| sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance A Kaur, MR Webster, K Marchbank, R Behera, A Ndoye, CH Kugel, ... Nature 532 (7598), 250-254, 2016 | 399 | 2016 |
| Remodeling of the collagen matrix in aging skin promotes melanoma metastasis and affects immune cell motility A Kaur, BL Ecker, SM Douglass, CH Kugel III, MR Webster, FV Almeida, ... Cancer discovery 9 (1), 64-81, 2019 | 367 | 2019 |
| Age correlates with response to anti-PD1, reflecting age-related differences in intratumoral effector and regulatory T-cell populations CH Kugel III, SM Douglass, MR Webster, A Kaur, Q Liu, X Yin, SA Weiss, ... Clinical Cancer Research 24 (21), 5347-5356, 2018 | 344 | 2018 |
| Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2 MP O'Connell, K Marchbank, MR Webster, AA Valiga, A Kaur, A Vultur, ... Cancer discovery 3 (12), 1378-1393, 2013 | 260 | 2013 |
| PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion MC Caino, JC Ghosh, YC Chae, V Vaira, DB Rivadeneira, A Faversani, ... Proceedings of the National Academy of Sciences 112 (28), 8638-8643, 2015 | 218 | 2015 |
| Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion H Ahmadzadeh, MR Webster, R Behera, AM Jimenez Valencia, D Wirtz, ... Proceedings of the National Academy of Sciences 114 (9), E1617-E1626, 2017 | 210 | 2017 |
| Age-related changes in HAPLN1 increase lymphatic permeability and affect routes of melanoma metastasis BL Ecker, A Kaur, SM Douglass, MR Webster, FV Almeida, GE Marino, ... Cancer discovery 9 (1), 82-95, 2019 | 134 | 2019 |
| Stromal changes in the aged lung induce an emergence from melanoma dormancy ME Fane, Y Chhabra, GM Alicea, DA Maranto, SM Douglass, MR Webster, ... Nature 606 (7913), 396-405, 2022 | 122 | 2022 |
| Changes in aged fibroblast lipid metabolism induce age-dependent melanoma cell resistance to targeted therapy via the fatty acid transporter FATP2 GM Alicea, VW Rebecca, AR Goldman, ME Fane, SM Douglass, ... Cancer discovery 10 (9), 1282-1295, 2020 | 112 | 2020 |
| Role of IL-6 in an IL-10 and IL-4 double knockout mouse model uniquely susceptible to acetaminophen-induced liver injury M Bourdi, DP Eiras, MP Holt, MR Webster, TP Reilly, KD Welch, LR Pohl Chemical research in toxicology 20 (2), 208-216, 2007 | 102 | 2007 |
| Wnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells. MR Webster, M Xu, KA Kinzler, A Kaur, J Appleton, MP O’Connell, ... Pigment Cell Melanoma Res. 28 (2), 184-195, 2015 | 99 | 2015 |
| The Wnts of change: How Wnts regulate phenotype switching in melanoma MR Webster, CH Kugel III, AT Weeraratna Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1856 (2), 244-251, 2015 | 96 | 2015 |
| A Wnt-er migration: the confusing role of β-catenin in melanoma metastasis MR Webster, AT Weeraratna Science signaling 6 (268), pe11-pe11, 2013 | 93 | 2013 |
| Paradoxical role for wild-type p53 in driving therapy resistance in melanoma MR Webster, ME Fane, GM Alicea, S Basu, AV Kossenkov, GE Marino, ... Molecular cell 77 (3), 633-644. e5, 2020 | 70 | 2020 |
| In the Wnt-er of life: Wnt signalling in melanoma and ageing A Kaur, MR Webster, AT Weeraratna British journal of cancer 115 (11), 1273-1279, 2016 | 68 | 2016 |
| Novel protein kinase C-mediated control of Orai1 function in invasive melanoma R Hooper, X Zhang, M Webster, C Go, J Kedra, K Marchbank, DL Gill, ... Molecular and cellular biology 35 (16), 2790-2798, 2015 | 64 | 2015 |
| ATG5 mediates a positive feedback loop between Wnt signaling and autophagy in melanoma A Ndoye, A Budina-Kolomets, CH Kugel III, MR Webster, A Kaur, ... Cancer research 77 (21), 5873-5885, 2017 | 41 | 2017 |
| Inhibition of age-related therapy resistance in melanoma by rosiglitazone-mediated induction of Klotho R Behera, A Kaur, MR Webster, S Kim, A Ndoye, CH Kugel III, GM Alicea, ... Clinical Cancer Research 23 (12), 3181-3190, 2017 | 41 | 2017 |
| HSP70 inhibition limits FAK-dependent invasion and enhances the response to melanoma treatment with BRAF inhibitors A Budina-Kolomets, MR Webster, JIJ Leu, M Jennis, C Krepler, A Guerrini, ... Cancer research 76 (9), 2720-2730, 2016 | 39 | 2016 |
| Remodeling of the collagen matrix in aging skin promotes melanoma metastasis and affects immune cell motility. Cancer Discov. 2019; 9: 64–81. doi: 10.1158/2159-8290 A Kaur, BL Ecker, SM Douglass, CH Kugel, MR Webster, FV Almeida, ... CD-18-0193.[Europe PMC free article][Abstract][CrossRef][Academic Search], 0 | 39 | |
Xiaowei XuProfessor at University of Pennsylvania, Departments of Pathology and DermatologyAdresă de e-mail confirmată pe pennmedicine.upenn.edu
