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Aartjan (AJ) te Velthuis
Aartjan (AJ) te Velthuis
Assistant Professor, Princeton University
Adresă de e-mail confirmată pe princeton.edu - Pagina de pornire
Titlu
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Zn2+ inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture
AJW Te Velthuis, SHE van den Worm, AC Sims, RS Baric, EJ Snijder, ...
PLoS pathogens 6 (11), e1001176, 2010
11772010
Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis
AJW Te Velthuis, E Fodor
Nature Reviews Microbiology 14 (8), 479-493, 2016
5102016
The mechanism of resistance to favipiravir in influenza
DH Goldhill, AJW Te Velthuis, RA Fletcher, P Langat, M Zambon, ...
Proceedings of the National Academy of Sciences 115 (45), 11613-11618, 2018
3382018
The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension
AJW Te Velthuis, SHE Van Den Worm, EJ Snijder
Nucleic acids research 40 (4), 1737-1747, 2012
3312012
The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent
AJW Te Velthuis, JJ Arnold, CE Cameron, SHE Van Den Worm, ...
Nucleic acids research 38 (1), 203-214, 2010
2842010
Common and unique features of viral RNA-dependent polymerases
AJW Te Velthuis
Cellular and molecular life sciences 71, 4403-4420, 2014
2582014
Mechanism of nucleic acid unwinding by SARS-CoV helicase
AO Adedeji, B Marchand, AJW Te Velthuis, EJ Snijder, S Weiss, RL Eoff, ...
PloS one 7 (5), e36521, 2012
2222012
Single-cell virus sequencing of influenza infections that trigger innate immunity
AB Russell, E Elshina, JR Kowalsky, AJW Te Velthuis, JD Bloom
Journal of virology 93 (14), 10.1128/jvi. 00500-19, 2019
1312019
Quantitative guidelines for force calibration through spectral analysis of magnetic tweezers data
AJW Te Velthuis, JWJ Kerssemakers, J Lipfert, NH Dekker
Biophysical journal 99 (4), 1292-1302, 2010
1312010
Nidovirus RNA polymerases: complex enzymes handling exceptional RNA genomes
CC Posthuma, AJW te Velthuis, EJ Snijder
Virus Research, 2017
1302017
Structure and function of the influenza virus transcription and replication machinery
E Fodor, AJW Te Velthuis
Cold Spring Harbor perspectives in medicine 10 (9), a038398, 2020
1262020
Mini viral RNAs act as innate immune agonists during influenza virus infection
AJW Te Velthuis, JC Long, DLV Bauer, RLY Fan, HL Yen, J Sharps, ...
Nature microbiology 3 (11), 1234-1242, 2018
1262018
The role of the priming loop in influenza A virus RNA synthesis
AJW Te Velthuis, NC Robb, AN Kapanidis, E Fodor
Nature microbiology 1 (5), 1-7, 2016
1222016
Structural insights into RNA polymerases of negative-sense RNA viruses
AJW Te Velthuis, JM Grimes, E Fodor
Nature Reviews Microbiology 19 (5), 303-318, 2021
1182021
PDZ and LIM domain‐encoding genes: molecular interactions and their role in development
AJW Te Velthuis, CP Bagowski
The Scientific World Journal 7 (1), 1470-1492, 2007
1122007
Molecular evolution of the MAGUK family in metazoan genomes
AJW Te Velthuis, JF Admiraal, CP Bagowski
BMC evolutionary biology 7, 1-10, 2007
902007
Insights into the molecular evolution of the PDZ/LIM family and identification of a novel conserved protein motif
AJW Te Velthuis, T Isogai, L Gerrits, CP Bagowski
PloS one 2 (2), e189, 2007
882007
Integrity of the early secretory pathway promotes, but is not required for, severe acute respiratory syndrome coronavirus RNA synthesis and virus-induced remodeling of …
K Knoops, C Swett-Tapia, SHE Van Den Worm, AJW Te Velthuis, ...
Journal of virology 84 (2), 833-846, 2010
772010
Role of the PB2 627 domain in influenza A virus polymerase function
BE Nilsson, AJW Te Velthuis, E Fodor
Journal of virology 91 (7), 10.1128/jvi. 02467-16, 2017
692017
OTUB1 is a key regulator of RIG-I-dependent immune signaling and is targeted for proteasomal degradation by influenza A NS1
AS Jahan, E Biquand, R Munoz-Moreno, A Le Quang, CKP Mok, ...
Cell reports 30 (5), 1570-1584. e6, 2020
622020
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