| Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach SA Carr, SE Abbatiello, BL Ackermann, C Borchers, B Domon, ... Molecular & Cellular Proteomics 13 (3), 907-917, 2014 | 581 | 2014 |
| Mitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway X Guo, G Aviles, Y Liu, R Tian, BA Unger, YHT Lin, AP Wiita, K Xu, ... Nature 579 (7799), 427-432, 2020 | 514 | 2020 |
| Force-dependent chemical kinetics of disulfide bond reduction observed with single-molecule techniques AP Wiita, SRK Ainavarapu, HH Huang, JM Fernandez Proceedings of the National Academy of Sciences 103 (19), 7222-7227, 2006 | 429 | 2006 |
| The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles AM Leidal, HH Huang, T Marsh, T Solvik, D Zhang, J Ye, FB Kai, ... Nature cell biology 22 (2), 187-199, 2020 | 410 | 2020 |
| Contour length and refolding rate of a small protein controlled by engineered disulfide bonds SRK Ainavarapu, J Brujić, HH Huang, AP Wiita, H Lu, L Li, KA Walther, ... Biophysical journal 92 (1), 225-233, 2007 | 380 | 2007 |
| Probing the chemistry of thioredoxin catalysis with force AP Wiita, R Perez-Jimenez, KA Walther, F Gräter, BJ Berne, A Holmgren, ... Nature 450 (7166), 124-127, 2007 | 332 | 2007 |
| Engineered ACE2 receptor traps potently neutralize SARS-CoV-2 A Glasgow, J Glasgow, D Limonta, P Solomon, I Lui, Y Zhang, MA Nix, ... Proceedings of the National Academy of Sciences 117 (45), 28046-28055, 2020 | 258 | 2020 |
| Single-molecule force spectroscopy measurements of bond elongation during a bimolecular reaction SR Koti Ainavarapu, AP Wiita, L Dougan, E Uggerud, JM Fernandez Journal of the American Chemical Society 130 (20), 6479-6487, 2008 | 166 | 2008 |
| Molecular targeting of inhibitor of apoptosis proteins based on small molecule mimics of natural binding partners RA Kipp, MA Case, AD Wist, CM Cresson, M Carrell, E Griner, A Wiita, ... Biochemistry 41 (23), 7344-7349, 2002 | 151 | 2002 |
| Cellular phenotypes in human iPSC-derived neurons from a genetic model of autism spectrum disorder A Deshpande, S Yadav, DQ Dao, ZY Wu, KC Hokanson, MK Cahill, ... Cell reports 21 (10), 2678-2687, 2017 | 141 | 2017 |
| Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles O Julien, M Zhuang, AP Wiita, AJ O’Donoghue, GM Knudsen, CS Craik, ... Proceedings of the National Academy of Sciences 113 (14), E2001-E2010, 2016 | 126 | 2016 |
| The p97 inhibitor CB-5083 is a unique disrupter of protein homeostasis in models of multiple myeloma R Le Moigne, BT Aftab, S Djakovic, E Dhimolea, E Valle, M Murnane, ... Molecular cancer therapeutics 16 (11), 2375-2386, 2017 | 117 | 2017 |
| Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy R Perez-Jimenez, J Li, P Kosuri, I Sanchez-Romero, AP Wiita, ... Nature structural & molecular biology 16 (8), 890-896, 2009 | 116 | 2009 |
| Phosphorylation of β-tubulin by the Down syndrome kinase, minibrain/DYRK1a, regulates microtubule dynamics and dendrite morphogenesis KM Ori-McKenney, RJ McKenney, HH Huang, T Li, S Meltzer, LY Jan, ... Neuron 90 (3), 551-563, 2016 | 110 | 2016 |
| Secretory autophagy maintains proteostasis upon lysosome inhibition TA Solvik, TA Nguyen, YH Tony Lin, T Marsh, EJ Huang, AP Wiita, ... Journal of Cell Biology 221 (6), 2022 | 105 | 2022 |
| Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells DW Sherbenou, BT Aftab, Y Su, CR Behrens, A Wiita, AC Logan, ... The Journal of clinical investigation 126 (12), 4640-4653, 2016 | 102 | 2016 |
| Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies ND Trinklein, D Pham, U Schellenberger, B Buelow, A Boudreau, ... MAbs 11 (4), 639-652, 2019 | 92 | 2019 |
| IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells J Lee, ME Robinson, N Ma, D Artadji, MA Ahmed, G Xiao, T Sadras, ... Nature 588 (7838), 491-497, 2020 | 88 | 2020 |
| Global cellular response to chemotherapy-induced apoptosis AP Wiita, E Ziv, PJ Wiita, A Urisman, O Julien, AL Burlingame, ... Elife 2, e01236, 2013 | 83 | 2013 |
| Time-resolved proteomics extends ribosome profiling-based measurements of protein synthesis dynamics TY Liu, HH Huang, D Wheeler, Y Xu, JA Wells, YS Song, AP Wiita Cell systems 4 (6), 636-644. e9, 2017 | 80 | 2017 |
