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Sofia Lövestam
Sofia Lövestam
PhD Student, MRC Laboratory of Molecular Biology
Подтвержден адрес электронной почты в домене mrc-lmb.cam.ac.uk
Название
Процитировано
Процитировано
Год
Cryo-EM structures of amyloid-β 42 filaments from human brains
Y Yang, D Arseni, W Zhang, M Huang, S Lövestam, M Schweighauser, ...
Science 375 (6577), 167-172, 2022
3632022
Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy
S Lövestam, FA Koh, B van Knippenberg, A Kotecha, AG Murzin, ...
Elife 11, e76494, 2022
2062022
Age-dependent formation of TMEM106B amyloid filaments in human brains
M Schweighauser, D Arseni, M Bacioglu, M Huang, S Lövestam, Y Shi, ...
Nature 605 (7909), 310-314, 2022
1392022
Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy
S Lövestam, M Schweighauser, T Matsubara, S Murayama, T Tomita, ...
FEBS open bio 11 (4), 999-1013, 2021
1272021
Disease-specific tau filaments assemble via polymorphic intermediates
S Lövestam, D Li, JL Wagstaff, A Kotecha, D Kimanius, SH McLaughlin, ...
Nature 625 (7993), 119-125, 2024
682024
Data-driven regularization lowers the size barrier of cryo-EM structure determination
D Kimanius, K Jamali, ME Wilkinson, S Lövestam, V Velazhahan, ...
Nature Methods 21 (7), 1216-1221, 2024
642024
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains
Y Yang, W Zhang, AG Murzin, M Schweighauser, M Huang, S Lövestam, ...
Acta neuropathologica 145 (3), 325-333, 2023
522023
High-throughput cryo-EM structure determination of amyloids
S Lövestam, SHW Scheres
Faraday Discussions 240, 243-260, 2022
452022
New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy
Y Yang, HJ Garringer, Y Shi, S Lövestam, S Peak-Chew, X Zhang, ...
Acta Neuropathologica 145 (5), 561-572, 2023
422023
Cryo‐EM structures of tau filaments from SH‐SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration
A Tarutani, S Lövestam, X Zhang, A Kotecha, AC Robinson, DMA Mann, ...
FEBS Open Bio 13 (8), 1394-1404, 2023
302023
Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
E Dimou, T Katsinelos, G Meisl, BJ Tuck, S Keeling, AE Smith, E Hidari, ...
Cell reports 42 (7), 2023
162023
Cleaved TMEM106B forms amyloid aggregates in central and peripheral nervous systems
M Bacioglu, M Schweighauser, D Gray, S Lövestam, T Katsinelos, ...
Acta Neuropathologica Communications 12 (1), 99, 2024
42024
Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W
C Qi, S Lövestam, AG Murzin, S Peak-Chew, C Franco, M Bogdani, ...
BioRxiv, 2024
42024
Tau filaments with the Alzheimer fold in cases withMAPTmutations V337M and R406W
C Qi, S Lövestam, AG Murzin, S Peak-Chew, C Franco, M Bogdani, ...
22024
Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments
S Lövestam, JL Wagstaff, T Katsinelos, SMV Freund, M Goedert, ...
bioRxiv, 2024.10. 23.619846, 2024
12024
Driving Tau Pathogenicity Seeding‐How Fibril Structure and Post‐Translational Modifications Alter Seeding Capacity
A Kasen, L Breton, L Meyerdirk, S Lövestam, J McPhail, A Louwrier, ...
Alzheimer's & Dementia 20, e094584, 2024
2024
Tau different conformers; seeds‐how do the first ones arise?
S Lövestam, Scheres and Goedert
Alzheimer's & Dementia 20, e085276, 2024
2024
Correction: Cleaved TMEM106B forms amyloid aggregates in central and peripheral nervous systems
M Bacioglu, D Gray, S Lövestam, T Katsinelos, A Quaegebeur, ...
Acta Neuropathologica Communications 12, 131, 2024
2024
Structural studies of the in vitro assembly of tau and α-synuclein amyloids
S Lövestam
2023
Age-Dependent Formation of TMEM106B Amyloid Filaments in Human Brain
GI Hallinan, SHW Scheres, T Revesz, M Huang, M Hasegawa, A Kotecha, ...
(No Title), 2021
2021
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Статьи 1–20