Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval D Hwang, JD Ramsey, AV Kabanov Advanced drug delivery reviews 156, 80-118, 2020 | 481 | 2020 |
Silymarin-loaded solid nanoparticles provide excellent hepatic protection: physicochemical characterization and in vivo evaluation KY Yang, DH Hwang, AM Yousaf, DW Kim, YJ Shin, ON Bae, YII Kim, ... International journal of nanomedicine, 3333-3343, 2013 | 109 | 2013 |
scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy JK Ocasio, B Babcock, D Malawsky, SJ Weir, L Loo, JM Simon, MJ Zylka, ... Nature communications 10 (1), 5829, 2019 | 107 | 2019 |
High-capacity poly (2-oxazoline) formulation of TLR 7/8 agonist extends survival in a chemo-insensitive, metastatic model of lung adenocarcinoma N Vinod, D Hwang, SH Azam, AED Van Swearingen, E Wayne, ... Science advances 6 (25), eaba5542, 2020 | 59 | 2020 |
Drug‐dependent morphological transitions in spherical and worm‐like polymeric micelles define stability and pharmacological performance of micellar drugs C Lim, JD Ramsey, D Hwang, SCM Teixeira, CD Poon, JD Strauss, ... Small 18 (4), 2103552, 2022 | 55 | 2022 |
ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation PY Lang, GJ Nanjangud, M Sokolsky-Papkov, C Shaw, D Hwang, ... Development 143 (21), 4038-4052, 2016 | 54 | 2016 |
Poly (2-oxazoline) nanoparticle delivery enhances the therapeutic potential of vismodegib for medulloblastoma by improving CNS pharmacokinetics and reducing systemic toxicity D Hwang, T Dismuke, A Tikunov, EP Rosen, JR Kagel, JD Ramsey, C Lim, ... Nanomedicine: Nanotechnology, Biology and Medicine 32, 102345, 2021 | 51 | 2021 |
Cheminformatics-driven discovery of polymeric micelle formulations for poorly soluble drugs VM Alves, D Hwang, E Muratov, M Sokolsky-Papkov, E Varlamova, ... Science Advances 5 (6), eaav9784, 2019 | 47 | 2019 |
A novel solid dispersion system for natural product-loaded medicine: silymarin-loaded solid dispersion with enhanced oral bioavailability and hepatoprotective activity DH Hwang, YI Kim, KH Cho, BK Poudel, JY Choi, DW Kim, YJ Shin, ... Journal of Microencapsulation 31 (7), 619-626, 2014 | 41 | 2014 |
Novel poly (2-oxazoline) block copolymer with aromatic heterocyclic side chains as a drug delivery platform D Hwang, JD Ramsey, N Makita, C Sachse, R Jordan, ... Journal of Controlled Release 307, 261-271, 2019 | 39 | 2019 |
Enhancing CDK4/6 inhibitor therapy for medulloblastoma using nanoparticle delivery and scRNA-seq–guided combination with sapanisertib C Lim, T Dismuke, D Malawsky, JD Ramsey, D Hwang, VL Godfrey, ... Science advances 8 (4), eabl5838, 2022 | 29 | 2022 |
Inhibition of UCH-L1 deubiquitinating activity with two forms of LDN-57444 has anti-invasive effects in metastatic carcinoma cells E Kobayashi, D Hwang, A Bheda-Malge, CB Whitehurst, AV Kabanov, ... International journal of molecular sciences 20 (15), 3733, 2019 | 27 | 2019 |
High-dose paclitaxel and its combination with CSF1R inhibitor in polymeric micelles for chemoimmunotherapy of triple negative breast cancer C Lim, D Hwang, M Yazdimamaghani, HM Atkins, H Hyun, Y Shin, ... Nano Today 51, 101884, 2023 | 21 | 2023 |
Bioequivalence assessment of high-capacity polymeric micelle nanoformulation of paclitaxel and Abraxane® in rodent and non-human primate models using a stable isotope tracer assay D Hwang, N Vinod, SL Skoczen, JD Ramsey, KS Snapp, SA Montgomery, ... Biomaterials 278, 121140, 2021 | 21 | 2021 |
Genetically modified macrophages accomplish targeted gene delivery to the inflamed brain in transgenic Parkin Q311X (A) mice: importance of administration routes MJ Haney, Y Zhao, J Fay, H Duhyeong, M Wang, H Wang, Z Li, YZ Lee, ... Scientific Reports 10 (1), 11818, 2020 | 17 | 2020 |
Antiapoptotic Bcl-2 family proteins BCL-xL and MCL-1 integrate neural progenitor survival and proliferation during postnatal cerebellar neurogenesis KA Veleta, AH Cleveland, BR Babcock, YW He, D Hwang, ... Cell Death & Differentiation 28 (5), 1579-1592, 2021 | 15 | 2021 |
Nanoformulated Remdesivir with Extremely Low Content of Poly (2‐oxazoline)‐Based Stabilizer for Aerosol Treatment of COVID‐19 JD Ramsey, IE Stewart, EA Madden, C Lim, D Hwang, MT Heise, ... Macromolecular Bioscience 22 (8), 2200056, 2022 | 12 | 2022 |
Tumor microenvironment immunomodulation by nanoformulated TLR 7/8 agonist and PI3k delta inhibitor enhances therapeutic benefits of radiotherapy M Yazdimamaghani, OV Kolupaev, C Lim, D Hwang, SJ Laurie, ... Biomaterials 312, 122750, 2025 | 4 | 2025 |
Combination of polymeric micelle formulation of TGFβ receptor inhibitors and paclitaxel produces consistent response across different mouse models of Triple‐negative breast cancer N Vinod, D Hwang, SC Fussell, TC Owens, OC Tofade, TS Benefield, ... Bioengineering & Translational Medicine, e10681, 2024 | 1 | 2024 |
Poly (2‐oxazoline)‐Based Polyplexes as a PEG‐Free Plasmid DNA Delivery Platform DN Yamaleyeva, N Makita, D Hwang, MJ Haney, R Jordan, AV Kabanov Macromolecular Bioscience 23 (11), 2300177, 2023 | 1 | 2023 |