Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer K Joshi, MR de Massy, M Ismail, JL Reading, I Uddin, A Woolston, ... Nature medicine 25 (10), 1549-1559, 2019 | 187 | 2019 |
High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities JM Heather, M Ismail, T Oakes, B Chain Briefings in bioinformatics 19 (4), 554-565, 2018 | 120 | 2018 |
Quantitative characterization of the T cell receptor repertoire of naïve and memory subsets using an integrated experimental and computational pipeline which is robust … T Oakes, JM Heather, K Best, R Byng-Maddick, C Husovsky, M Ismail, ... Frontiers in immunology 8, 1267, 2017 | 116 | 2017 |
Benchmarking of T cell receptor repertoire profiling methods reveals large systematic biases P Barennes, V Quiniou, M Shugay, ES Egorov, AN Davydov, ... Nature biotechnology 39 (2), 236-245, 2021 | 111 | 2021 |
The T cell differentiation landscape is shaped by tumour mutations in lung cancer E Ghorani, JL Reading, JY Henry, MR Massy, R Rosenthal, V Turati, ... Nature cancer 1 (5), 546-561, 2020 | 100 | 2020 |
The naive T-cell receptor repertoire has an extremely broad distribution of clone sizes PC de Greef, T Oakes, B Gerritsen, M Ismail, JM Heather, R Hermsen, ... Elife 9, e49900, 2020 | 96 | 2020 |
Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment YNS Wong, K Joshi, P Khetrapal, M Ismail, JL Reading, MW Sunderland, ... Journal of Experimental Medicine 215 (11), 2748-2759, 2018 | 59 | 2018 |
The T cell response to the contact sensitizer paraphenylenediamine is characterized by a polyclonal diverse repertoire of antigen-specific receptors T Oakes, AL Popple, J Williams, K Best, JM Heather, M Ismail, G Maxwell, ... Frontiers in Immunology 8, 162, 2017 | 21 | 2017 |
Quantitative analysis of the T cell receptor repertoire I Uddin, A Woolston, T Peacock, K Joshi, M Ismail, T Ronel, C Husovsky, ... Methods in enzymology 629, 465-492, 2019 | 19 | 2019 |
Clinical testing of transcriptome-wide expression profiles in high-risk localized and metastatic prostate cancer starting androgen deprivation therapy: an ancillary study of … MA Parry, E Grist, L Mendes, P Dutey-Magni, A Sachdeva, C Brawley, ... Research Square, rs. 3. rs-2488586, 2023 | 12 | 2023 |
TRACERx consortium. Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer K Joshi, MR de Massy, M Ismail, JL Reading, I Uddin, A Woolston, ... Nat Med 25 (10), 1549-1559, 2019 | 8 | 2019 |
Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer A Kiviaho, SK Eerola, HML Kallio, MK Andersen, M Hoikka, AM Tiihonen, ... Nature Communications 15 (1), 9949, 2024 | 4 | 2024 |
Copy number architectures define treatment-mediated selection of lethal prostate cancer clones AMM Hasan, P Cremaschi, D Wetterskog, A Jayaram, SQ Wong, ... Nature communications 14 (1), 4823, 2023 | 4 | 2023 |
Immunosuppression in the prostate tumor microenvironment is tied to androgen deprivation therapy-resistant club-like cells A Kiviaho, SK Eerola, HML Kallio, MK Andersen, X Spotbeen, A Giesen, ... bioRxiv, 2024.03. 25.586330, 2024 | 1 | 2024 |
Androgen deprivation therapy-resistant club cells are linked to myeloid cell-driven immunosuppression in the prostate tumor microenvironment A Kiviaho, SK Eerola, HM Kallio, MK Andersen, X Spotbeen, A Giesen, ... | 1 | 2024 |
Publisher correction: spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer K Joshi, MR de Massy, M Ismail, JL Reading, I Uddin, A Woolston, ... Nature Medicine 26 (7), 1148-1148, 2020 | 1 | 2020 |
Characterisation of the TCR repertoire in NSCLC to reveal the relationship between TCR heterogeneity and genetic heterogeneity that is influenced by mutational load and is … K Joshi, M Ismail, JL Reading, M Robert De Massy, I Uddin, ... Journal of Clinical Oncology 36 (15_suppl), 12009-12009, 2018 | 1 | 2018 |
Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer SP Pitzen, AN Rudenick, Y Qiu, W Zhang, SA Munro, BM McCluskey, ... Proceedings of the National Academy of Sciences 122 (6), e2415308122, 2025 | | 2025 |
Molecular effects of neo-adjuvant hormone therapy for locally advanced prostate cancer: An ancillary study of the ARNEO phase 2 trial M Ismail, W Devlies, M Parry, G Devos, S Friedrich, C Parker, L Mendes, ... Cancer Research 84 (6_Supplement), 7568-7568, 2024 | | 2024 |
Treatment-mediated selection of lethal prostate cancer clones defined by copy number architectures AMM Hasan, P Cremaschi, D Wetterskog, A Jayaram, SQ Wong, ... bioRxiv, 2022.09. 01.506183, 2022 | | 2022 |