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Patrick C Kinnunen
Patrick C Kinnunen
Подтвержден адрес электронной почты в домене lbl.gov
Название
Процитировано
Процитировано
Год
Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space
EK Makowski, PC Kinnunen, J Huang, L Wu, MD Smith, T Wang, ...
Nature communications 13 (1), 3788, 2022
1162022
Computational methods for characterizing and learning from heterogeneous cell signaling data
PC Kinnunen, KE Luker, GD Luker, JJ Linderman
Current opinion in systems biology 26, 98-108, 2021
92021
Pre-existing cell states control heterogeneity of both EGFR and CXCR4 signaling
PC Spinosa, PC Kinnunen, BA Humphries, GD Luker, KE Luker, ...
Cellular and Molecular Bioengineering 14, 49-64, 2021
92021
Computational modeling implicates protein scaffolding in p38 regulation of Akt
PC Kinnunen, GD Luker, KE Luker, JJ Linderman
Journal of theoretical biology 555, 111294, 2022
52022
Machine learning-assisted imaging analysis of a human epiblast model
AM Resto Irizarry, SN Esfahani, Y Zheng, RZ Yan, P Kinnunen, J Fu
Integrative Biology 13 (9), 221-229, 2021
42021
Guide RNA structure design enables combinatorial CRISPRa programs for biosynthetic profiling
J Fontana, D Sparkman-Yager, I Faulkner, R Cardiff, C Kiattisewee, ...
Nature Communications 15 (1), 6341, 2024
32024
Oscillatory ERK signaling and morphology determine heterogeneity of breast cancer cell chemotaxis via MEK-ERK and p38-MAPK signaling pathways
KKY Ho, S Srivastava, PC Kinnunen, K Garikipati, GD Luker, KE Luker
Bioengineering 10 (2), 269, 2023
32023
Inference of weak-form partial differential equations describing migration and proliferation mechanisms in wound healing experiments on cancer cells
PC Kinnunen, S Srivastava, Z Wang, KKY Ho, BA Humphries, S Chen, ...
ArXiv, arXiv: 2302.09445 v2, 2024
2*2024
Integrating Inverse Reinforcement Learning into Data-Driven Mechanistic Computational Models: A Novel Paradigm to Decode Cancer Cell Heterogeneity
P Kinnunen, KKY Ho, S Srivastava, C Huang, W Shen, K Garikipati, ...
Frontiers in Systems Biology 4, 1333760, 2024
22024
DNA Origami and Rheology
P Kinnunen
The Ohio State University, 2016
22016
Characterizing heterogeneous single-cell dose responses computationally and experimentally using threshold inhibition surfaces and dose-titration assays
PC Kinnunen, BA Humphries, GD Luker, KE Luker, JJ Linderman
npj Systems Biology and Applications 10 (1), 42, 2024
12024
Machine learning-led semi-automated medium optimization reveals salt as key for flaviolin production in Pseudomonas putida
A Zournas, M Incha, T Radivojevic, V Blay, J Marti, Z Costello, M Schmidt, ...
2024
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Статьи 1–12