| Osteoarthritis as a disease of the cartilage pericellular matrix F Guilak, RJ Nims, A Dicks, CL Wu, I Meulenbelt Matrix Biology 71, 40-50, 2018 | 441 | 2018 |
| Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis W Lee, RJ Nims, A Savadipour, Q Zhang, HA Leddy, F Liu, AL McNulty, ... Proceedings of the National Academy of Sciences 118 (13), e2001611118, 2021 | 176 | 2021 |
| Shearing of synovial fluid activates latent TGF-β MB Albro, AD Cigan, RJ Nims, KJ Yeroushalmi, SR Oungoulian, CT Hung, ... Osteoarthritis and cartilage 20 (11), 1374-1382, 2012 | 125 | 2012 |
| Heterogeneous engineered cartilage growth results from gradients of media-supplemented active TGF-β and is ameliorated by the alternative supplementation of latent TGF-β MB Albro, RJ Nims, KM Durney, AD Cigan, JJ Shim, G Vunjak-Novakovic, ... Biomaterials 77, 173-185, 2016 | 82 | 2016 |
| High seeding density of human chondrocytes in agarose produces tissue-engineered cartilage approaching native mechanical and biochemical properties AD Cigan, BL Roach, RJ Nims, AR Tan, MB Albro, AM Stoker, JL Cook, ... Journal of biomechanics 49 (9), 1909-1917, 2016 | 78 | 2016 |
| A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues RJ Nims, L Pferdehirt, NB Ho, A Savadipour, J Lorentz, S Sohi, J Kassab, ... Science Advances 7 (5), eabd9858, 2021 | 75 | 2021 |
| Accumulation of exogenous activated TGF-β in the superficial zone of articular cartilage MB Albro, RJ Nims, AD Cigan, KJ Yeroushalmi, T Alliston, CT Hung, ... Biophysical journal 104 (8), 1794-1804, 2013 | 75 | 2013 |
| Insulin, Ascorbate, and Glucose Have a Much Greater Influence Than Transferrin and Selenous Acid on the In Vitro Growth of Engineered Cartilage in … AD Cigan, RJ Nims, MB Albro, JD Esau, MP Dreyer, G Vunjak-Novakovic, ... Tissue Engineering Part A 19 (17-18), 1941-1948, 2013 | 57 | 2013 |
| Matrix production in large engineered cartilage constructs is enhanced by nutrient channels and excess media supply RJ Nims, AD Cigan, MB Albro, G Vunjak-Novakovic, CT Hung, ... Tissue Engineering Part C: Methods 21 (7), 747-757, 2015 | 51 | 2015 |
| Computational modeling of chemical reactions and interstitial growth and remodeling involving charged solutes and solid-bound molecules GA Ateshian, RJ Nims, S Maas, JA Weiss Biomechanics and modeling in mechanobiology 13, 1105-1120, 2014 | 50 | 2014 |
| Continuum theory of fibrous tissue damage mechanics using bond kinetics: application to cartilage tissue engineering RJ Nims, KM Durney, AD Cigan, A Dusséaux, CT Hung, GA Ateshian Interface Focus 6 (1), 20150063, 2016 | 46 | 2016 |
| Dynamic mechanical compression of devitalized articular cartilage does not activate latent TGF-β MB Albro, RJ Nims, AD Cigan, KJ Yeroushalmi, JJ Shim, CT Hung, ... Journal of biomechanics 46 (8), 1433-1439, 2013 | 45 | 2013 |
| Immunoengineering the next generation of arthritis therapies M Klimak, RJ Nims, L Pferdehirt, KH Collins, NS Harasymowicz, ... Acta biomaterialia 133, 74-86, 2021 | 41 | 2021 |
| Synthesis rates and binding kinetics of matrix products in engineered cartilage constructs using chondrocyte-seeded agarose gels RJ Nims, AD Cigan, MB Albro, CT Hung, GA Ateshian Journal of biomechanics 47 (9), 2165-2172, 2014 | 41 | 2014 |
| Regulation of chondrocyte biosynthetic activity by dynamic hydrostatic pressure: the role of TRP channels A Savadipour, RJ Nims, DB Katz, F Guilak Connective tissue research 63 (1), 69-81, 2022 | 36 | 2022 |
| Designer stem cells: Genome engineering and the next generation of cell‐based therapies F Guilak, L Pferdehirt, AK Ross, YR Choi, KH Collins, RJ Nims, DB Katz, ... Journal of Orthopaedic Research® 37 (6), 1287-1293, 2019 | 36 | 2019 |
| Nutrient channels and stirring enhanced the composition and stiffness of large cartilage constructs AD Cigan, RJ Nims, MB Albro, G Vunjak-Novakovic, CT Hung, ... Journal of biomechanics 47 (16), 3847-3854, 2014 | 35 | 2014 |
| Direct osmotic pressure measurements in articular cartilage demonstrate nonideal and concentration-dependent phenomena BK Zimmerman, RJ Nims, A Chen, CT Hung, GA Ateshian Journal of Biomechanical Engineering 143 (4), 041007, 2021 | 31 | 2021 |
| Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes A Savadipour, RJ Nims, N Rashidi, JM Garcia-Castorena, R Tang, ... Proceedings of the National Academy of Sciences 120 (30), e2221958120, 2023 | 30 | 2023 |
| Nutrient channels aid the growth of articular surface-sized engineered cartilage constructs AD Cigan, KM Durney, RJ Nims, G Vunjak-Novakovic, CT Hung, ... Tissue Engineering Part A 22 (17-18), 1063-1074, 2016 | 29 | 2016 |
