A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment V López Del Amo, AL Bishop, HM Sánchez C, JB Bennett, X Feng, ... Nature communications 11 (1), 1-12, 2020 | 74 | 2020 |
Mitochondrial defects and neuromuscular degeneration caused by altered expression of Drosophila Gdap1: implications for the Charcot–Marie–Tooth neuropathy V López Del Amo, M Seco-Cervera, JL García-Giménez, AJ Whitworth, ... Human molecular genetics 24 (1), 21-36, 2015 | 57 | 2015 |
Small-molecule control of super-Mendelian inheritance in gene drives VL Del Amo, BS Leger, KJ Cox, S Gill, AL Bishop, GD Scanlon, JA Walker, ... Cell reports 31 (13), 107841, 2020 | 54 | 2020 |
Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes X Feng, V López Del Amo, E Mameli, M Lee, AL Bishop, N Perrimon, ... Nature communications 12 (1), 1-13, 2021 | 48 | 2021 |
Redox modifications of proteins of the mitochondrial fusion and fission machinery C Wolf, V López del Amo, S Arndt, D Bueno, S Tenzer, EM Hanschmann, ... Cells 9 (4), 815, 2020 | 37 | 2020 |
A Drosophila model of GDAP1 function reveals the involvement of insulin signalling in the mitochondria-dependent neuromuscular degeneration VL Del Amo, M Palomino-Schätzlein, M Seco-Cervera, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (3), 801-809, 2017 | 26 | 2017 |
The Drosophila junctophilin gene is functionally equivalent to its four mammalian counterparts and is a modifier of a Huntingtin poly-Q expansion and the Notch … E Calpena, V Lopez del Amo, M Chakraborty, B Llamusí, R Artero, ... Disease models & mechanisms 11 (1), dmm029082, 2018 | 22 | 2018 |
Cas9/Nickase-induced allelic conversion by homologous chromosome-templated repair in Drosophila somatic cells S Roy, SS Juste, M Sneider, A Auradkar, C Klanseck, Z Li, AHF Julio, ... Science Advances 8 (26), eabo0721, 2022 | 18 | 2022 |
Next-generation CRISPR gene-drive systems using Cas12a nuclease S Sanz Juste, EM Okamoto, C Nguyen, X Feng, V López Del Amo Nature Communications 14 (1), 6388, 2023 | 15 | 2023 |
A nickase Cas9 gene-drive system promotes super-Mendelian inheritance in Drosophila VL Del Amo, SS Juste, VM Gantz Cell Reports 39 (8), 110843, 2022 | 12 | 2022 |
Double-tap gene drive uses iterative genome targeting to help overcome resistance alleles AL Bishop, V López Del Amo, EM Okamoto, Z Bodai, AC Komor, ... Nature communications 13 (1), 1-11, 2022 | 12 | 2022 |
Mild Muscle Mitochondrial Fusion Distress Extends Drosophila Lifespan through an Early and Systemic Metabolome Reorganization A Tapia, M Palomino-Schätzlein, M Roca, A Lahoz, A Pineda-Lucena, ... International journal of molecular sciences 22 (22), 12133, 2021 | 2 | 2021 |
CRISPR-Cas9 and Cas12a target site richness reflects genomic diversity in natural populations of Anopheles gambiae and Aedes aegypti mosquitoes TC Collier, Y Lee, DK Mathias, VL Del Amo BMC genomics 25 (1), 1-9, 2024 | | 2024 |
Expanding the CRISPR base editing toolbox in Drosophila melanogaster M Clark, C Nguyen, H Nguyen, A Tay, SJ Beach, M Maselko, ... Communications Biology 7 (1), 1126, 2024 | | 2024 |