Molecular signature of CD8+ T cell exhaustion during chronic viral infection EJ Wherry, SJ Ha, SM Kaech, WN Haining, S Sarkar, V Kalia, ... Immunity 27 (4), 670-684, 2007 | 2506 | 2007 |
Effector and memory T-cell differentiation: implications for vaccine development SM Kaech, EJ Wherry, R Ahmed Nature Reviews Immunology 2 (4), 251-262, 2002 | 2506 | 2002 |
Lineage relationship and protective immunity of memory CD8 T cell subsets EJ Wherry, V Teichgräber, TC Becker, D Masopust, SM Kaech, R Antia, ... Nature immunology 4 (3), 225-234, 2003 | 2416 | 2003 |
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells SM Kaech, JT Tan, EJ Wherry, BT Konieczny, CD Surh, R Ahmed Nature immunology 4 (12), 1191-1198, 2003 | 2363 | 2003 |
Inflammation directs memory precursor and short-lived effector CD8+ T cell fates via the graded expression of T-bet transcription factor NS Joshi, W Cui, A Chandele, HK Lee, DR Urso, J Hagman, L Gapin, ... Immunity 27 (2), 281-295, 2007 | 2246 | 2007 |
Transcriptional control of effector and memory CD8+ T cell differentiation SM Kaech, W Cui Nature Reviews Immunology 12 (11), 749-761, 2012 | 1881 | 2012 |
Mitochondrial DNA stress primes the antiviral innate immune response P West Biophysical Journal 108 (2), 3a, 2015 | 1671 | 2015 |
Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naive cells SM Kaech, R Ahmed Nature immunology 2 (5), 415-422, 2001 | 1661 | 2001 |
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin AM Intlekofer, N Takemoto, EJ Wherry, SA Longworth, JT Northrup, ... Nature immunology 6 (12), 1236-1244, 2005 | 1524 | 2005 |
Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ... Cell 162 (6), 1217-1228, 2015 | 1373 | 2015 |
Molecular and functional profiling of memory CD8 T cell differentiation SM Kaech, S Hemby, E Kersh, R Ahmed Cell 111 (6), 837-851, 2002 | 1259 | 2002 |
Metabolic instruction of immunity MD Buck, RT Sowell, SM Kaech, EL Pearce Cell 169 (4), 570-586, 2017 | 1109 | 2017 |
Estimating the precursor frequency of naive antigen-specific CD8 T cells JN Blattman, R Antia, DJD Sourdive, X Wang, SM Kaech, ... The Journal of experimental medicine 195 (5), 657-664, 2002 | 839 | 2002 |
Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection SM Kaech, EJ Wherry Immunity 27 (3), 393-405, 2007 | 819 | 2007 |
Transcriptional repressor Blimp-1 promotes CD8+ T cell terminal differentiation and represses the acquisition of central memory T cell properties RL Rutishauser, GA Martins, S Kalachikov, A Chandele, IA Parish, ... Immunity 31 (2), 296-308, 2009 | 760 | 2009 |
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes RJ Perry, JPG Camporez, R Kursawe, PM Titchenell, D Zhang, CJ Perry, ... Cell 160 (4), 745-758, 2015 | 757 | 2015 |
Heterologous immunity provides a potent barrier to transplantation tolerance AB Adams, MA Williams, TR Jones, N Shirasugi, MM Durham, SM Kaech, ... The Journal of clinical investigation 111 (12), 1887-1895, 2003 | 751 | 2003 |
The multifaceted role of CD4+ T cells in CD8+ T cell memory BJ Laidlaw, JE Craft, SM Kaech Nature Reviews Immunology 16 (2), 102-111, 2016 | 734 | 2016 |
Impaired HLA class I antigen processing and presentation as a mechanism of acquired resistance to immune checkpoint inhibitors in lung cancer S Gettinger, J Choi, K Hastings, A Truini, I Datar, R Sowell, A Wurtz, ... Cancer discovery 7 (12), 1420-1435, 2017 | 690 | 2017 |
Antigen-independent memory CD8 T cells do not develop during chronic viral infection EJ Wherry, DL Barber, SM Kaech, JN Blattman, R Ahmed Proceedings of the National Academy of Sciences 101 (45), 16004-16009, 2004 | 661 | 2004 |