferation 41 (4), 607-624, 2008 | 25 | 2008 |
Chemically-defined, xeno-free, scalable production of hPSC-derived definitive endoderm aggregates with multi-lineage differentiation potential A Sahabian, M Sgodda, O Naujok, R Dettmer, J Dahlmann, F Manstein, ... Cells 8 (12), 1571, 2019 | 24 | 2019 |
A critical re-evaluation of CD24-positivity of human embryonic stem cells differentiated into pancreatic progenitors O Naujok, S Lenzen Stem Cell Reviews and Reports 8, 779-791, 2012 | 24 | 2012 |
Coaxial alginate hydrogels: from self-assembled 3D cellular constructs to long-term storage O Gryshkov, V Mutsenko, D Tarusin, D Khayyat, O Naujok, E Riabchenko, ... International journal of molecular sciences 22 (6), 3096, 2021 | 23 | 2021 |
FGF2 inhibits early pancreatic lineage specification during differentiation of human embryonic stem cells R Dettmer, K Cirksena, J Münchhoff, J Kresse, U Diekmann, I Niwolik, ... Cells 9 (9), 1927, 2020 | 20 | 2020 |
Proinflammatory cytokines induce rapid, NO-independent apoptosis, expression of chemotactic mediators and interleukin-32 secretion in human pluripotent stem cell-derived beta cells R Dettmer, I Niwolik, K Cirksena, T Yoshimoto, Y Tang, I Mehmeti, ... Diabetologia 65 (5), 829-843, 2022 | 19 | 2022 |
Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D culture U Diekmann, H Wolling, R Dettmer, I Niwolik, O Naujok, FFR Buettner Scientific Reports 9 (1), 996, 2019 | 19 | 2019 |
Embryonic stem cells of the non‐human primate Callithrix jacchus can be differentiated into definitive endoderm by Activin‐A but not IDE‐1/2 U Diekmann, O Naujok, R Blasczyk, T Müller Journal of tissue engineering and regenerative medicine 9 (4), 473-479, 2015 | 16 | 2015 |