PKB/Akt mediates cell-cycle progression by phosphorylation of p27Kip1 at threonine 157 and modulation of its cellular localization I Shin, FM Yakes, F Rojo, NY Shin, AV Bakin, J Baselga, CL Arteaga Nature medicine 8 (10), 1145-1152, 2002 | 997 | 2002 |
Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors R Bianco, I Shin, CA Ritter, FM Yakes, A Basso, N Rosen, J Tsurutani, ... Oncogene 22 (18), 2812-2822, 2003 | 580 | 2003 |
Type I transforming growth factor β receptor binds to and activates phosphatidylinositol 3-kinase JY Yi, I Shin, CL Arteaga Journal of Biological Chemistry 280 (11), 10870-10876, 2005 | 321 | 2005 |
Transforming growth factor β enhances epithelial cell survival via Akt-dependent regulation of FKHRL1 I Shin, AV Bakin, U Rodeck, A Brunet, CL Arteaga Molecular biology of the cell 12 (11), 3328-3339, 2001 | 233 | 2001 |
The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest JB Kim, JH Yu, E Ko, KW Lee, AK Song, SY Park, I Shin, W Han, DY Noh Phytomedicine 17 (6), 436-440, 2010 | 173 | 2010 |
Activated type I TGFβ receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression RS Muraoka-Cook, I Shin, JY Yi, E Easterly, MH Barcellos-Hoff, ... Oncogene 25 (24), 3408-3423, 2006 | 167 | 2006 |
Reduction of cytosolic p27Kip1 inhibits cancer cell motility, survival, and tumorigenicity FY Wu, SE Wang, ME Sanders, I Shin, F Rojo, J Baselga, CL Arteaga Cancer research 66 (4), 2162-2172, 2006 | 165 | 2006 |
Glut1 promotes cell proliferation, migration and invasion by regulating epidermal growth factor receptor and integrin signaling in triple-negative breast cancer cells S Oh, H Kim, KS Nam, I Shin BMB reports 50 (3), 132, 2017 | 151 | 2017 |
CD44 regulates cell proliferation, migration, and invasion via modulation of c-Src transcription in human breast cancer cells KS Nam, S Oh, K Lee, S Yoo, I Shin Cellular signalling 27 (9), 1882-1894, 2015 | 144 | 2015 |
HER2/Neu (ErbB2) signaling to Rac1-Pak1 is temporally and spatially modulated by transforming growth factor β SE Wang, I Shin, FY Wu, DB Friedman, CL Arteaga Cancer research 66 (19), 9591-9600, 2006 | 132 | 2006 |
Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells HS Seo, HS Choi, SR Kim, YK Choi, SM Woo, I Shin, JK Woo, SY Park, ... Molecular and cellular biochemistry, 1-16, 2012 | 131 | 2012 |
Phosphorylation of p27Kip1 at Thr-157 Interferes with its association with importin α during G1 and prevents nuclear re-entry I Shin, J Rotty, FY Wu, CL Arteaga Journal of Biological Chemistry 280 (7), 6055-6063, 2005 | 114 | 2005 |
Transforming growth factor β (TGF-β)-Smad target gene protein tyrosine phosphatase receptor type kappa is required for TGF-β function SE Wang, FY Wu, I Shin, S Qu, CL Arteaga Molecular and cellular biology 25 (11), 4703-4715, 2005 | 107 | 2005 |
ECM1 regulates tumor metastasis and CSC-like property through stabilization of β-catenin KM Lee, K Nam, S Oh, J Lim, RK Kim, D Shim, JH Choi, SJ Lee, JH Yu, ... Oncogene 34 (50), 6055-6065, 2015 | 105 | 2015 |
A rapid and simple fabrication method for 3-dimensional circular microfluidic channel using metal wire removal process SH Song, CK Lee, TJ Kim, I Shin, SC Jun, HI Jung Microfluidics and Nanofluidics 9 (2), 533-540, 2010 | 105 | 2010 |
Regulation of cell proliferation and migration by keratin19-induced nuclear import of early growth response-1 in breast cancer cells J Ju, W Yang, K Lee, S Oh, KS Nam, S Shim, SY Shin, MC Gye, IS Chu, ... Clinical cancer research 19 (16), 4335-4346, 2013 | 87 | 2013 |
Induction of apoptotic cell death by phytoestrogens by up-regulating the levels of phospho-p53 and p21 in normal and malignant estrogen receptor α–negative breast cells HS Seo, J Ju, K Jang, I Shin Nutrition research 31 (2), 139-146, 2011 | 83 | 2011 |
Phosphatidic Acid-induced Elevation of Intracellular Ca2+ Is Mediated by RhoA and H2O2in Rat-2 Fibroblasts ZW Lee, SM Kweon, BC Kim, SH Leem, I Shin, JH Kim, KS Ha Journal of Biological Chemistry 273 (21), 12710-12715, 1998 | 76 | 1998 |
Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling K Lee, K Nam, S Oh, J Lim, YP Kim, JW Lee, JH Yu, SH Ahn, SB Kim, ... Breast Cancer Research 16, 1-17, 2014 | 73 | 2014 |
Proapoptotic activity of cell-permeable anti-Akt single-chain antibodies I Shin, J Edl, S Biswas, PC Lin, R Mernaugh, CL Arteaga Cancer research 65 (7), 2815-2824, 2005 | 72 | 2005 |