Richard A. Engh

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	Toate	Din 2020
Referințe bibliografice	13398	1503
h-index	50	21
i10-index	105	42

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Hans BrandstetterUniversity of SalzburgAdresă de e-mail confirmată pe sbg.ac.at
Karl-Peter HopfnerLudwig-Maximilians-Universität MünchenAdresă de e-mail confirmată pe genzentrum.lmu.de
Nikolas von BubnoffAdresă de e-mail confirmată pe uksh.de
Graham FlemingUniversity of California Berkeley | Lawrence Berkeley National LaboratoryAdresă de e-mail confirmată pe lbl.gov
Osman GaniUniversity of OsloAdresă de e-mail confirmată pe farmasi.uio.no
John S. Mjøen SvendsenProfessor i organisk kjemi, Universitetet i TromsøAdresă de e-mail confirmată pe uit.no
Milton T. StubbsAdresă de e-mail confirmată pe biochemtech.uni-halle.de
Andrey KarshikoffretiredAdresă de e-mail confirmată pe bio21.bas.bg
Lin X. ChenProfessor of Chemistry, Northwestern University/Distinguished Fellow, Argonne National LaboratoryAdresă de e-mail confirmată pe northwestern.edu
Guy GeorgesRoche Innovation Center MunichAdresă de e-mail confirmată pe roche.com
dusan turkJosef Stefan InstituteAdresă de e-mail confirmată pe ijs.si
Maria Joao RomaoFaculdade de Ciencias e Tecnologia, NOVA - UCIBIO-i4HBAdresă de e-mail confirmată pe fct.unl.pt
Martin RenatusAssociate Director, Novartis PharmaAdresă de e-mail confirmată pe novartis.com
Balmukund ThakkarUniversity of TromsøAdresă de e-mail confirmată pe uit.no
Dr. Rama Krishna KanchaOsmania University, Hyderabad, IndiaAdresă de e-mail confirmată pe osmania.ac.in
Johan IsakssonUiT - the Arctic University of NorwayAdresă de e-mail confirmată pe uit.no
P D J GrootenhuisVertex PharmaceuticalsAdresă de e-mail confirmată pe vrtx.com
Stefan BonnProfessor for Medical Systems Biology, UKE and ZMN HamburgAdresă de e-mail confirmată pe uke.de
Bjarte Aarmo LundUniversitetet i TromsøAdresă de e-mail confirmată pe uit.no
Manfred SchwaigerHead of Operations, pRED Oncology, F. Hoffman-LaRoche Ltd.Adresă de e-mail confirmată pe roche.com

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Richard A. Engh

Professor of Chemistry, UiT the Arctic University of Norway

Adresă de e-mail confirmată pe uit.no

Protein crystallography enzyme inhibition drug design


Titlu Sortați după descrierea bibliografică Sortați după an Sortați după titlu	Citat de Citat de	Anul
Accurate bond and angle parameters for X-ray protein structure refinement RA Engh, R Huber Foundations of Crystallography 47 (4), 392-400, 1991	3337	1991
The 2.0 AX‐ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases. W Bode, R Engh, D Musil, U Thiele, R Huber, A Karshikov, J Brzin, J Kos, ... The EMBO journal 7 (8), 2593-2599, 1988	780	1988
The refined 2.15 AX‐ray crystal structure of human liver cathepsin B: the structural basis for its specificity. D Musil, D Zucic, D Turk, RA Engh, I Mayr, R Huber, T Popovic, V Turk, ... The EMBO journal 10 (9), 2321-2330, 1991	778	1991
Crystal Structure of the Xanthine Oxidase-Related Aldehyde Oxido-Reductase from D. gigas MJ Romao, M Archer, I Moura, JJG Moura, J LeGall, R Engh, M Schneider, ... Science 270 (5239), 1170-1176, 1995	604	1995
Phosphotransferase and substrate binding mechanism of the cAMP‐dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex … D Bossemeyer, RA Engh, V Kinzel, H Ponstingl, R Huber The EMBO journal 12 (3), 849-859, 1993	490	1993
International Tables for Crystallography, Vol. F, edited by MG Rossmann & E. Arnold RA Engh, R Huber Dordrecht: Kluwer Academic Publishers, 2001	390	2001
Chalcone derivatives antagonize interactions between the human oncoprotein MDM2 and p53 R Stoll, C Renner, S Hansen, S Palme, C Klein, A Belling, W Zeslawski, ... Biochemistry 40 (2), 336-344, 2001	381	2001
X-ray structure of active site-inhibited clotting factor Xa: implications for drug design and substrate recognition H Brandstetter, A Kühne, W Bode, R Huber, W von der Saal, ... Journal of Biological Chemistry 271 (47), 29988-29992, 1996	353	1996
Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89: structural implications … RA Engh, A Girod, V Kinzel, R Huber, D Bossemeyer Journal of Biological Chemistry 271 (42), 26157-26164, 1996	343	1996
Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius KP Hopfner, A Eichinger, RA Engh, F Laue, W Ankenbauer, R Huber, ... Proceedings of the National Academy of Sciences 96 (7), 3600-3605, 1999	288	1999
Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential L Prade, RA Engh, A Girod, V Kinzel, R Huber, D Bossemeyer Structure 5 (12), 1627-1637, 1997	231	1997
Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity C Breitenlechner, M Gaßel, H Hidaka, V Kinzel, R Huber, RA Engh, ... Structure 11 (12), 1595-1607, 2003	226	2003
Protein kinase inhibition of clinically important staurosporine analogues OA Gani, RA Engh Natural product reports 27 (4), 489-498, 2010	178	2010
The 1.8-Å crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition H Brandstetter, F Grams, D Glitz, A Lang, R Huber, W Bode, HW Krell, ... Journal of Biological Chemistry 276 (20), 17405-17412, 2001	164	2001
Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding KP Hopfner, A Lang, A Karcher, K Sichler, E Kopetzki, H Brandstetter, ... Structure 7 (8), 989-996, 1999	146	1999
Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib RK Kancha, N von Bubnoff, N Bartosch, C Peschel, RA Engh, J Duyster PloS one 6 (10), e26760, 2011	142	2011
Structure-based optimization of novel azepane derivatives as PKB inhibitors CB Breitenlechner, T Wegge, L Berillon, K Graul, K Marzenell, WG Friebe, ... Journal of medicinal chemistry 47 (6), 1375-1390, 2004	142	2004
Lysine 156 promotes the anomalous proenzyme activity of tPA: X‐ray crystal structure of single‐chain human tPA M Renatus, RA Engh, MT Stubbs, R Huber, S Fischer, U Kohnert, W Bode The EMBO journal, 1997	142	1997
Structural aspects of protein kinase control—role of conformational flexibility RA Engh, D Bossemeyer Pharmacology & therapeutics 93 (2-3), 99-111, 2002	137	2002
The interaction of insulin‐like growth factor‐I with the N‐terminal domain of IGFBP‐5 W Żesławski, HG Beisel, M Kamionka, W Kalus, RA Engh, R Huber, ... The EMBO journal, 2001	134	2001

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