The metabolism of coumarins: In; Coumarins: Biology, Applications and mode of action. O Pelkonen, H Raunio, A Rautio, M Pasanen, M Lang Wiley, 1997 | 1451 | 1997 |
Metabolism of polycyclic aromatic hydrocarbons: etiologic role in carcinogenesis. O Pelkonen, DW Nebert Pharmacological reviews 34 (2), 189-222, 1982 | 749 | 1982 |
Inhibition and induction of human cytochrome P450 enzymes: current status O Pelkonen, M Turpeinen, J Hakkola, P Honkakoski, J Hukkanen, ... Archives of toxicology 82, 667-715, 2008 | 729 | 2008 |
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010 S Adler, D Basketter, S Creton, O Pelkonen, J Van Benthem, V Zuang, ... Archives of toxicology 85, 367-485, 2011 | 657 | 2011 |
Inhibition and induction of human cytochrome P450 (CYP) enzymes O Pelkonen, J Mäeenpäeä, P Taavitsainen, A Rautio, H Raunio Xenobiotica 28 (12), 1203-1253, 1998 | 531 | 1998 |
Age and cytochrome P450‐linked drug metabolism in humans: an analysis of 226 subjects with equal histopathologic conditions EA Sotaniemi, AJ Arranto, O Pelkonen, M Pasanen Clinical pharmacology & therapeutics 61 (3), 331-339, 1997 | 527 | 1997 |
Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human micro-somal protein and hepatocellularity … ZE Barter, MK Bayliss, PH Beaune, AR Boobis, DJ Carlile, RJ Edwards, ... Current drug metabolism 8 (1), 33-45, 2007 | 508 | 2007 |
Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung J Hukkanen, O Pelkonen, J Hakkola, H Raunio Critical reviews in toxicology 32 (5), 391-411, 2002 | 422 | 2002 |
Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility-a review H Raunio, K Husgafvel-Pursiainen, S Anttila, E Hietanen, A Hirvonen, ... Gene 159 (1), 113-121, 1995 | 413 | 1995 |
A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A gnes and identification of variant CYP2A6 alleles P Fernandez-Salguero, SMG Hoffman, S Cholerton, H Mohrenweiser, ... American Journal of Human Genetics 57 (3), 651, 1995 | 381 | 1995 |
Inhibition and induction of CYP enzymes in humans: an update J Hakkola, J Hukkanen, M Turpeinen, O Pelkonen Archives of Toxicology 94 (11), 3671-3722, 2020 | 331 | 2020 |
CYP2A6: a human coumarin 7-hydroxylase O Pelkonen, A Rautio, H Raunio, M Pasanen Toxicology 144 (1-3), 139-147, 2000 | 324 | 2000 |
Human placenta: a human organ for developmental toxicology research and biomonitoring P Myllynen, M Pasanen, O Pelkonen Placenta 26 (5), 361-371, 2005 | 301 | 2005 |
Xenobiotic-metabolizing cytochrome P450 enzymes in the human feto-placental unit: role in intrauterine toxicity J Hakkola, O Pelkonen, M Pasanen, H Raunio Critical reviews in toxicology 28 (1), 35-72, 1998 | 281 | 1998 |
Expression of xenobiotic-metabolizing cytochrome P450 forms in human full-term placenta J Hakkola, M Pasanen, J Hukkanen, O Pelkonen, J Mäenpää, ... Biochemical pharmacology 51 (4), 403-411, 1996 | 271 | 1996 |
Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells. J Hakkola, M Pasanen, O Pelkonen, J Hukkanen, S Evisalmi, S Anttila, ... Carcinogenesis 18 (2), 391-397, 1997 | 269 | 1997 |
Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population M Oscarson, RA McLellan, H Gullstén, QY Yue, MA Lang, ML Bernal, ... FEBS letters 448 (1), 105-110, 1999 | 267 | 1999 |
Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism M Oscarson, RA McLellan, H Gullstén, JAG Agúndez, J Benı́tez, A Rautio, ... FEBS letters 460 (2), 321-327, 1999 | 246 | 1999 |
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing D Basketter, H Clewell, I Kimber, A Rossi, B Blaauboer, R Burrier, ... | 245 | 2012 |
Expression of xenobiotic-metabolizing cytochrome P450 forms in human adult and fetal liver J Hakkola, M Pasanen, R Purkunen, S Saarikoski, O Pelkonen, ... Biochemical pharmacology 48 (1), 59-64, 1994 | 235 | 1994 |