| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 11057 | 2021 |
| Glucagon-like peptide 1 protects pancreatic β-cells from death by increasing autophagic flux and restoring lysosomal function FP Zummo, KS Cullen, M Honkanen-Scott, JAM Shaw, PE Lovat, C Arden Diabetes 66 (5), 1272-1285, 2017 | 138 | 2017 |
| Fructose 2, 6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes C Arden, SJ Tudhope, JL Petrie, ZH Al-Oanzi, KS Cullen, AJ Lange, ... Biochemical Journal 443 (1), 111-123, 2012 | 137 | 2012 |
| Elevated glucose represses liver glucokinase and induces its regulatory protein to safeguard hepatic phosphate homeostasis C Arden, JL Petrie, SJ Tudhope, Z Al-Oanzi, AJ Claydon, RJ Beynon, ... Diabetes 60 (12), 3110-3120, 2011 | 83 | 2011 |
| Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of glucokinase in hepatocytes VA Payne, C Arden, C Wu, AJ Lange, L Agius Diabetes 54 (7), 1949-1957, 2005 | 75 | 2005 |
| Glucokinase is an integral component of the insulin granules in glucose-responsive insulin secretory cells and does not translocate during glucose stimulation C Arden, A Harbottle, S Baltrusch, M Tiedge, L Agius Diabetes 53 (9), 2346-2352, 2004 | 62 | 2004 |
| A novel mechanism for regulating hepatic glycogen synthesis involving serotonin and cyclin-dependent kinase-5 SJ Tudhope, CC Wang, JL Petrie, L Potts, F Malcomson, J Kieswich, ... Diabetes 61 (1), 49-60, 2012 | 56 | 2012 |
| A role for PFK-2/FBPase-2, as distinct from fructose 2, 6-bisphosphate, in regulation of insulin secretion in pancreatic β-cells C Arden, LJ Hampson, GC Huang, JAM Shaw, A Aldibbiat, G Holliman, ... Biochemical Journal 411 (1), 41-51, 2008 | 55 | 2008 |
| Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase MH Mukhtar, VA Payne, C Arden, A Harbottle, S Khan, AJ Lange, L Agius American Journal of Physiology-Regulatory, Integrative and Comparative …, 2008 | 50 | 2008 |
| Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site LJ Hampson, C Arden, L Agius, M Ganotidis, MN Kosmopoulou, C Tiraidis, ... Bioorganic & medicinal chemistry 14 (23), 7835-7845, 2006 | 47 | 2006 |
| The role of protein kinase B/Akt in insulin-induced inactivation of phosphorylase in rat hepatocytes S Aiston, LJ Hampson, C Arden, PB Iynedjian, L Agius Diabetologia 49, 174-182, 2006 | 47 | 2006 |
| Cell biology assessment of glucokinase mutations V62M and G72R in pancreatic β-cells: evidence for cellular instability of catalytic activity C Arden, A Trainer, N De La Iglesia, KT Scougall, AL Gloyn, AJ Lange, ... Diabetes 56 (7), 1773-1782, 2007 | 38 | 2007 |
| Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis FP Zummo, SI Krishnanda, M Georgiou, FPM O’Harte, V Parthsarathy, ... Autophagy 18 (4), 799-815, 2022 | 37 | 2022 |
| Glucagon induces translocation of glucokinase from the cytoplasm to the nucleus of hepatocytes by transfer between 6-phosphofructo 2-kinase/fructose 2, 6-bisphosphatase-2 and … KS Cullen, ZH Al-Oanzi, FPM O'Harte, L Agius, C Arden Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (6), 1123-1134, 2014 | 36 | 2014 |
| Glucose induces protein targeting to glycogen in hepatocytes by fructose 2, 6-bisphosphate-mediated recruitment of MondoA to the promoter JL Petrie, ZH Al-Oanzi, C Arden, SJ Tudhope, J Mann, J Kieswich, ... Molecular and Cellular Biology 33 (4), 725-738, 2013 | 35 | 2013 |
| A role for Glucagon-Like Peptide-1 in the regulation of β-cell autophagy C Arden Peptides 100, 85-93, 2018 | 33 | 2018 |
| Glucokinase regulatory protein is associated with mitochondria in hepatocytes C Arden, S Baltrusch, L Agius FEBS letters 580 (8), 2065-2070, 2006 | 33 | 2006 |
| Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation T Moonira, SS Chachra, BE Ford, S Marin, A Alshawi, NS Adam-Primus, ... Journal of Biological Chemistry 295 (10), 3330-3346, 2020 | 31 | 2020 |
| Pseudoislets as primary islet replacements for research: report on a symposium at King's College London, London UK SJ Persaud, C Arden, P Bergsten, AJ Bone, J Brown, S Dunmore, ... Islets 2 (4), 236-239, 2010 | 28 | 2010 |
| Opposite effects of a glucokinase activator and metformin on glucose‐regulated gene expression in hepatocytes ZH Al‐Oanzi, S Fountana, T Moonira, SJ Tudhope, JL Petrie, A Alshawi, ... Diabetes, Obesity and Metabolism 19 (8), 1078-1087, 2017 | 26 | 2017 |