Snake venomics of African spitting cobras: toxin composition and assessment of congeneric cross-reactivity of the pan-African EchiTAb-Plus-ICP antivenom by antivenomics and … D Petras, L Sanz, A Segura, M Herrera, M Villalta, D Solano, M Vargas, ... Journal of proteome research 10 (3), 1266-1280, 2011 | 240 | 2011 |
Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms G León, M Herrera, Á Segura, M Villalta, M Vargas, JM Gutiérrez Toxicon 76, 63-76, 2013 | 180 | 2013 |
Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: state-of-the-art and challenges ahead JM Gutiérrez, G Solano, D Pla, M Herrera, Á Segura, M Vargas, M Villalta, ... Toxins 9 (5), 163, 2017 | 165 | 2017 |
Immune response towards snake venoms G León, L Sánchez, A Hernández, M Villalta, M Herrera, A Segura, ... Inflammation & Allergy-Drug Targets (Formerly Current Drug Targets …, 2011 | 161 | 2011 |
Preclinical assessment of the neutralizing capacity of antivenoms produced in six Latin American countries against medically-relevant Bothrops snake venoms A Segura, MC Castillo, V Núñez, A Yarlequé, LRC Gonçalves, M Villalta, ... Toxicon 56 (6), 980-989, 2010 | 119 | 2010 |
Phylovenomics of Daboia russelii across the Indian subcontinent. Bioactivities and comparative in vivo neutralization and in vitro third-generation antivenomics of antivenoms … D Pla, L Sanz, S Quesada-Bernat, M Villalta, J Baal, MAW Chowdhury, ... Journal of proteomics 207, 103443, 2019 | 116 | 2019 |
Current technology for the industrial manufacture of snake antivenoms G León, M Vargas, Á Segura, M Herrera, M Villalta, A Sánchez, G Solano, ... Toxicon 151, 63-73, 2018 | 98 | 2018 |
Impact of Regional Variation in Bothrops asper Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches JM Gutiérrez, L Sanz, M Flores-Díaz, L Figueroa, M Madrigal, M Herrera, ... Journal of Proteome Research 9 (1), 564-577, 2010 | 95 | 2010 |
Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP®) for the treatment of viper envenoming in sub-Saharan Africa A Segura, M Villalta, M Herrera, G Leon, R Harrison, N Durfa, A Nasidi, ... Toxicon 55 (2-3), 369-374, 2010 | 85 | 2010 |
Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice M Rivel, D Solano, M Herrera, M Vargas, M Villalta, Á Segura, AS Arias, ... Toxicon 119, 171-179, 2016 | 84 | 2016 |
Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics JM Gutiérrez, G Solano, D Pla, M Herrera, Á Segura, M Villalta, M Vargas, ... Toxicon 69, 168-179, 2013 | 77 | 2013 |
Snake venomics and antivenomics of Protobothrops mucrosquamatus and Viridovipera stejnegeri from Taiwan: keys to understand the variable immune response in horses M Villalta, D Pla, SL Yang, L Sanz, A Segura, M Vargas, PY Chen, ... Journal of proteomics 75 (18), 5628-5645, 2012 | 77 | 2012 |
Assessment of snake antivenom purity by comparing physicochemical and immunochemical methods Á Segura, M Herrera, M Villalta, M Vargas, JM Gutiérrez, G León Biologicals 41 (2), 93-97, 2013 | 76 | 2013 |
Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: Role of neurotoxic and procoagulant effects in … M Herrera, J Fernández, M Vargas, M Villalta, Á Segura, G León, ... Journal of proteomics 75 (7), 2128-2140, 2012 | 75 | 2012 |
Preclinical Evaluation of Caprylic Acid-Fractionated IgG Antivenom for the Treatment of Taipan (Oxyuranus scutellatus) Envenoming in Papua New Guinea M Vargas, A Segura, M Herrera, M Villalta, R Estrada, M Cerdas, O Paiva, ... PLoS neglected tropical diseases 5 (5), e1144, 2011 | 62 | 2011 |
Antivenomic assessment of the immunological reactivity of EchiTAb-Plus-ICP, an antivenom for the treatment of snakebite envenoming in sub-Saharan Africa JJ Calvete, P Cid, L Sanz, M Villalta, M Herrera, G León, R Harrison, ... The American journal of tropical medicine and hygiene 82 (6), 1194, 2010 | 61 | 2010 |
Proteomic, toxicological and immunogenic characterization of Mexican west-coast rattlesnake (Crotalus basiliscus) venom and its immunological relatedness with the venom of … Á Segura, M Herrera, FR Mares, C Jaime, A Sánchez, M Vargas, ... Journal of Proteomics 158, 62-72, 2017 | 53 | 2017 |
Study of the design and analytical properties of the lethality neutralization assay used to estimate antivenom potency against Bothrops asper snake venom G Solano, Á Segura, M Herrera, A Gómez, M Villalta, JM Gutiérrez, ... Biologicals 38 (5), 577-585, 2010 | 48 | 2010 |
In Vitro Tests for Assessing the Neutralizing Ability of Snake Antivenoms: Toward the 3Rs Principles JM Gutiérrez, M Vargas, Á Segura, M Herrera, M Villalta, G Solano, ... Frontiers in Immunology 11, 617429, 2021 | 42 | 2021 |
Development of a new polyspecific antivenom for snakebite envenoming in Sri Lanka: Analysis of its preclinical efficacy as compared to a currently available antivenom M Villalta, A Sánchez, M Herrera, M Vargas, Á Segura, M Cerdas, ... Toxicon 122, 152-159, 2016 | 38 | 2016 |