α-Ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication: structure-based design, synthesis, and activity assessment L Zhang, D Lin, Y Kusov, Y Nian, Q Ma, J Wang, A Von Brunn, P Leyssen, ... Journal of medicinal chemistry 63 (9), 4562-4578, 2020 | 611 | 2020 |
Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking LE Sanderson, K Lanko, M Alsagob, R Almass, N Al-Ahmadi, M Najafi, ... Brain 144 (3), 769-780, 2021 | 46 | 2021 |
Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals K Lanko, K Eggermont, A Patel, S Kaptein, L Delang, CM Verfaillie, ... Antiviral Research 145, 82-86, 2017 | 46 | 2017 |
Molecular factors involved in spinal muscular atrophy pathways as possible disease-modifying candidates MA Maretina, GY Zheleznyakova, KM Lanko, AA Egorova, VS Baranov, ... Current Genomics 19 (5), 339-355, 2018 | 42 | 2018 |
Delineating the molecular and phenotypic spectrum of the SETD1B-related syndrome MJA Weerts, K Lanko, FJ Guzmán-Vega, A Jackson, R Ramakrishnan, ... Genetics in Medicine 23 (11), 2122-2137, 2021 | 32 | 2021 |
Viral engagement with host receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid L Sun, H Lee, HJ Thibaut, K Lanko, E Rivero-Buceta, C Bator, ... PLoS pathogens 15 (5), e1007760, 2019 | 29 | 2019 |
Discovery of multitarget agents active as broad-spectrum antivirals and correctors of cystic fibrosis transmembrane conductance regulator for associated pulmonary diseases S Tassini, L Sun, K Lanko, E Crespan, E Langron, F Falchi, M Kissova, ... Journal of Medicinal Chemistry 60 (4), 1400-1416, 2017 | 28 | 2017 |
Comprehensive multi-omics integration identifies differentially active enhancers during human brain development with clinical relevance S Yousefi, R Deng, K Lanko, EM Salsench, A Nikoncuk, HC van der Linde, ... Genome medicine 13, 1-27, 2021 | 19 | 2021 |
Multitarget CFTR modulators endowed with multiple beneficial side effects for cystic fibrosis patients: toward a simplified therapeutic approach S Tassini, E Langron, L Delang, C Mirabelli, K Lanko, E Crespan, ... Journal of Medicinal Chemistry 62 (23), 10833-10847, 2019 | 17 | 2019 |
Comparative analysis of the molecular mechanism of resistance to vapendavir across a panel of picornavirus species K Lanko, L Sun, M Froeyen, P Leyssen, L Delang, C Mirabelli, J Neyts Antiviral Research 195, 105177, 2021 | 16 | 2021 |
AMFR dysfunction causes autosomal recessive spastic paraplegia in human that is amenable to statin treatment in a preclinical model R Deng, E Medico-Salsench, A Nikoncuk, R Ramakrishnan, K Lanko, ... Acta Neuropathologica 146 (2), 353-368, 2023 | 14 | 2023 |
Assessing In Vitro Resistance Development in Enterovirus A71 in the Context of Combination Antiviral Treatment JN Kristina Lanko, Chenyan Shi, Shivaprasad Patil, Leen Delang, Jelle ... ACS Infect. Dis. 7 (10), 2801–2806, 2021 | 14 | 2021 |
The non-coding genome in genetic brain disorders: new targets for therapy? E Medico-Salsench, F Karkala, K Lanko, TS Barakat Essays in Biochemistry 65 (4), 671-683, 2021 | 9 | 2021 |
Antiviral effects of selected nucleoside analogues against human parechoviruses A1 and A3 K Lanko, Y Ma, L Delang, C Mirabelli, J Neyts Antiviral Research 162, 51-53, 2019 | 8 | 2019 |
Evaluation of mean percentage of full-length smn transcripts as a molecular biomarker of spinal muscular atrophy M Maretina, A Egorova, K Lanko, V Baranov, A Kiselev Genes 13 (10), 1911, 2022 | 5 | 2022 |
Expanding the mutational landscape and clinical phenotype of the YIF1B related brain disorder E Medico Salsench, R Maroofian, R Deng, K Lanko, A Nikoncuk, B Pérez, ... Brain 144 (10), e85-e85, 2021 | 2 | 2021 |
BRAIN-MAGNET: A novel functional genomics atlas coupled with convolutional neural networks facilitates clinical interpretation of disease relevant variants in non-coding … R Deng, E Perenthaler, A Nikoncuk, S Yousefi, K Lanko, R Schot, ... medRxiv, 2024.04. 13.24305761, 2024 | 1 | 2024 |
Hao-Fountain syndrome protein USP7 controls neuronal differentiation via BCOR–ncPRC1. 1 JW van der Meer, A Larue, JA van der Knaap, GE Chalkley, A Sijm, ... Genes & Development, 2025 | | 2025 |
Differential susceptibility of human motor neurons to infection with Usutu and West Nile virus EM Marshall, L Bauer, T Nelemans, S Sooksawasdi Na Ayudhya, ... Journal of Neuroinflammation 21 (1), 236, 2024 | | 2024 |
Hao-Fountain syndrome protein USP7 controls neuronal differentiation via BCOR-ncPRC1. 1 J Wolf van der Meer, A Larue, JA van der Knaap, GE Chalkley, A Sijm, ... bioRxiv, 2024.08. 04.606521, 2024 | | 2024 |