Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 694 | 2020 |
Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae CM Ernst, JR Braxton, CA Rodriguez-Osorio, AP Zagieboylo, L Li, ... Nature medicine 26 (5), 705-711, 2020 | 218 | 2020 |
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2 CJ Bracken, SA Lim, P Solomon, NJ Rettko, DP Nguyen, BS Zha, ... Nature chemical biology 17 (1), 113-121, 2021 | 98 | 2021 |
Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis LC Kottyan, A Maddox, JR Braxton, EM Stucke, V Mukkada, PE Putnam, ... Genes & Immunity 20 (4), 281-292, 2019 | 37 | 2019 |
Structural insights of the p97/VCP AAA+ ATPase: How adapter interactions coordinate diverse cellular functionality JR Braxton, DR Southworth Journal of Biological Chemistry 299 (11), 2023 | 19 | 2023 |
The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions JR Braxton, CR Altobelli, MR Tucker, E Tse, AC Thwin, MR Arkin, ... Nature Structural & Molecular Biology 30 (12), 2009-2019, 2023 | 9 | 2023 |
Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly JR Braxton, H Shao, E Tse, JE Gestwicki, DR Southworth Nature Structural & Molecular Biology 31 (12), 1848-1858, 2024 | 3 | 2024 |
Author Correction: Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae CM Ernst, JR Braxton, CA Rodriguez-Osorio, AP Zagieboylo, L Li, ... Nature medicine 26 (8), 1307-1307, 2020 | 1 | 2020 |
Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading DR Kennedy, J Lemiere, C Tan, E Simental, J Braxton, RA Maxwell, ... bioRxiv, 2024 | | 2024 |
Multidomain interactions and ring opening of the p97 ATPase by the UBXD1 adapter JR Braxton, DR Southwort NATURE STRUCTURAL & MOLECULAR BIOLOGY 30 (12), 1842-1843, 2023 | | 2023 |
Research briefing JR Braxton, DR Southworth Nature Structural & Molecular Biology 30, 1842-1843, 2023 | | 2023 |
Visualizing dynamic states of human molecular chaperone complexes by high-resolution cryo-EM JR Braxton University of California, San Francisco, 2023 | | 2023 |
Cryo-EM structures reveal dramatic remodeling of the p97 hexamer by the multi-domain adapter UBXD1 J Braxton, C Altobelli, M Arkin, D Southworth Acta Cryst 78, a202, 2022 | | 2022 |
Structural basis for client engagement and chaperone cycling by human mitochondrial Hsp60 JR Braxton, JE Gestwicki, DR Southworth Biophysical Journal 121 (3), 323a, 2022 | | 2022 |