| A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment S Vanni, H Hirose, H Barelli, B Antonny, R Gautier Nature communications 5 (1), 4916, 2014 | 280 | 2014 |
| Transient focal membrane deformation induced by arginine-rich peptides leads to their direct penetration into cells H Hirose, T Takeuchi, H Osakada, S Pujals, S Katayama, I Nakase, ... Molecular Therapy 20 (5), 984-993, 2012 | 277 | 2012 |
| Elucidating cell-penetrating peptide mechanisms of action for membrane interaction, cellular uptake, and translocation utilizing the hydrophobic counter-anion pyrenebutyrate P Guterstam, F Madani, H Hirose, T Takeuchi, S Futaki, SEL Andaloussi, ... Biochimica et biophysica acta (BBA)-biomembranes 1788 (12), 2509-2517, 2009 | 173 | 2009 |
| Cell-surface accumulation of flock house virus-derived peptide leads to efficient internalization via macropinocytosis I Nakase, H Hirose, G Tanaka, A Tadokoro, S Kobayashi, T Takeuchi, ... Molecular Therapy 17 (11), 1868-1876, 2009 | 137 | 2009 |
| Effect of the attachment of a penetration accelerating sequence and the influence of hydrophobicity on octaarginine-mediated intracellular delivery K Takayama, H Hirose, G Tanaka, S Pujals, S Katayama, I Nakase, ... Molecular pharmaceutics 9 (5), 1222-1230, 2012 | 102 | 2012 |
| Dynamic amphiphile libraries to screen for the “fragrant” delivery of siRNA into HeLa cells and human primary fibroblasts C Gehin, J Montenegro, EK Bang, A Cajaraville, S Takayama, H Hirose, ... Journal of the American Chemical Society 135 (25), 9295-9298, 2013 | 99 | 2013 |
| Acylation of octaarginine: Implication to the use of intracellular delivery vectors S Katayama, H Hirose, K Takayama, I Nakase, S Futaki Journal of controlled release 149 (1), 29-35, 2011 | 93 | 2011 |
| Arginine-rich peptides: methods of translocation through biological membranes S Futaki, H Hirose, I Nakase Current pharmaceutical design 19 (16), 2863-2868, 2013 | 86 | 2013 |
| Curvature engineering: Positive membrane curvature induced by epsin N-terminal peptide boosts internalization of octaarginine S Pujals, H Miyamae, S Afonin, T Murayama, H Hirose, I Nakase, ... ACS Chemical Biology 8 (9), 1894-1899, 2013 | 73 | 2013 |
| Transformation of an antimicrobial peptide into a plasma membrane-permeable, mitochondria-targeted peptide via the substitution of lysine with arginine I Nakase, S Okumura, S Katayama, H Hirose, S Pujals, H Yamaguchi, ... Chemical Communications 48 (90), 11097-11099, 2012 | 60 | 2012 |
| Modeling the endosomal escape of cell-penetrating peptides using a transmembrane pH gradient F Madani, R Abdo, S Lindberg, H Hirose, S Futaki, Ü Langel, A Gräslund Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (4), 1198-1204, 2013 | 59 | 2013 |
| Stimulating macropinocytosis for intracellular nucleic acid and protein delivery: A combined strategy with membrane-lytic peptides to facilitate endosomal escape JVV Arafiles, H Hirose, M Akishiba, S Tsuji, M Imanishi, S Futaki Bioconjugate Chemistry 31 (3), 547-553, 2020 | 49 | 2020 |
| Liquid droplet formation and facile cytosolic translocation of IgG in the presence of attenuated cationic amphiphilic lytic peptides T Iwata, H Hirose, K Sakamoto, Y Hirai, JVV Arafiles, M Akishiba, ... Angewandte Chemie International Edition 60 (36), 19804-19812, 2021 | 46 | 2021 |
| Effect of surface modifications on cellular uptake of gold nanorods in human primary cells and established cell lines Y Xiao, W Xu, Y Komohara, Y Fujiwara, H Hirose, S Futaki, T Niidome ACS omega 5 (50), 32744-32752, 2020 | 31 | 2020 |
| Peptide-assisted intracellular delivery of biomacromolecules S Futaki, JVV Arafiles, H Hirose Chemistry Letters 49 (9), 1088-1094, 2020 | 31 | 2020 |
| Oligoarginine-bearing tandem repeat penetration-accelerating sequence delivers protein to cytosol via caveolae-mediated endocytosis A Okuda, S Tahara, H Hirose, T Takeuchi, I Nakase, A Ono, M Takehashi, ... Biomacromolecules 20 (5), 1849-1859, 2019 | 30 | 2019 |
| Expressed protein ligation for the preparation of fusion proteins with cell penetrating peptides for endotoxin removal and intracellular delivery HH Yu, I Nakase, S Pujals, H Hirose, G Tanaka, S Katayama, M Imanishi, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1798 (12), 2249-2257, 2010 | 26 | 2010 |
| In vitro expression of genetically encoded non-standard peptides consisting of exotic amino acid building blocks H Hirose, C Tsiamantas, T Katoh, H Suga Current opinion in biotechnology 58, 28-36, 2019 | 22 | 2019 |
| Cytosolic protein delivery using pH-responsive, charge-reversible lipid nanoparticles Y Hirai, H Hirose, M Imanishi, T Asai, S Futaki Scientific reports 11 (1), 19896, 2021 | 21 | 2021 |
| Discovery of a Macropinocytosis‐Inducing Peptide Potentiated by Medium‐Mediated Intramolecular Disulfide Formation JVV Arafiles, H Hirose, Y Hirai, M Kuriyama, MM Sakyiamah, W Nomura, ... Angewandte Chemie 133 (21), 12035-12043, 2021 | 18 | 2021 |
Jan Vincent V. ArafilesLeibniz Forschungsinstitut für Molekulare PharmakologieAdresă de e-mail confirmată pe fmp-berlin.de
