Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death CR Bezzina, J Barc, Y Mizusawa, CA Remme, JB Gourraud, F Simonet, ... Nature genetics 45 (9), 1044-1049, 2013 | 577 | 2013 |
Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system ML Bakker, BJ Boukens, MTM Mommersteeg, JF Brons, V Wakker, ... Circulation research 102 (11), 1340-1349, 2008 | 249 | 2008 |
Identification and functional characterization of cardiac pacemaker cells in zebrafish F Tessadori, JH van Weerd, SB Burkhard, AO Verkerk, E de Pater, ... Public Library of Science 7 (10), e47644, 2012 | 222 | 2012 |
T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells ML Bakker, GJJ Boink, BJ Boukens, AO Verkerk, M van den Boogaard, ... Cardiovascular research 94 (3), 439-449, 2012 | 189 | 2012 |
Misinterpretation of the mouse ECG: ‘musing the waves of Mus musculus’ BJ Boukens, MR Rivaud, S Rentschler, R Coronel The Journal of physiology 592 (21), 4613-4626, 2014 | 176 | 2014 |
Developmental basis for electrophysiological heterogeneity in the ventricular and outflow tract myocardium as a substrate for life-threatening ventricular arrhythmias BJD Boukens, VM Christoffels, R Coronel, AFM Moorman Circulation research 104 (1), 19-31, 2009 | 168 | 2009 |
Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm RD Nadadur, MT Broman, B Boukens, SR Mazurek, X Yang, ... Science translational medicine 8 (354), 354ra115-354ra115, 2016 | 167 | 2016 |
Identifying the evolutionary building blocks of the cardiac conduction system B Jensen, BJD Boukens, AV Postma, QD Gunst, MJB van den Hoff, ... Public Library of Science 7 (9), e44231, 2012 | 127 | 2012 |
Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice WTJ Aanhaanen, BJD Boukens, A Sizarov, V Wakker, C de Gier-de Vries, ... The Journal of clinical investigation 121 (2), 534-544, 2011 | 110 | 2011 |
Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility J Barc, R Tadros, C Glinge, DY Chiang, M Jouni, F Simonet, SJ Jurgens, ... Nature genetics 54 (3), 232-239, 2022 | 104 | 2022 |
Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties BS Gillers, A Chiplunkar, H Aly, T Valenta, K Basler, VM Christoffels, ... Circulation research 116 (3), 398-406, 2015 | 100 | 2015 |
Identification of atrial fibrillation associated genes and functional non-coding variants AF van Ouwerkerk, FM Bosada, K van Duijvenboden, MC Hill, ... Nature communications 10 (1), 4755, 2019 | 90 | 2019 |
ElectroMap: high-throughput open-source software for analysis and mapping of cardiac electrophysiology C O’Shea, AP Holmes, TY Yu, J Winter, SP Wells, J Correia, BJ Boukens, ... Scientific reports 9 (1), 1389, 2019 | 90 | 2019 |
Reduced sodium channel function unmasks residual embryonic slow conduction in the adult right ventricular outflow tract BJ Boukens, M Sylva, C de Gier-de Vries, CA Remme, CR Bezzina, ... Circulation Research 113 (2), 137-141, 2013 | 90 | 2013 |
Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program VWW Van Eif, S Stefanovic, K Van Duijvenboden, M Bakker, V Wakker, ... Development 146 (8), dev173161, 2019 | 84 | 2019 |
Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to-batch variations S Hamad, D Derichsweiler, S Papadopoulos, F Nguemo, T Šarić, ... Theranostics 9 (24), 7222, 2019 | 78 | 2019 |
The Brugada Syndrome Susceptibility Gene HEY2 Modulates Cardiac Transmural Ion Channel Patterning and Electrical Heterogeneity CC Veerman, S Podliesna, R Tadros, EM Lodder, I Mengarelli, ... Circulation research 121 (5), 537-548, 2017 | 76 | 2017 |
Early repolarization in mice causes overestimation of ventricular activation time by the QRS duration BJ Boukens, MG Hoogendijk, AO Verkerk, A Linnenbank, P van Dam, ... Cardiovascular research 97 (1), 182-191, 2013 | 70 | 2013 |
Dietary fish oil reduces pacemaker current and heart rate in rabbit AO Verkerk, HM den Ruijter, J Bourier, BJ Boukens, IA Brouwer, ... Heart Rhythm 6 (10), 1485-1492, 2009 | 67 | 2009 |
Transmural APD gradient synchronizes repolarization in the human left ventricular wall BJ Boukens, MS Sulkin, CR Gloschat, FS Ng, EJ Vigmond, IR Efimov Cardiovascular research 108 (1), 188-196, 2015 | 63 | 2015 |