Lenalidomide promotes the development of TP53-mutated therapy-related myeloid neoplasms AS Sperling, VA Guerra, JA Kennedy, Y Yan, JI Hsu, F Wang, AT Nguyen, ... Blood, The Journal of the American Society of Hematology 140 (16), 1753-1763, 2022 | 98 | 2022 |
Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis A Tovy, JM Reyes, L Zhang, YH Huang, C Rosas, AC Daquinag, ... Elife 11, e72359, 2022 | 23 | 2022 |
Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome A Tovy, C Rosas, AS Gaikwad, G Medrano, L Zhang, JM Reyes, ... Haematologica 107 (4), 887, 2021 | 23 | 2021 |
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation CW Chen, L Zhang, R Dutta, A Niroula, PG Miller, CJ Gibson, AG Bick, ... Cell Stem Cell 30 (11), 1503-1519. e8, 2023 | 18 | 2023 |
PPM1D in Solid and Hematologic Malignancies: Friend and Foe? L Zhang, JI Hsu, MA Goodell Molecular Cancer Research 20 (9), 1365-1378, 2022 | 12 | 2022 |
Associations between cancer predisposition mutations and clonal hematopoiesis in patients with solid tumors S Franch-Expósito, M Mehine, RN Ptashkin, KL Bolton, C Bandlamudi, ... JCO Precision Oncology 7, e2300070, 2023 | 7 | 2023 |
Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation JM Reyes, A Tovy, L Zhang, AS Bortoletto, C Rosas, CW Chen, ... Iscience 27 (3), 2024 | 4 | 2024 |
SOD1 is a synthetic-lethal target in PPM1D-mutant leukemia cells L Zhang, JI Hsu, ED Braekeleer, CW Chen, TD Patel, AG Martell, ... Elife 12, RP91611, 2024 | | 2024 |
Protective Role of Oxaliplatin Among Platinum-Based Therapies in the Development of Therapy-Related Myeloid Neoplasms JS Connors, L Zhang, K Sasaki, CD DiNardo, NJ Short, N Daver, ... Blood 142, 4220, 2023 | | 2023 |
Clonal Competition: Cisplatin Treatment Drives Dominance of TP53-over Tet2-Mutant Stem Cell Clones K Wohlan, L Brunetti, JI Hsu, KA Matatall, RL Murdaugh, L Zhang, ... Blood 140 (Supplement 1), 8590-8591, 2022 | | 2022 |
Genome-Wide CRISPR Screen Reveals Dependency of PPM1D-mutant Cells on DNA Repair L Zhang, JI Hsu, ED Braekeleer, H Uryu, E Callen-Moreu, A Nussenzweig, ... Blood 140 (Supplement 1), 1994-1995, 2022 | | 2022 |