Transporters at CNS barrier sites: obstacles or opportunities for drug delivery? L Sanchez-Covarrubias, LM Slosky, BJ Thompson, TP Davis, ... Current pharmaceutical design 20 (10), 1422-1449, 2014 | 286 | 2014 |
Biased allosteric modulators: new frontiers in GPCR drug discovery LM Slosky, MG Caron, LS Barak Trends in Pharmacological Sciences 42 (4), 283-299, 2021 | 149 | 2021 |
β-arrestin-biased allosteric modulator of NTSR1 selectively attenuates addictive behaviors LM Slosky, Y Bai, K Toth, C Ray, LK Rochelle, A Badea, ... Cell 181 (6), 1364-1379. e14, 2020 | 119 | 2020 |
Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood–brain barrier: relevance to CNS drug delivery BJ Thompson, L Sanchez-Covarrubias, LM Slosky, Y Zhang, ... Journal of Cerebral Blood Flow & Metabolism 34 (4), 699-707, 2014 | 89 | 2014 |
Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor–dependent mechanism LM Slosky, BJ Thompson, L Sanchez-Covarrubias, Y Zhang, ... Molecular pharmacology 84 (5), 774-786, 2013 | 67 | 2013 |
Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation SA Grenald, TM Doyle, H Zhang, LM Slosky, Z Chen, TM Largent-Milnes, ... Pain 158 (9), 1733-1742, 2017 | 64 | 2017 |
Use of animal models in understanding cancer-induced bone pain LM Slosky, TM Largent-Milnes, TW Vanderah Cancer growth and metastasis 8, CGM. S21215, 2015 | 58 | 2015 |
Angiotensin-(1-7)/Mas receptor as an antinociceptive agent in cancer-induced bone pain BL Forte, LM Slosky, H Zhang, MR Arnold, WD Staatz, M Hay, ... Pain 157 (12), 2709-2721, 2016 | 57 | 2016 |
P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac L Sanchez-Covarrubias, LM Slosky, BJ Thompson, Y Zhang, ... PloS one 9 (2), e88516, 2014 | 57 | 2014 |
The cystine/glutamate antiporter system xc− drives breast tumor cell glutamate release and cancer-induced bone pain LM Slosky, NM BassiriRad, AM Symons, M Thompson, T Doyle, BL Forte, ... Pain 157 (11), 2605-2616, 2016 | 42 | 2016 |
Discovery of β-arrestin biased, orally bioavailable, and CNS penetrant neurotensin receptor 1 (NTR1) allosteric modulators AB Pinkerton, S Peddibhotla, F Yamamoto, LM Slosky, Y Bai, P Maloney, ... Journal of medicinal chemistry 62 (17), 8357-8363, 2019 | 39 | 2019 |
Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator BE Krumm, JF DiBerto, RHJ Olsen, HJ Kang, ST Slocum, S Zhang, ... Biochemistry 62 (7), 1233-1248, 2023 | 37 | 2023 |
Therapeutic potential of peroxynitrite decomposition catalysts: a patent review LM Slosky, TW Vanderah Expert Opinion on Therapeutic Patents 25 (4), 443-466, 2015 | 27 | 2015 |
A comparative study of the retention and lethality of the first and second generation arthropod protein markers LM Slosky, EJ Hoffmann, JR Hagler Entomologia Experimentalis et Applicata 144 (2), 165-171, 2012 | 16 | 2012 |
Ghrelin receptor antagonism of hyperlocomotion in cocaine‐sensitized mice requires βarrestin‐2 K Toth, LM Slosky, TF Pack, NM Urs, P Boone, L Mao, D Abraham, ... Synapse 72 (1), e22012, 2018 | 12 | 2018 |
Establishment of multi-stage intravenous self-administration paradigms in mice LM Slosky, A Pires, Y Bai, NB Clark, ER Hauser, JD Gross, F Porkka, ... Scientific reports 12 (1), 21422, 2022 | 9 | 2022 |
Encoding the β-arrestin trafficking fate of ghrelin receptor GHSR1a: C-tail-independent molecular determinants in GPCRs K Toth, K Nagi, LM Slosky, L Rochelle, C Ray, S Kaur, SK Shenoy, ... ACS Pharmacology & Translational Science 2 (4), 230-246, 2019 | 9 | 2019 |
Discovery of a functionally selective ghrelin receptor (GHSR1a) ligand for modulating brain dopamine JD Gross, DW Kim, Y Zhou, D Jansen, LM Slosky, NB Clark, CR Ray, ... Proceedings of the National Academy of Sciences 119 (10), e2112397119, 2022 | 8 | 2022 |
Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated excitation of ventral tegmental area dopamine neurons and dopamine release in the nucleus accumbens SM Singhal, V Zell, L Faget, LM Slosky, LS Barak, MG Caron, ... Neuropharmacology 234, 109544, 2023 | 6 | 2023 |
β-arrestin-biased Allosteric Modulator of Neurotensin Receptor 1 Reduces Ethanol Drinking and Responses to Ethanol Administration in Rodents GB Gereau, D Zhou, K Van Voorhies, RE Tyler, J Campbell, JG Murray, ... bioRxiv, 2024 | 3 | 2024 |