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| Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 6363 | 2018 |
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| DRAM, a p53-induced modulator of autophagy, is critical for apoptosis D Crighton, S Wilkinson, J O'Prey, N Syed, P Smith, PR Harrison, ... Cell 126 (1), 121-134, 2006 | 1696 | 2006 |
| The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2 FJ Stott, S Bates, MC James, BB McConnell, M Starborg, S Brookes, ... The EMBO journal, 1998 | 1545 | 1998 |
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| p53 and metabolism KH Vousden, KM Ryan Nature Reviews Cancer 9 (10), 691-700, 2009 | 1205 | 2009 |
| Autophagy in major human diseases DJ Klionsky, G Petroni, RK Amaravadi, EH Baehrecke, A Ballabio, P Boya, ... The EMBO journal 40 (19), e108863, 2021 | 1141 | 2021 |
| Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal–epithelial transition factor (c-MET) kinase and anaplastic … JJ Cui, M Tran-Dubé, H Shen, M Nambu, PP Kung, M Pairish, L Jia, ... Journal of medicinal chemistry 54 (18), 6342-6363, 2011 | 1050 | 2011 |
| Regulation and function of the p53 tumor suppressor protein KM Ryan, AC Phillips, KH Vousden Current opinion in cell biology 13 (3), 332-337, 2001 | 1047 | 2001 |
| Role of NF-κB in p53-mediated programmed cell death KM Ryan, MK Ernst, NR Rice, KH Vousden Nature 404 (6780), 892-897, 2000 | 969 | 2000 |
| p53 status determines the role of autophagy in pancreatic tumour development MT Rosenfeldt, J O’Prey, JP Morton, C Nixon, G MacKay, A Mrowinska, ... Nature 504 (7479), 296-300, 2013 | 758 | 2013 |
| Autophagy and autophagy-related pathways in cancer J Debnath, N Gammoh, KM Ryan Nature reviews Molecular cell biology 24 (8), 560-575, 2023 | 643 | 2023 |
| Discovery of ketone-based covalent inhibitors of coronavirus 3CL proteases for the potential therapeutic treatment of COVID-19 RL Hoffman, RS Kania, MA Brothers, JF Davies, RA Ferre, KS Gajiwala, ... Journal of medicinal chemistry 63 (21), 12725-12747, 2020 | 489 | 2020 |
| Mitochondrial inner membrane permeabilisation enables mt DNA release during apoptosis JS Riley, G Quarato, C Cloix, J Lopez, J O'Prey, M Pearson, J Chapman, ... The EMBO journal 37 (17), e99238, 2018 | 452 | 2018 |
| Mannose impairs tumour growth and enhances chemotherapy PS Gonzalez, J O’Prey, S Cardaci, VJA Barthet, J Sakamaki, F Beaumatin, ... Nature 563 (7733), 719-723, 2018 | 404 | 2018 |
| The multiple roles of autophagy in cancer MT Rosenfeldt, KM Ryan Carcinogenesis 32 (7), 955-963, 2011 | 378 | 2011 |
| Induction of DNA synthesis and apoptosis are separable functions of E2F-1. AC Phillips, S Bates, KM Ryan, K Helin, KH Vousden Genes & development 11 (14), 1853-1863, 1997 | 336 | 1997 |
| PUMA-and Bax-induced autophagy contributes to apoptosis KS Yee, S Wilkinson, J James, KM Ryan, KH Vousden Cell Death & Differentiation 16 (8), 1135-1145, 2009 | 287 | 2009 |
| New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy JS Long, KM Ryan Oncogene 31 (49), 5045-5060, 2012 | 280 | 2012 |
