Lost in Transition: Startup of Glycolysis Yields Subpopulations of Nongrowing Cells JH van Heerden, MT Wortel, FJ Bruggeman, JJ Heijnen, YJM Bollen, ... Science, 1245114, 2014 | 329 | 2014 |
Taking chances and making mistakes: non-genetic phenotypic heterogeneity and its consequences for surviving in dynamic environments C van Boxtel, JH van Heerden, N Nordholt, P Schmidt, FJ Bruggeman Journal of The Royal Society Interface 14 (132), 20170141, 2017 | 111 | 2017 |
Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies IE Elsemman, A Rodriguez Prado, P Grigaitis, M Garcia Albornoz, ... Nature communications 13 (1), 1-12, 2022 | 88 | 2022 |
Statistics and simulation of growth of single bacterial cells: illustrations with B. subtilis and E. coli JH Heerden, H Kempe, A Doerr, T Maarleveld, N Nordholt, FJ Bruggeman Scientific reports 7 (16094), 2017 | 56 | 2017 |
Biphasic cell-size and growth-rate homeostasis by single Bacillus subtilis cells N Nordholt, JH van Heerden, FJ Bruggeman Current Biology 30 (12), 2238-2247. e5, 2020 | 53 | 2020 |
Parallel changes in gene expression in peripheral blood mononuclear cells and the brain after maternal separation in the mouse JH van Heerden, A Conesa, DJ Stein, D Montaner, V Russell, N Illing BMC research notes 2 (1), 1-10, 2009 | 52 | 2009 |
Effects of growth rate and promoter activity on single-cell protein expression N Nordholt, J van Heerden, R Kort, FJ Bruggeman Scientific Reports 7 (6299), 2017 | 50 | 2017 |
Multi‐tasking of biosynthetic and energetic functions of glycolysis explained by supply and demand logic JH van Heerden, FJ Bruggeman, B Teusink BioEssays 37 (1), 34-45, 2015 | 44 | 2015 |
An improved ATP FRET sensor for yeast shows heterogeneity during nutrient transitions D Botman, JH van Heerden, B Teusink ACS sensors 5 (3), 814-822, 2020 | 37 | 2020 |
Evaluating the behavioural consequences of early maternal separation in adult C57BL/6 mice; the importance of time JH van Heerden, V Russell, A Korff, DJ Stein, N Illing Behavioural brain research 207 (2), 332-342, 2010 | 37 | 2010 |
Structural and biochemical characterization of a nitrilase from the thermophilic bacterium, Geobacillus pallidus RAPc8 DS Williamson, KC Dent, BW Weber, A Varsani, J Frederick, RN Thuku, ... Applied microbiology and biotechnology 88 (1), 143-153, 2010 | 32 | 2010 |
A yeast FRET biosensor enlightens cAMP signaling D Botman, TG O’Toole, J Goedhart, FJ Bruggeman, JH van Heerden, ... Molecular Biology of the Cell 32 (13), 1229-1240, 2021 | 23 | 2021 |
Metabolism at Evolutionary Optimal States I Rabbers, JH van Heerden, N Nordholt, H Bachmann, B Teusink, ... Metabolites 5 (2), 311-343, 2015 | 19 | 2015 |
pH dependencies of glycolytic enzymes of yeast under in vivo‐like assay conditions L Luzia, D Lao‐Martil, P Savakis, J van Heerden, N van Riel, B Teusink The FEBS Journal, 2022 | 11 | 2022 |
Serial propagation in water-in-oil emulsions selects for Saccharomyces cerevisiae strains with a reduced cell size or an increased biomass yield on glucose RJ van Tatenhove-Pel, E Zwering, DF Boreel, M Falk, JH van Heerden, ... Metabolic Engineering 64, 1-14, 2021 | 11 | 2021 |
Fatal attraction in glycolysis: how Saccharomyces cerevisiae manages sudden transitions to high glucose JH van Heerden, MT Wortel, FJ Bruggeman, JJ Heijnen, Y JM Microbial Cell 1 (3), 103-106, 2014 | 11 | 2014 |
A computational toolbox to investigate the metabolic potential and resource allocation in fission yeast P Grigaitis, DAJ Grundel, E van Pelt-KleinJan, M Isaku, G Xie, SM Farias, ... mSystems, 2022 | 7 | 2022 |
Growth consequences of the inhomogeneous organization of the bacterial cytoplasm JH van Heerden, AM Berkvens, DH de Groot, FJ Bruggeman bioRxiv, 2023.04. 18.537336, 2023 | 5 | 2023 |
A framework for the informed normalization of printed microarrays J Van Heerden, SA Walford, A Shen, N Illing South African Journal of Science 103 (9), 381-390, 2007 | 2 | 2007 |
Integrated biphasic growth rate, gene expression, and cell-size homeostasis behaviour of single B. subtilis cells N Nordholt, JH van Heerden, FJ Bruggeman bioRxiv, 510925, 2019 | 1 | 2019 |