Chemical biology of protein arginine modifications in epigenetic regulation J Fuhrmann, KW Clancy, PR Thompson Chemical reviews 115 (11), 5413-5461, 2015 | 318 | 2015 |
McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR J Fuhrmann, A Schmidt, S Spiess, A Lehner, K Turgay, K Mechtler, ... Science 324 (5932), 1323-1327, 2009 | 202 | 2009 |
Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response A Schmidt, DB Trentini, S Spiess, J Fuhrmann, G Ammerer, K Mechtler, ... Molecular & cellular proteomics 13 (2), 537-550, 2014 | 128 | 2014 |
Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design DJ Slade, P Fang, CJ Dreyton, Y Zhang, J Fuhrmann, D Rempel, BD Bax, ... ACS chemical biology 10 (4), 1043-1053, 2015 | 127 | 2015 |
Modulation of ADAMTS13 secretion and specific activity by a combination of common amino acid polymorphisms and a missense mutation B Plaimauer, J Fuhrmann, G Mohr, W Wernhart, K Bruno, S Ferrari, ... Blood 107 (1), 118-125, 2006 | 126 | 2006 |
Protein arginine methylation and citrullination in epigenetic regulation J Fuhrmann, PR Thompson ACS chemical biology 11 (3), 654-668, 2016 | 115 | 2016 |
Ebselen, a small-molecule capsid inhibitor of HIV-1 replication S Thenin-Houssier, IMS De Vera, L Pedro-Rosa, A Brady, A Richard, ... Antimicrobial agents and chemotherapy 60 (4), 2195-2208, 2016 | 111 | 2016 |
S-nitrosylation of microtubule-associated protein 1B mediates nitric-oxide-induced axon retraction H Stroissnigg, A Trančíková, L Descovich, J Fuhrmann, W Kutschera, ... Nature cell biology 9 (9), 1035-1045, 2007 | 92 | 2007 |
Chemical and biological methods to detect post‐translational modifications of arginine DJ Slade, V Subramanian, J Fuhrmann, PR Thompson Biopolymers 101 (2), 133-143, 2014 | 82 | 2014 |
Identification of a binding site for unsaturated fatty acids in the orphan nuclear receptor Nurr1 IMS de Vera, PK Giri, P Munoz-Tello, R Brust, J Fuhrmann, ... ACS chemical biology 11 (7), 1795-1799, 2016 | 72 | 2016 |
Defining a conformational ensemble that directs activation of PPARγ IM Chrisman, MD Nemetchek, IMS De Vera, J Shang, Z Heidari, Y Long, ... Nature communications 9 (1), 1794, 2018 | 70 | 2018 |
A structural mechanism for directing corepressor-selective inverse agonism of PPARγ R Brust, J Shang, J Fuhrmann, SA Mosure, J Bass, A Cano, Z Heidari, ... Nature communications 9 (1), 4687, 2018 | 66 | 2018 |
Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria J Fuhrmann, B Mierzwa, DB Trentini, S Spiess, A Lehner, E Charpentier, ... Cell reports 3 (6), 1832-1839, 2013 | 56 | 2013 |
Chasing phosphoarginine proteins: development of a selective enrichment method using a phosphatase trap DB Trentini, J Fuhrmann, K Mechtler, T Clausen Molecular & Cellular Proteomics 13 (8), 1953-1964, 2014 | 55 | 2014 |
Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion M Wang, J Fuhrmann, PR Thompson Biochemistry 53 (50), 7884-7892, 2014 | 50 | 2014 |
Modification of the orthosteric PPARγ covalent antagonist scaffold yields an improved dual-site allosteric inhibitor R Brust, H Lin, J Fuhrmann, A Asteian, TM Kamenecka, DJ Kojetin ACS chemical biology 12 (4), 969-978, 2017 | 47 | 2017 |
Activity-based profiling reveals a regulatory link between oxidative stress and protein arginine phosphorylation J Fuhrmann, V Subramanian, DJ Kojetin, PR Thompson Cell chemical biology 23 (8), 967-977, 2016 | 47 | 2016 |
Synthesis and Use of a Phosphonate Amidine to Generate an Anti‐Phosphoarginine‐Specific Antibody J Fuhrmann, V Subramanian, PR Thompson Angewandte Chemie 127 (49), 14928-14931, 2015 | 47 | 2015 |
Cyanopyrrolidine inhibitors of ubiquitin specific protease 7 mediate desulfhydration of the active-site cysteine C Bashore, P Jaishankar, NJ Skelton, J Fuhrmann, BR Hearn, PS Liu, ... ACS Chemical Biology 15 (6), 1392-1400, 2020 | 29 | 2020 |
Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl … TS Hughes, J Shang, R Brust, IMS de Vera, J Fuhrmann, C Ruiz, ... Journal of medicinal chemistry 59 (22), 10335-10341, 2016 | 26 | 2016 |