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Qin Yan
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Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
E Querido, P Blanchette, Q Yan, T Kamura, M Morrison, D Boivin, ...
Genes & development 15 (23), 3104-3117, 2001
6262001
Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection
J Wei, MM Alfajaro, PC DeWeirdt, RE Hanna, WJ Lu-Culligan, WL Cai, ...
Cell 184 (1), 76-91. e13, 2021
558*2021
The retinoblastoma binding protein RBP2 is an H3K4 demethylase
RJ Klose, Q Yan, Z Tothova, K Yamane, H Erdjument-Bromage, P Tempst, ...
Cell 128 (5), 889-900, 2007
5082007
Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA
M Wang, C Mao, L Ouyang, Y Liu, W Lai, N Liu, Y Shi, L Chen, D Xiao, ...
Cell Death & Differentiation 26 (11), 2329-2343, 2019
4682019
Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer
J Cao, Q Yan
Frontiers in oncology 2, 26, 2012
4062012
The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2
T Kamura, MN Conrad, Q Yan, RC Conaway, JW Conaway
Genes & development 13 (22), 2928-2933, 1999
3511999
Immunological differences between primary and metastatic breast cancer
B Szekely, V Bossuyt, X Li, VB Wali, GA Patwardhan, C Frederick, A Silber, ...
Annals of Oncology 29 (11), 2232-2239, 2018
3242018
Cancer epigenetics, tumor immunity, and immunotherapy
J Cao, Q Yan
Trends in cancer 6 (7), 580-592, 2020
2672020
An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting
J Cao, L Wu, SM Zhang, M Lu, WKC Cheung, W Cai, M Gale, Q Xu, Q Yan
Nucleic acids research 44 (19), e149-e149, 2016
2662016
EGLN1/c-Myc induced lymphoid-specific helicase inhibits ferroptosis through lipid metabolic gene expression changes
Y Jiang, C Mao, R Yang, B Yan, Y Shi, X Liu, W Lai, Y Liu, X Wang, ...
Theranostics 7 (13), 3293, 2017
2552017
The Hypoxia-Inducible Factor 2α N-Terminal and C-Terminal Transactivation Domains Cooperate To Promote Renal Tumorigenesis In Vivo
Q Yan, S Bartz, M Mao, L Li, WG Kaelin Jr
Molecular and cellular biology 27 (6), 2092-2102, 2007
2412007
pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-κB agonist Card9 by CK2
H Yang, YA Minamishima, Q Yan, S Schlisio, BL Ebert, X Zhang, L Zhang, ...
Molecular cell 28 (1), 15-27, 2007
2212007
KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements
SM Zhang, WL Cai, X Liu, D Thakral, J Luo, LH Chan, MK McGeary, ...
Nature 598 (7882), 682-687, 2021
1992021
Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase
T Kamura, D Burian, Q Yan, SL Schmidt, WS Lane, E Querido, PE Branton, ...
Journal of Biological Chemistry 276 (32), 29748-29753, 2001
1892001
Epigenetic regulation by lysine demethylase 5 (KDM5) enzymes in cancer
LP Blair, J Cao, MR Zou, J Sayegh, Q Yan
Cancers 3 (1), 1383-1404, 2011
1842011
The von Hippel–Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C
X Niu, T Zhang, L Liao, L Zhou, DJ Lindner, M Zhou, B Rini, Q Yan, ...
Oncogene 31 (6), 776-786, 2012
1732012
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1
W Lin, J Cao, J Liu, ML Beshiri, Y Fujiwara, J Francis, AD Cherniack, ...
Proceedings of the National Academy of Sciences 108 (33), 13379-13386, 2011
1612011
Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis
YC Teng, CF Lee, YS Li, YR Chen, PW Hsiao, MY Chan, FM Lin, ...
Cancer research 73 (15), 4711-4721, 2013
1582013
Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen
J Sayegh, J Cao, MR Zou, A Morales, LP Blair, M Norcia, D Hoyer, ...
Journal of Biological Chemistry 288 (13), 9408-9417, 2013
1572013
Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53
P Blanchette, CY Cheng, Q Yan, G Ketner, DA Ornelles, T Dobner, ...
Molecular and cellular biology 24 (21), 9619-9629, 2004
1502004
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