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Alexis Komor
Alexis Komor
Associate Professor, UCSD
Adresă de e-mail confirmată pe ucsd.edu - Pagina de pornire
Titlu
Citat de
Citat de
Anul
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
AC Komor, YB Kim, MS Packer, JA Zuris, DR Liu
Nature 533 (7603), 420-424, 2016
54952016
Programmable base editing of A• T to G• C in genomic DNA without DNA cleavage
NM Gaudelli, AC Komor, HA Rees, MS Packer, AH Badran, DI Bryson, ...
Nature 551 (7681), 464-471, 2017
41172017
CRISPR-based technologies for the manipulation of eukaryotic genomes
AC Komor, AH Badran, DR Liu
Cell 168 (1), 20-36, 2017
13232017
Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions
YB Kim, AC Komor, JM Levy, MS Packer, KT Zhao, DR Liu
Nature biotechnology 35 (4), 371-376, 2017
9052017
Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C: G-to-T: A base editors with higher efficiency and product purity
AC Komor, KT Zhao, MS Packer, NM Gaudelli, AL Waterbury, LW Koblan, ...
Science advances 3 (8), eaao4774, 2017
8772017
Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery
HA Rees, AC Komor, WH Yeh, J Caetano-Lopes, M Warman, ASB Edge, ...
Nature communications 8 (1), 15790, 2017
5082017
Global chemical effects of the microbiome include new bile-acid conjugations
RA Quinn, AV Melnik, A Vrbanac, T Fu, KA Patras, MP Christy, Z Bodai, ...
Nature 579 (7797), 123-129, 2020
4802020
The path for metal complexes to a DNA target
AC Komor, JK Barton
Chemical Communications 49 (35), 3617-3630, 2013
4162013
Base editing: advances and therapeutic opportunities
EM Porto, AC Komor, IM Slaymaker, GW Yeo
Nature Reviews Drug Discovery 19 (12), 839-859, 2020
3852020
Fusions of Cas9 domains and nucleic acid-editing domains
DR Liu, AC Komor
US Patent 11,053,481, 2021
1582021
Editing the genome without double-stranded DNA breaks
AC Komor, AH Badran, DR Liu
ACS chemical biology 13 (2), 383-388, 2018
1302018
Methods for nucleic acid editing
DR Liu, AC Komor
US Patent 9,840,699, 2017
1022017
Methods for correcting caspase-9 point mutations
DR Liu, AC Komor
US Patent App. 14/326,303, 2015
1022015
Methods for correcting presenilin point mutations
DR Liu, AC Komor
US Patent 9,068,179, 2015
972015
Methods for correcting alpha-antitrypsin point mutations
DR Liu, AC Komor
US Patent App. 14/326,290, 2015
952015
Methods for correcting pi3k point mutations
DR Liu, AC Komor
US Patent App. 14/326,140, 2015
932015
Nucleobase editors and uses thereof
DR Liu, AC Komor, HA Rees, Y Kim
US Patent 10,167,457, 2019
912019
Methods for correcting von willebrand factor point mutations
DR Liu, AC Komor
US Patent App. 14/326,318, 2015
912015
Cell-selective biological activity of rhodium metalloinsertors correlates with subcellular localization
AC Komor, CJ Schneider, AG Weidmann, JK Barton
Journal of the American Chemical Society 134 (46), 19223-19233, 2012
902012
Cas variants for gene editing
DR Liu, AC Komor
US Patent 10,465,176, 2019
732019
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