Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19 JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ... Immunity 53 (6), 1296-1314. e9, 2020 | 341 | 2020 |
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms M Ostaszewski, A Niarakis, A Mazein, I Kuperstein, R Phair, ... Molecular systems biology 17 (10), e10387, 2021 | 100 | 2021 |
FBA reveals guanylate kinase as a potential target for antiviral therapies against SARS-CoV-2 A Renz, L Widerspick, A Draeger Bioinformatics 36 (Supplement_2), i813-i821, 2020 | 51 | 2020 |
Genome-scale metabolic model of infection with SARS-CoV-2 mutants confirms guanylate kinase as robust potential antiviral target A Renz, L Widerspick, A Dräger Genes 12 (6), 796, 2021 | 37 | 2021 |
High-Quality Genome-Scale Reconstruction of Corynebacterium glutamicum ATCC 13032 M Feierabend, A Renz, E Zelle, K Nöh, W Wiechert, A Dräger Frontiers in microbiology 12, 750206, 2021 | 25 | 2021 |
An updated genome-scale metabolic network reconstruction of Pseudomonas aeruginosa PA14 to characterize mucin-driven shifts in bacterial metabolism D Payne, A Renz, LJ Dunphy, T Lewis, A Dräger, JA Papin npj Systems Biology and Applications 7 (1), 1-8, 2021 | 15 | 2021 |
Clinical applications of metabolic models in SBML format A Renz, R Mostolizadeh, A Dräger Elsevier, 2020 | 15 | 2020 |
Curating and comparing 114 strain-specific genome-scale metabolic models of Staphylococcus aureus A Renz, A Dräger npj Systems Biology and Applications 7 (1), 1-15, 2021 | 13 | 2021 |
First genome-scale metabolic model of Dolosigranulum pigrum confirms multiple auxotrophies A Renz, L Widerspick, A Dräger Metabolites 11 (4), 232, 2021 | 12 | 2021 |
SBOannotator: a Python tool for the automated assignment of systems biology ontology terms N Leonidou, E Fritze, A Renz, A Dräger Bioinformatics 39 (7), btad437, 2023 | 11 | 2023 |
HCA Lung Biological Network; Deutsche COVID-19 Omics Initiative (DeCOI), Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and … JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ... Immunity 53 (1296-1314), e9, 2020 | 11 | 2020 |
Genome-scale model of Pseudomonas aeruginosa metabolism unveils virulence and drug potentiation S Dahal, A Renz, A Dräger, L Yang Communications biology 6 (1), 165, 2023 | 8 | 2023 |
Systems medicine A Renz, R Mostolizadeh, A Dräger Academic Press 3, 362-371, 2020 | 8 | 2020 |
Metabolic modeling elucidates phenformin and atpenin A5 as broad-spectrum antiviral drugs A Renz, M Hohner, M Breitenbach, J Josephs-Spaulding, J Dürrwald, ... | 6 | 2022 |
New workflow predicts drug targets against SARS-CoV-2 via metabolic changes in infected cells N Leonidou, A Renz, R Mostolizadeh, A Dräger PLOS Computational Biology 19 (3), e1010903, 2023 | 5 | 2023 |
Network HCALB, Deutsche COI. Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19 JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ... Immunity 53 (6), 1296-1314, 2020 | 5 | 2020 |
Frog analysis ensures the reproducibility of genome scale metabolic models K Raman, M Kratochvil, BG Olivier, M König, P Sengupta, ... bioRxiv, 2024.09. 24.614797, 2024 | 3 | 2024 |
Genome-scale modeling of Pseudomonas aeruginosa PA14 unveils its broad metabolic capabilities and role of metabolism in drug potentiation S Dahal, A Renz, A Dräger, L Yang BioRxiv, 2021.04. 15.439930, 2021 | 3 | 2021 |
Metabolic Modeling Elucidates Phenformin and Atpenin A5 as Broad-Spectrum Antiviral Drugs A Dräger, C Kaleta, M Schindler, F Cabreiro, G Marinos, R Jami, L Best, ... Preprints. org, 2024 | | 2024 |
Genome-scale metabolic model of Staphylococcus epidermidis ATCC 12228 matches in vitro conditions N Leonidou, A Renz, B Winnerling, A Grekova, F Grein, A Dräger bioRxiv, 2023.12. 19.572329, 2023 | | 2023 |